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Compounds Sorted by Binding Targets per Compound

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96   100   108   109   120   124   130   137   143   154   156   168   186   224   240   259   276   278   284   303   
304   310   315   323   339   369   370   371   372   373   374   375   376   377   378   380   381   383   384   
385   386   388   389   390   391   392   393   394   395   397   398   401   403   404   406   408   418   427   
429   443   447   515   
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
  • 72 kDa type IV collagenase
  • Carbonic Anhydrase IV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Collagenase (ChC)
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Interstitial collagenase
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Meprin A subunit beta
  • Neutrophil collagenase
  • Stromelysin-1
14 Ki 6 IC50
  • CHEMBL83508
  • Hydroxamate 9
  • N-hydroxy-2-[(4-methoxybenzene)sulfonamido]acetamide
  • BirA Bifunctional Protein
  • BirA Bifunctional Protein Mutant (V214A)
  • BirA Bifunctional Protein Mutant (V219A)
  • BirA Bifunctional Protein Mutant (W223A)
  • Streptavadin(N23A)
  • Streptavadin(N23E)
  • Streptavadin(S27A)
  • Streptavadin(W108F)
  • Streptavadin(W120F)
  • Streptavadin(W79F)
  • Streptavadin(Y43A)
  • Streptavidin
  • Streptavidin (Y43F)
  • Tyrosine-protein kinase ABL1
2 IC50 1 Kd
21 ΔG°
  • 5-[(3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazolidin-4-yl]pentanoic acid
  • Biotin
  • cid_171548
  • cid_253
  • Beta-chymotrypsin
  • Coagulation factor IX
  • Coagulation factor VII
  • Coagulation factor X
  • Complement factor H
  • Plasma kallikrein
  • Plasminogen
  • Prothrombin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin II
  • Trypsin-1
  • Urokinase-type plasminogen activator
  • Vitamin K-dependent protein C
35 Ki 4 IC50
  • 1-[3-(Aminomethyl)phenyl]-N-[3-fluoro-2-(methylsulfonyl)-[1,1-biphenyl]-4-yl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
  • 1-[3-(aminomethyl)phenyl]-N-[2-fluoro-4-(2-methanesulfonylphenyl)phenyl]-3-(trifluoromethyl)-1H-pyrazole-5-carboxamide
  • CHEMBL559015
  • DPC 423
  • DPC423
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Cytochrome P450 19A1
  • Steryl-sulfatase
12 Ki 23 IC50 1 Kd
  • 6-oxo-6,7,8,9,10,11-hexahydrocyclohepta[c]chromen-3-yl sulfamate
  • 667-COUMATE
  • 667COUMATE
  • BN83495
  • CHEMBL286738
  • CMT
  • STX64
  • {9-oxo-8-oxatricyclo[8.5.0.0^{2,7}]pentadeca-1(10),2(7),3,5-tetraen-5-yl} sulfamate
  • Androgen receptor
  • Bile salt export pump
  • Corticosteroid-binding globulin
  • Cytochrome P450 2J2
  • Cytochrome P450 3A
  • Glucocorticoid
  • Glucocorticoid receptor
  • Mineralocorticoid receptor
  • Organic anion-transporting polypeptide 1D1 (Oatp1d1)
  • P-glycoprotein (P-gp)
  • P-glycoprotein 1
  • P-glycoprotein 1 and 3 (MDR1a/MDR1b)
  • Rho GTPase-activating protein 35
  • Testis-specific androgen-binding protein
3 Ki 9 IC50 3 Kd 2 EC50
  • (1S,2R,10S,11S,14R,15S,17S)-14,17-dihydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadec-6-en-5-one
  • 11beta,17alpha,21-Trihydroxy-4-pregnene-3,20-dione
  • 3H-cortisol
  • HYDROCORTISONE
  • US10188667, Example 00023
  • [3H]cortisol
  • cortisol
  • Cereblon/Histone deacetylase 1
  • Cereblon/Histone deacetylase 2
  • Cereblon/Histone deacetylase 6
  • Histone deacetylase
  • Histone deacetylase 1
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Nicotinamide phosphoribosyltransferase
  • Nuclear receptor corepressor 1
3 Ki 42 IC50 1 EC50
  • 4-(acetylamino)-N-(2-amino-phenyl) benzamide
  • CI-994
  • N-(2-aminophenyl)-4-acetamidobenzamide
  • N-acetyldinaline
  • Aldehyde oxidase (AO)
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 3 (CA III)
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Cytochrome P450 19A1
  • Dipeptidyl peptidase IV
  • Estradiol receptor beta (ERβ)
  • Estrogen receptor
  • Transcriptional Regulator TtgR
  • Transcriptional Regulator TtgR Mutant R176G
  • Transcriptional Regulator TtgR-DNA
  • Urease subunit beta
7 Ki 6 IC50
6 ΔG°
  • α-CA inhibitor, 5
  • 5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
  • CHEMBL32571
  • Naringenin
  • Naringenin (NAR)
  • naringetol
  • salipurpol
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Collagenase 3
  • Matrix metalloproteinase 12
  • Matrix metalloproteinase 14
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • Metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Neutrophil collagenase
  • Stromelysin-1
21 IC50
  • US9206139, 1
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Collagenase 3
  • Interstitial collagenase
  • Matrix metalloproteinase 12
  • Matrix metalloproteinase 14
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Neutrophil collagenase
  • Stromelysin-1
20 IC50
  • US9206139, 4
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Collagenase 3
  • Interstitial collagenase
  • Matrix metalloproteinase 12
  • Matrix metalloproteinase 14
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Neutrophil collagenase
  • Stromelysin-1
20 IC50
  • US9206139, 5
  • Dual specificity protein phosphatase (VHR)
  • Dual specificity protein phosphatase CDC14A
  • Dual specificity protein phosphatase VHX (VHX)
  • Fas-associated protein-tyrosine phosphatase 1 (FAP1)
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Leukocyte common antigen
  • Low molecular weight phosphotyrosine protein phosphatase
  • Protein phosphatase 2A regulatory subunit B'
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase MEG2 (PTP-Meg2)
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Tyrosine-protein phosphatase non-receptor type 11
  • Tyrosine-protein phosphatase non-receptor type 2
16 Ki
  • US9217012, 10
  • CDKL2
  • Fibroblast growth factor receptor 2
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 14
  • PAK 1/CDC42
  • PITSLRE serine/threonine-protein kinase CDC2L1
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Serine/threonine-protein kinase B-raf
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
14 Kd
  • US9260417, 6
  • 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMG-CoA)
  • Bile Salt Export Pump, BSEP
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 1
  • HMG-CoA reductase
  • Organic anion-transporting polypeptide 1D1 (Oatp1d1)
  • Solute carrier family 22 member 11
  • Solute carrier family 22 member 6
  • Solute carrier family 22 member 7
  • Solute carrier family 22 member 8
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Solute carrier organic anion transporter family member 1B3 (OATP1B3)
  • Solute carrier organic anion transporter family member 2B1
  • Squalene monooxygenase
9 Ki 14 IC50 2 EC50
  • (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic acid
  • CHEMBL1144
  • Pravastatin
  • Cytoplasmic tyrosine-protein kinase BMX
  • Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7)
  • Epidermal growth factor receptor
  • Non-receptor tyrosine-protein kinase TYK2
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
14 Ki 55 IC50
  • PF-06651600
  • US9617258, Example 5
  • Apoptosis regulator Bcl-2
  • Apoptosis regulator Bcl-2/Bcl-2 homologous antagonist/killer
  • Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH).
  • Apoptosis regulator Bcl-XL
  • BCL-W
  • Bcl-2 homologous antagonist/killer
  • Bcl-2-like protein 1
  • Bcl-2-related protein A1
  • Bcl-xL/Bcl-2-binding component 3
  • Bcl2-antagonist of cell death (BAD)
  • Casein Kinase II
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • Induced myeloid leukemia cell differentiation protein Mcl-1 homolog
  • Isoform Bcl-X(L)
30 Ki 27 IC50 5 Kd 3 EC50
  • 4-(4-{[2-(4-chlorophenyl)phenyl]methyl}piperazin-1-yl)-N-[(4-{[(2R)-4-(dimethylamino)-1-(phenylsulfanyl)butan-2-yl]amino}-3-nitrobenzene)sulfonyl]benzamide
  • ABT-737
  • CHEMBL376408
  • N-Benylpiperazine derivative, 2
  • US9125913, ABT-737
  • 15-Lipoxygenase (LoxA)
  • 5-hydroxytryptamine receptor 1A
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • D(2) dopamine receptor
  • Histamine H1 receptor
  • Histamine H4 receptor
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • P-glycoprotein 1
  • Potassium voltage-gated channel subfamily H member 2
  • Replicase polyprotein 1ab
1 Ki 14 IC50
  • 1-(4-tert-butylphenyl)-4-[4-(diphenylmethoxy)piperidin-1-yl]butan-1-one
  • Bactil
  • CHEMBL305660
  • Ebastine
  • Kestine
  • NCGC00164603
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Arachidonate 5-lipoxygenase
  • Cytochrome P450 1A
  • Cytochrome P450 1A1
  • Cytochrome P450 1B1
  • Epidermal growth factor receptor
  • Inositol hexakisphosphate kinase 2
  • Inositol polyphosphate multikinase
  • Mitogen-activated protein kinase 10
  • Mitogen-activated protein kinase 14
  • Sialidase 2
  • Xanthine dehydrogenase
  • alpha-Amylase
5 Ki 19 IC50 1 Other
  • 5,7-dihydroxy-2-(4-methoxyphenyl)-4H-chromen-4-one
  • Acacetin
  • CHEMBL243664
  • B-RAF V600E
  • C-RAF (Y340D Y341D)
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Fibroblast growth factor receptor 2
  • Insulin-like growth factor I receptor
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase B-raf
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
14 IC50
  • US9388165, 1
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Carbon monoxide dehydrogenase (CODH)
  • Dual specificity mitogen-activated protein kinase kinase 1
  • Dual specificity phosphatase Cdc25B
  • Dual specificity protein phosphatase 1
  • Histone-lysine N-methyltransferase EHMT1
  • Human rhinovirus A protease
  • Indoleamine 2,3-dioxygenase
  • MKP-3
  • Monoamine oxidase B (MAO-B)
  • Papain
  • Protein G9a (G9a)
  • RAC-alpha serine/threonine-protein kinase
2 Ki 15 IC50 1 Kd
  • 1,4-Naphthoquinone
  • 1,4-Naphthoquinone (5a)
  • 1,4-dihydronaphthalene-1,4-dione
  • 1,4-naphtho-quinone, 3
  • CHEMBL55934
  • Aurora kinase B
  • Axin-1/Glycogen synthase kinase-3 beta
  • Bromodomain-containing protein 4
  • Casein kinase I isoform alpha
  • MAP-Microtubule Affinity-Regulating Kinase 3 (MARK3)
  • Ribosomal S6 Kinase 1 (RSK-1)
  • Ribosomal protein S6 kinase alpha 2
  • Ribosomal protein S6 kinase alpha 6
  • Ribosomal protein S6 kinase alpha-3
  • Serine/threonine-protein kinase MST2
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase VRK1
  • Tyrosine-protein kinase JAK2
  • p90RSK
20 IC50 3 Kd
  • 2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimethyl-8-(3-methylbutyl)-5,6,7,8-tetrahydropteridin-6-one
  • BI-D1870
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Nuclear receptor ROR-alpha
  • Nuclear receptor ROR-beta
  • Nuclear receptor ROR-gamma
  • Nuclear receptor ROR-gamma (RORC)
  • Nuclear receptor subfamily 1 group I member 2
  • Oxysterols receptor LXR-alpha
  • Oxysterols receptor LXR-beta
8 IC50 6 EC50
  • US9458171, 387
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Nuclear receptor ROR-alpha
  • Nuclear receptor ROR-beta
  • Nuclear receptor ROR-gamma
  • Nuclear receptor ROR-gamma (RORC)
  • Nuclear receptor subfamily 1 group I member 2
  • Oxysterols receptor LXR-alpha
  • Oxysterols receptor LXR-beta
8 IC50 6 EC50
  • US9458171, 392
  • ADRB2
  • Adrenergic receptor beta
  • Bcl-2-like protein 11
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Beta-3 adrenergic receptor
  • Bile salt export pump
  • Calcium channel (Type L)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Multidrug resistance-associated protein 4
  • Serotonin 1B/1D receptor
  • Serum albumin
  • Voltage-gated L-type calcium channel
6 Ki 15 IC50 5 Kd 1 EC50
  • CHEMBL471
  • N-{4-[1-hydroxy-2-(propan-2-ylamino)ethyl]phenyl}methanesulfonamide
  • SOTALOL HYDROCHLORIDE
  • Sotalol
  • Sotalol,(+)
  • Sotalol,(-)
  • cid_66245
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
14 Ki
  • 2-(hydrazinecarbonyl)-3-(2,3,4,5,6-pentafluorophenyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2n
  • indole sulfonamide, 8n
  • 72 kDa type IV collagenase
  • ADAM17
  • Collagenase 3
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Disintegrin and metalloproteinase domain-containing protein 33
  • Interstitial collagenase
  • Matrix metalloproteinase 15
  • Matrix metalloproteinase 16
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Stromelysin-1
  • TNF-alpha-Converting Enzyme
28 Ki 10 IC50
  • (2R)-N-hydroxy-2-[(3S)-3-methyl-3-{4-[(2-methylquinolin-4-yl)methoxy]phenyl}-2-oxopyrrolidin-1-yl]propanamide
  • BMCL181958 Compound 1
  • CHEMBL148169
  • IK682
  • α-Carbonic anhydrase (αCA)
  • β-Carbonic anhydrase (βCA)
  • Alpha carbonic anhydrase
  • Alpha-carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Gamma-carbonic anhydrase
48 Ki
  • CHEMBL180485
  • CO3(2-)
  • SODIUM CARBONATE
  • carbonate
  • carbonate ion
  • Coagulation factor III/Factor VIIa (fVIIa)
  • NAD-Dependent Deacetylase Sirtuin-1
  • NAD-dependent deacetylase HST2
  • NAD-dependent deacetylase sirtuin 1
  • NAD-dependent deacetylase sirtuin 2
  • NAD-dependent deacetylase sirtuin 3
  • NAD-dependent histone deacetylase SIR2
  • NAD-dependent protein deacetylase
  • NAD-dependent protein deacetylase sirtuin-3 (SIRT3)
  • NAD-dependent protein deacetylase sirtuin-5 (SIRT5)
  • Poly [ADP-ribose] polymerase 1
  • Putative silent information regulator 2
  • Sirtuin-6 (SIRT6)
  • poly-ADP-ribose polymerase 2 (PARP2)
1 Ki 52 IC50
  • 3-Pyridinecarboxamide
  • CHEMBL1140
  • NAM
  • niacinamide
  • nicotinamide
  • pyridine-3-carboxamide
  • Human diphtheria toxin-like ADP-ribosyltransferase (ARTD3 or PARP3)
  • Mono [ADP-ribose] polymerase PARP16
  • Poly [ADP-ribose] polymerase 1
  • Poly [ADP-ribose] polymerase 10
  • Poly [ADP-ribose] polymerase 12
  • Poly [ADP-ribose] polymerase 15
  • Poly [ADP-ribose] polymerase 2
  • Poly [ADP-ribose] polymerase 4
  • Poly [ADP-ribose] polymerase 6
  • Poly [ADP-ribose] polymerase tankyrase-1
  • Poly [ADP-ribose] polymerase tankyrase-2
  • Protein mono-ADP-ribosyltransferase PARP3
  • Tankyrase 1/2
  • poly-ADP-ribose polymerase 2 (PARP2)
88 IC50 2 Kd 4 EC50
  • 4-({3-[(4-cyclopropanecarbonylpiperazin-1-yl)carbonyl]-4-fluorophenyl}methyl)-1,2-dihydrophthalazin-1-one
  • Acylpiperazine analogue, 47
  • Olaparib
  • US10174023, AZD2281
  • US10597399, Compound AZD2281
  • US9187430, AZD-2281
  • US9255106, AZD2281
  • 5-HT5B
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • HTR2B
  • HTR5A
  • HTR6
  • Monoamine oxidase
  • Serotonin (5-HT) receptor
  • Serotonin 1 (5-HT1) receptor
  • Serotonin 2 (5-HT2) receptor
  • Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
64 Ki 4 IC50 4 EC50
  • 1-(4-iodo-2,5-dimethoxyphenyl)propan-2-amine
  • CHEMBL6616
  • DOI
  • DOI,(+)
  • DOI,(-)
  • [125I]2,5-dimethoxy-4-iodoamphetamine
  • [125I]4-iodo-2,5-dimethoxyphenylisopropylamine
  • [125I]DOI
  • BRD9 (aa 134-239)
  • Bromodomain adjacent to zinc finger domain protein 2A
  • Bromodomain adjacent to zinc finger domain protein 2B
  • Bromodomain-containing protein 4
  • Bromodomain-containing protein 9
  • CREB-binding protein
  • Cat eye syndrome critical region protein 2
  • HIF1A/p300/CREB-binding protein
  • Peregrin
  • Probable global transcription activator SNF2L2
  • Protein polybromo-1
  • Transcription activator BRG1
  • Transcription initiation factor TFIID subunit 1
  • Transcription intermediary factor 1-alpha
38 IC50
  • N,N-dimethyl-3-(6-methyl-7-oxo-1H-pyrrolo[2,3-c]pyridin-4-yl)benzamide
  • US10150767, Example 22
  • Dual specificity protein phosphatase (VHR)
  • Eukaryotic translation initiation factor 4H
  • Focal adhesion kinase 1
  • Heat Shock 70kDa Protein 1
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Integrin alpha-4
  • N-formyl peptide receptor 2
  • PTK2B protein tyrosine kinase 2 beta (PTK2B)
  • STAT3
  • Transcription Factor STAT1
  • fMet-Leu-Phe receptor
  • heat shock 70kDa protein 8 isoform 1
  • insulin-degrading enzyme isoform 1 precursor
  • poly(A) binding protein, cytoplasmic 1
2 Ki 15 IC50 2 EC50
  • (4-methoxy-1,3-benzothiazol-2-yl)-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]amine
  • 4-methoxy-N-[5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-yl]-1,3-benzothiazol-2-amine
  • MLS000045458
  • N-(4-methoxy-1,3-benzothiazol-2-yl)-5-(4-methoxyphenyl)-1,3,4-oxadiazol-2-amine
  • SMR000027218
  • cid_3236395
  • Apoptotic peptidase activating factor 1
  • Caspase-3
  • Caspase-9
  • Dual Specificity Protein Phosphatase 1
  • Heat shock protein HSP 90-alpha
  • MKP-3
  • PPP5C protein
  • SUMO-1-specific protease
  • SUMO/sentrin specific peptidase family member 8
  • SUMO1 activating enzyme subunit 1
  • Voltage-dependent T-type calcium channel subunit alpha-1H
  • protein phosphatase 1, catalytic subunit, alpha isoform 3
  • tyrosyl-DNA phosphodiesterase 2
  • ubiquitin-conjugating enzyme E2I
15 IC50 1 EC50
  • 2-chloranyl-N-(3-cyano-1-prop-2-enyl-pyrrolo[3,2-b]quinoxalin-2-yl)benzamide
  • 2-chloro-N-(3-cyano-1-prop-2-enyl-2-pyrrolo[3,2-b]quinoxalinyl)benzamide
  • 2-chloro-N-(3-cyano-1-prop-2-enylpyrrolo[3,2-b]quinoxalin-2-yl)benzamide
  • MLS000079922
  • N-(1-allyl-3-cyano-pyrrolo[3,2-b]quinoxalin-2-yl)-2-chloro-benzamide
  • SMR000039798
  • cid_658849
  • Apoptotic peptidase activating factor 1
  • Caspase-9
  • Cathepsin B
  • Cathepsin S
  • DNA recombination protein RecA
  • Dual Specificity Protein Phosphatase 1
  • Dual specificity phosphatase Cdc25B
  • Heat shock protein HSP 90-alpha
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • MKP-3
  • Phospholipase A2
  • Procathepsin L
  • cysteine protease ATG4B isoform a
33 IC50 2 EC50
  • 1,8-bis(azanyl)-3,6-dipyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile
  • 1,8-diamino-3,6-bis(1-pyrrolidinyl)-2,7-naphthyridine-4-carbonitrile
  • 1,8-diamino-3,6-dipyrrolidin-1-yl-2,7-naphthyridine-4-carbonitrile
  • 1,8-diamino-3,6-dipyrrolidino-2,7-naphthyridine-4-carbonitrile
  • MLS000054131
  • SMR000061605
  • cid_2997948
  • 26S Proteasome regulatory subunit Rpn11 (Rpn11)
  • 72 kDa type IV collagenase
  • Acetylcholinesterase
  • Bile salt export pump
  • Botulinum neurotoxin type A
  • Cholinesterases
  • Fructose-1,6-bisphosphate aldolase (FBA)
  • Heat shock protein HSP 90-alpha
  • Indoleamine 2,3-dioxygenase
  • LDL-associated phospholipase A2
  • Lanosterol synthase
  • Methionine Aminopeptidase Type 1 (MetAP1)
  • Methionine aminopeptidase 2
  • Thermolysin
1 Ki 22 IC50
  • 8-quinolinol
  • CHEMBL310555
  • US10005735, Table 1.7
  • US9394254, 6
  • cid_1923
  • oxine
  • quinolin-8-ol
  • Bcl-2-related protein A1
  • G protein signalling regulator 19
  • Glucose 6-phosphate dehydrogenase (G6PD)
  • MPI protein
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • RGS7
  • Regulator of G-protein signaling 8
  • Trypanosoma brucei RNA editing ligase 1
  • glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
  • glutathione S-transferase
  • lens epithelium-derived growth factor p75
  • leucine aminopeptidase
  • regulator of G-protein signaling 4
  • regulator of G-protein signalling 16
5 Ki 9 IC50 13 EC50
  • (4E)-4-[[(2-ethylimino-4-methyl-1,3-thiazol-3-yl)amino]methylidene]-2,3-bis(oxidanyl)cyclohexa-2,5-dien-1-one
  • (4E)-4-[[(2-ethylimino-4-methyl-1,3-thiazol-3-yl)amino]methylidene]-2,3-dihydroxycyclohexa-2,5-dien-1-one
  • (4E)-4-[[(2-ethylimino-4-methyl-3-thiazolyl)amino]methylidene]-2,3-dihydroxy-1-cyclohexa-2,5-dienone
  • (4E)-4-[[(2-ethylimino-4-methyl-4-thiazolin-3-yl)amino]methylene]-2,3-dihydroxy-cyclohexa-2,5-dien-1-one
  • (4Z)-4-[[(2-ethylimino-4-methyl-4-thiazolin-3-yl)amino]methylene]-2,3-dihydroxy-cyclohexa-2,5-dien-1-one
  • MLS000564170
  • SMR000151702
  • cid_5825518
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 3A
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • HTR4
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
19 Ki 10 IC50
  • 2-ethyl-5-methoxy-N,N-dimethyltryptamine
  • CHEMBL267615
  • EDMT
  • EMDT
  • [2-(2-ethyl-5-methoxy-1H-indol-3-yl)ethyl]dimethylamine, 6
  • Apoptotic peptidase activating factor 1
  • Beta lactamase
  • Caspase-3
  • Caspase-9
  • Hepatocyte nuclear factor 4-alpha
  • MPI protein
  • SUMO-1-specific protease
  • SUMO/sentrin specific peptidase family member 8
  • Serine/threonine-protein kinase RIPK2
  • perilipin-1
  • perilipin-5
  • protein artemis isoform a
  • putative hexokinase HKDC1
  • streptokinase A precursor
15 IC50 1 EC50
  • 2-Methyl-3-(4-methyl-benzoyl)-naphtho[1,2-b]furan-4,5-dione
  • 2-methyl-3-(4-methylbenzoyl)benzo[g][1]benzofuran-4,5-dione
  • 2-methyl-3-(4-methylphenyl)carbonyl-benzo[g][1]benzofuran-4,5-dione
  • 2-methyl-3-[(4-methylphenyl)-oxomethyl]benzo[g]benzofuran-4,5-dione
  • 2-methyl-3-p-toluoyl-benzo[g]benzofuran-4,5-quinone
  • MLS000554106
  • SMR000146423
  • cid_3696529
  • Bile salt export pump
  • Eukaryotic translation initiation factor 4E (eIF4E)
  • FK506-binding protein 1B
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Nuclear receptor subfamily 1 group I member 2
  • Peptidyl-prolyl cis-trans isomerase FKBP1A
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Peptidyl-prolyl cis-trans isomerase FKBP5
  • Programmed cell death protein 4
  • Sarcoplasmic/endoplasmic reticulum calcium ATP-ase
  • Serine/threonine-protein kinase mTOR (mTOR)
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • mTOR/FKBP12A/FKBP12B
  • mTORC2
3 Ki 13 IC50 3 Kd 4 EC50
  • Rapamycin C-7, analog 4
  • SIROLIMUS
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
14 IC50
  • US10294227, Code 103
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
14 IC50
  • US10294227, Code 105
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
14 IC50
  • US10294227, Code 402
  • Apoptotic peptidase activating factor 1
  • Beta-galactosidase
  • C-C chemokine receptor type 6 (CCR6)
  • Caspase-3
  • Caspase-9
  • DNA damage-inducible transcript 3 protein
  • Glucose 6-phosphate dehydrogenase (G6PD)
  • SUMO-1-specific protease
  • SUMO/sentrin specific peptidase family member 8
  • Serine/threonine-protein kinase PLK1
  • XBP1
  • glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
  • neutrophil cytosolic factor 1
  • putative hexokinase HKDC1
19 IC50 2 EC50
  • 2-[[(4E)-1-keto-4-(2-thienylsulfonylimino)-2-naphthyl]amino]benzoic acid methyl ester
  • 2-[[(4E)-1-oxo-4-thiophen-2-ylsulfonylimino-2-naphthalenyl]amino]benzoic acid methyl ester
  • MLS000521465
  • SMR000131873
  • cid_9550941
  • methyl 2-[[(4E)-1-oxidanylidene-4-thiophen-2-ylsulfonylimino-naphthalen-2-yl]amino]benzoate
  • methyl 2-[[(4E)-1-oxo-4-thiophen-2-ylsulfonyliminonaphthalen-2-yl]amino]benzoate
  • Beta-galactosidase
  • C-C chemokine receptor type 6 (CCR6)
  • DNA damage-inducible transcript 3 protein
  • E3 ubiquitin-protein ligase Mdm2
  • G protein signalling regulator 19
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • RGS7
  • Regulator of G-protein signaling 8
  • XBP1
  • eukaryotic translation initiation factor 4 gamma, 1 isoform 4
  • matrix metalloproteinase 1
  • putative hexokinase HKDC1
  • regulator of G-protein signaling 4
  • regulator of G-protein signalling 16
5 Ki 9 IC50 13 EC50
  • 2,5-bis(chloranyl)-3-piperidin-1-yl-6-(2-piperidin-1-yl-1,3-thiazol-5-yl)cyclohexa-2,5-diene-1,4-dione
  • 2,5-dichloro-3-(1-piperidinyl)-6-[2-(1-piperidinyl)-1,3-thiazol-5-yl]benzo-1,4-quinone
  • 2,5-dichloro-3-(1-piperidinyl)-6-[2-(1-piperidinyl)-5-thiazolyl]cyclohexa-2,5-diene-1,4-dione
  • 2,5-dichloro-3-piperidin-1-yl-6-(2-piperidin-1-yl-1,3-thiazol-5-yl)cyclohexa-2,5-diene-1,4-dione
  • 2,5-dichloro-3-piperidino-6-(2-piperidinothiazol-5-yl)-p-benzoquinone
  • MLS000550549
  • SMR000115104
  • cid_406171
  • 26S Proteasome regulatory subunit Rpn11 (Rpn11)
  • Alkaline phosphatase placental-like
  • Alkaline phosphatase, tissue-nonspecific isozyme
  • Alpi
  • Dual specificity protein phosphatase (VHR)
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Intestinal alkaline phosphatase
  • POsterior Segregation family member (pos-1)
  • Phospholipase A2
  • RecName: Full=Zinc finger protein mex-5
  • Thrombin
  • cysteine protease ATG4B isoform a
  • likely tRNA 2'-phosphotransferase
  • unnamed protein product
12 IC50 6 EC50
  • 4-chloranyl-N-(3,4-dihydro-2H-thiochromen-4-yl)-3-sulfamoyl-benzamide
  • 4-chloro-3-sulfamoyl-N-thiochroman-4-yl-benzamide
  • 4-chloro-N-(3,4-dihydro-2H-1-benzothiopyran-4-yl)-3-sulfamoylbenzamide
  • 4-chloro-N-(3,4-dihydro-2H-thiochromen-4-yl)-3-sulfamoylbenzamide
  • MLS-0336143.0001
  • cid_16330874
  • Dual specificity protein phosphatase (VHR)
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • MKP-3
  • Phospholipase C, gamma 1
  • Phospholipase C-beta-3
  • Voltage-gated calcium channel subunit alpha Cav2.2
  • cardiac alpha tropomyosin
  • eukaryotic translation initiation factor 4 gamma, 1 isoform 4
  • glutathione S-transferase
  • hypothetical protein SA1422
  • lens epithelium-derived growth factor p75
  • neuronal munc18-1 binding protein
19 IC50 1 EC50
  • 3-(2-{(E)-[1-(4-chlorophenyl)-2,5-dioxoimidazolidin-4-ylidene]methyl}-1H-pyrrol-1-yl)benzoic acid
  • 3-[2-[(E)-[1-(4-chlorophenyl)-2,5-bis(oxidanylidene)imidazolidin-4-ylidene]methyl]pyrrol-1-yl]benzoic acid
  • 3-[2-[(E)-[1-(4-chlorophenyl)-2,5-diketo-imidazolidin-4-ylidene]methyl]pyrrol-1-yl]benzoic acid
  • 3-[2-[(E)-[1-(4-chlorophenyl)-2,5-dioxo-4-imidazolidinylidene]methyl]-1-pyrrolyl]benzoic acid
  • 3-[2-[(E)-[1-(4-chlorophenyl)-2,5-dioxoimidazolidin-4-ylidene]methyl]pyrrol-1-yl]benzoic acid
  • MLS000686463
  • SMR000313306
  • cid_6104167
  • NAD-Dependent Deacetylase Sirtuin-1
  • NAD-dependent deacetylase sirtuin 2
  • P2X purinoceptor 1
  • P2X purinoceptor 2
  • P2X purinoceptor 3
  • P2X purinoceptor 4
  • P2X purinoceptor 7
  • Protein-arginine N-methyltransferase 1
  • Purinergic, P2X2
  • Replicase polyprotein 1ab
  • Transcription Factor STAT1
  • Transcription Factor STAT3
  • Transcription factor STAT5a (STAT5a)
  • Transcription factor STAT5b (STAT5b)
10 Ki 10 IC50
  • 4-Methyl-8-{4-methyl-3-[3-(3-{3-[2-methyl-5-(4,6,8-trisulfo-naphthalen-1-ylcarbamoyl)-phenylcarbamoyl]-phenyl}-ureido)-benzoylamino]-benzoylamino}-naphthalene-1,3,5-trisulfonic acid; hexa-kis Sodium salt
  • 5,5',5''-[1,3,6-naphthalenetriyltris(sulfonylimino)]tris[1,3-benzenesulfonate analogue
  • CHEMBL265502
  • SURAMIN HEXASODIUM
  • Suramin sodium
  • suramin
  • suramin Na
  • Alpha-chymotrypsin
  • Beta-lactamase AmpC
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Complement C5
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • EBifunctional epoxide hydrolase 2
  • Epoxide hydratase
  • Epoxide hydrolase 2
  • Malate dehydrogenase cytoplasmic
  • Multidrug resistance-associated protein 4
  • Prostaglandin E synthase/G/H synthase 2
2 Ki 23 IC50 1 Kd
  • 3-(4,5-Diphenyl-oxazol-2-yl)-propionic acid
  • CHEMBL1071
  • Daypro
  • OXAPROZIN
  • WY-21743
  • oxaprosin
  • Aurora kinase A/B
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Aurora-C/INCENP
  • Discoidin domain-containing receptor 2
  • High affinity nerve growth factor receptor
  • Mitogen-activated protein kinase 10/Receptor-interacting serine/threonine-protein kinase 1
  • Protein delta homolog 1
  • Receptor-interacting protein 1 (RIPK1)
  • Receptor-interacting serine/threonine-protein kinase 1
  • Serine/threonine-protein kinase Aurora-C
  • Serine/threonine-protein kinase PLK4
  • Serine/threonine-protein kinase TBK1
  • Tyrosine-protein kinase receptor FLT3
15 Ki 32 IC50 9 Kd
  • MK-045
  • MK-0457
  • TOZASERTIB
  • US9249124, VX680
  • VX-68
  • VX-680
  • Acetylcholinesterase
  • Cholinergic, muscarinic
  • MCOLN3 protein
  • Muscarinic acetylcholine receptor
  • Muscarinic acetylcholine receptor DM1
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M2 and M4
  • Muscarinic acetylcholine receptor M2 and M5
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Serotonin (5-HT) receptor
  • transient receptor potential cation channel, subfamily N, member 1
50 Ki 25 IC50 2 Kd 12 EC50
  • (oxotremorine)1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one
  • 1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one
  • 1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one (oxotremorphine)
  • 1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one(Oxotremorine)
  • 1-[4-(2-oxo-pyrrolidin-1-yl)-but-2-ynyl]-pyrrolidinium
  • CHEMBL7634
  • Oxotremorine
  • Oxotremorine1-(4-Pyrrolidin-1-yl-but-2-ynyl)-pyrrolidin-2-one
  • cid_4630
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Adenylate cyclase
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • DRD1
  • DRD2
  • Dopamine D1 receptor
  • Dopamine D1B
  • Dopamine receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
46 Ki 5 IC50 2 Kd 12 EC50
  • (R)-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
  • (R)-7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium
  • 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
  • 1-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol(SKF38393)
  • 7,8-Dihydroxy-1-phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepinium(R(+)SKF38393)
  • CHEMBL1467585
  • CHEMBL24077
  • R(+)SKF 383931-Phenyl-2,3,4,5-tetrahydro-1H-benzo[d]azepine-7,8-diol
  • SK&F-383933
  • SK-38393
  • SK-383933
  • SKF 38393
  • SKF 38393 (+)
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Norepinephrine Monoamine transporters
  • Norepinephrine transporter
  • Serotonin 2 (5-HT2) receptor
  • Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
19 Ki 10 IC50 1 Kd 2 EC50
  • (+/-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine
  • (-)2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine
  • (R)-(-)-2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine
  • (S)-(+)-2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine
  • 2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine
  • 2-Benzo[1,3]dioxol-5-yl-1-methyl-ethylamine((R)-(-)-MDA)
  • 3,4-methylenedioxyamphetamine
  • CHEMBL6731
  • MDA
  • MDA, (R,S)
  • MDA,R(-)
  • Tenamfetamine
  • methylenedioxyamphetamine
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Insulin-like growth factor I receptor
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase ABL1
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
14 IC50
  • CHEMBL3233767
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Insulin-like growth factor I receptor
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase ABL1
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
14 IC50
  • CHEMBL3233785
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Imidazoline I2-receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Nociceptin/Orphanin FQ, NOP receptor
  • Nuclear receptor subfamily 1 group I member 2
  • OPRD1
  • Opioid receptor
  • Opioid receptors; mu & delta
  • Opioid receptors; mu and delta
  • P-glycoprotein 1
  • Potassium voltage-gated channel subfamily H member 2
  • Solute carrier family 22 member 1
40 Ki 33 IC50 7 EC50
  • 4-(4-Chloro-benzyl)-2-(1-methyl-azepan-4-yl)-2H-phthalazin-1-one
  • CHEMBL596
  • Duragesic-100
  • Duragesic-12
  • Duragesic-25
  • Duragesic-50
  • Duragesic-75
  • FENTANYL
  • FENTANYL CITRATE
  • FENTANYL-HCl
  • Fentanyl-100
  • Fentanyl-12
  • Fentanyl-25
  • Fentanyl-50
  • Fentanyl-75
  • Fentora
  • Innovar
  • Ionsys
  • N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide
  • N-(1-Phenethyl-piperidin-4-yl)-N-phenyl-propionamide(Fentanyl)
  • N-(1-phenethylpiperidin-4-yl)-N-phenylpropionamide
  • 5-hydroxytryptamine receptor 2A
  • ADENOSINE A2
  • Adenosine A1 receptor
  • Adenosine A2 receptor
  • Adenosine A2a receptor
  • Adenosine Receptors A2a (A2a)
  • Adenosine deaminase
  • Adenosine receptor
  • Adenosine receptor A1
  • Adenosine receptor A2a
  • Adenosine receptor A2a and A3
  • Adenosine receptor A2b
  • Adenosine receptor A3
  • Homo sapiens phosphodiesterase 2A (PDE2A)
40 Ki 3 IC50 4 EC50
  • 2-CI Adenosine
  • 2-Chloroadenosine
  • 2-Chloroado
  • 2-[6-Amino-2-(2-cyclopentyl-ethylamino)-purin-9-yl]-5-hydroxymethyl-tetrahydro-furan-3,4-diol
  • CHEMBL285819
  • ALK tyrosine kinase receptor
  • ALK tyrosine kinase receptor (L1196M)
  • BDNF/NT-3 growth factors receptor
  • EML4-ALK
  • Focal adhesion kinase 1
  • High affinity nerve growth factor receptor
  • Leukocyte tyrosine kinase receptor
  • NT-3 growth factor receptor
  • PTK2B protein tyrosine kinase 2 beta (PTK2B)
  • Proto-oncogene tyrosine-protein kinase ROS
  • Tyrosine kinase non-receptor protein 2
  • Tyrosine-protein kinase FER
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fes/Fps
11 Ki 31 IC50
  • CHEMBL3286830
  • US10543199, Compound PF-06463922
  • US10780082, Compound PF-06463922
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Insulin-like growth factor I receptor
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
16 IC50
  • CHEMBL3288526
  • US9914707, I-4
  • Aldose reductase
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 15
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
13 Ki 1 IC50
  • 7-Methoxy-2-oxo-2H-chromene-4-carboxylic acid
  • CHEMBL12567
  • Bile salt export pump
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Envelope glycoprotein
  • Monoamine transporters; Norepininephrine & dopamine
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Norepinephrine Monoamine transporters
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • Transcriptional activator protein luxR
7 Ki 19 IC50 4 Kd
  • (1S,4S)-4-(3,4-dichlorophenyl)-N-methyl-1,2,3,4-tetrahydronaphthalen-1-amine
  • (1S-cis)-1,2,3,4-tetrahydro-4-(3,4-dichlorophenyl)-N-methyl-1-naphthalenamine
  • CHEMBL809
  • SERTRALINE
  • Choline acetylase
  • Ecto-5'-nucleotidase (e5'NT)
  • Ectonucleoside triphosphate diphosphohydrolase 1
  • Ectonucleoside triphosphate diphosphohydrolase 2
  • Ectonucleoside triphosphate diphosphohydrolase 8
  • Nucleoside triphosphate diphosphohydrolase 3
  • P2X purinoceptor 4
  • P2Y purinoceptor 1
  • Purinergic receptor P2Y11
  • Purinergic receptor P2Y12
  • Purinergic receptor P2Y2
  • Purinergic, P2X2
  • Pyrimidinergic receptor P2Y4
  • Pyrimidinergic receptor P2Y6
14 Ki 15 IC50 6 EC50
  • 1-Amino-4-{4-[4-chloro-6-(3-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid1-Amino-4-{4-[4-chloro-6-(4-sulfo-phenylamino)-[1,3,5]triazin-2-ylamino]-3-sulfo-phenylamino}-9,10-dioxo-9,10-dihydro-anthracene-2-sulfonic acid
  • CHEMBL223344
  • CID44285648
  • basilen blue
  • cibacron blue (mixer, meta and para isomers
  • 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3)
  • 5-lipoxygenase/FLAP
  • Aldo-keto reductase family 1 member C1
  • Aldo-keto reductase family 1 member C2
  • Aldo-keto reductase family 1 member C4 (AK1C4)
  • Aldo-keto reductase family member 1B10 (AKR1B10)
  • Aldose reductase (AR)
  • Arachidonate 15-lipoxygenase
  • Beta amyloid A4 protein
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Human immunodeficiency virus type 1 integrase
  • Integrase
  • Transthyretin
1 Ki 17 IC50 2 EC50
  • (E)-3-(3,4-Dihydroxy-phenyl)-acrylic acid phenethyl ester
  • (E)-phenethyl 3-(3,4-dihydroxyphenyl)acrylate
  • 3-(3,4-Dihydroxy-phenyl)-acrylic acid phenethyl ester
  • CAPE
  • CHEMBL319244
  • caffeic acid phenethyl ester
  • caffeic acid phenethylester
  • caffeic acid phenylethyl ester
  • caffeic acid phenylethylester
  • caffeic acidphenethylester
  • phenethyl 3-(3,4-dihydroxyphenyl)acrylate
  • phenethyl caffeate
  • 1,3-beta-glucan synthase component GLS2
  • ALK tyrosine kinase receptor
  • Dipeptidyl peptidase I
  • EML4-ALK
  • Epidermal growth factor receptor
  • Epidermal growth factor receptor (EGFR)(T790M/L858R)
  • Epidermal growth factor receptor (T790M)
  • Epidermal growth factor receptor erbB1
  • Epidermal growth factor receptor(L858R, T790M)
  • Insulin receptor
  • Insulin-like growth factor I receptor
  • Potassium voltage-gated channel subfamily H member 2
  • Replicase polyprotein 1ab
  • VHL/EGFR
5 Ki 107 IC50 12 EC50
  • AZD-9291
  • OSIMERTINIB
  • Osimertinib
  • US10085983, Compound AZD-9291
  • US10227342, Example 24
  • US9890168, Compound AZD-9291
  • ATP-binding cassette sub-family G member 2
  • Bile salt export pump (BSEP)
  • Cyclophilin A
  • Cyclophilin B (CypB)
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Multidrug resistance-associated protein 2 (MRP2)
  • P-glycoprotein 1
  • Peptidyl-prolyl cis-trans isomerase A
  • Peptidyl-prolyl cis-trans isomerase F, mitochondrial
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Solute carrier organic anion transporter family member 1B3 (OATP1B3)
11 IC50 6 Kd
  • CHEMBL3344501
  • US9566312, Compound 2.17.4
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrases; II & IX
37 Kd
  • CHEMBL3359181
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrases; II & IX
35 Kd
  • CHEMBL3359179
  • DNA topoisomerase I (Topo I)
  • DNA topoisomerase II
  • Dual specificity phosphatase Cdc25A
  • Dual specificity phosphatase Cdc25B
  • Epidermal growth factor receptor
  • Histone-lysine N-methyltransferase SETD7
  • Neuraminidase
  • Protein-tyrosine phosphatase 1
  • Protein-tyrosine phosphatase 1B
  • Pyruvate kinase (PKM2)
  • Pyruvate kinase PKLR
  • Sortase A (SrtA)
  • Sterol O-acyltransferase 1
  • Sterol O-acyltransferase 2
23 IC50
  • (R)-5,8-dihydroxy-2-(1-hydroxy-4-methylpent-3-enyl)naphthalene-1,4-dione
  • 5,8-Dihydroxy-2-((R)-1-hydroxy-4-methyl-pent-3-enyl)-[1,4]naphthoquinone
  • 5,8-Dihydroxy-2-(1-hydroxy-4-methyl-pent-3-enyl)-[1,4]naphthoquinone
  • CHEMBL9470
  • Shikonin
  • 1,3-beta-glucan synthase component GLS2
  • Aurora kinase B
  • Beta-hexosaminidase subunit beta (Hex B)
  • Cyclin-dependent kinase 1
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Phosphoehtnaolamine Methyltransferases 1 (PMT1)
  • Phosphoehtnaolamine Methyltransferases 2 (PMT2)
  • Platelet activating factor receptor
  • RAC-alpha serine/threonine-protein kinase
  • phosphatase Cdc25
14 IC50
  • 2-(((Hexadecyloxy)hydroxyphosphinyl)oxy)-N,N,N-trimethylethanaminium hydroxide
  • CHEMBL125
  • MILTEFOSINE
  • [2-(Hexadecyloxy-hydroxy-phosphoryloxy)-ethyl]-trimethyl-ammonium
  • hexadecyl 2-(trimethyl-lambda~5~-azanyl)ethyl hydrogen phosphate
  • hexadecyl 2-(trimethylammonio)ethyl phosphate
  • hexadecyloxy-2-trimethylammonioethylphosphorate
  • hexadecylphosphocholine
  • hexadecylphosphocholine, miltefosine
  • n-hexadecylphosphocholine
  • GRIA3
  • Glutamate receptor 1
  • Glutamate receptor ionotropic, AMPA 2
  • Glutamate receptor ionotropic, AMPA 4
  • Glutamate receptor ionotropic, kainate
  • Glutamate receptor ionotropic, kainate 1
  • Ionotropic glutamate receptor kainate 2/5
  • Metabotropic glutamate receptor
  • Metabotropic glutamate receptor 1
  • Metabotropic glutamate receptor 2
  • Metabotropic glutamate receptor 3
  • Metabotropic glutamate receptor 4 (mGlu4)
  • Metabotropic glutamate receptor 6 (mGlu6)
  • Metabotropic glutamate receptor 8
7 Ki 21 EC50
  • (S)-Amino-(3-hydroxy-isoxazol-5-yl)-acetic acid
  • (S)-Amino-(3-oxo-2,3-dihydro-isoxazol-5-yl)-acetic acid
  • CHEMBL30285
  • GABA A Alpha4Beta2Gamma2
  • GABA A receptor alpha-2/beta-2/gamma-2
  • GABA A receptor alpha-3/beta-2/gamma-2
  • GABA A receptor alpha-6/beta-2/gamma-2
  • GABA receptor alpha-1/beta-3/gamma-2 subunit
  • GABA receptor alpha-2/beta-3/gamma-2 subunit
  • GABA receptor alpha-3/beta-3/gamma-2 subunit
  • GABA receptor alpha-4/beta-3/gamma-2 subunit
  • GABA receptor alpha-5/beta-3/gamma-2 subunit
  • GABA receptor alpha-6/beta-3/gamma-2 subunit
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Gamma-aminobutyric acid receptor subunit alpha-2/beta-2
  • Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A))
  • Gamma-aminobutyric acid receptor subunit alpha-5/beta-3
25 Ki
  • 8-Chloro-3-methoxymethyl-5-methyl-4,5-dihydro-2,5,10b-triaza-benzo[e]azulen-6-one
  • CHEMBL45346
  • Adenosine receptor A3
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Potassium voltage-gated channel subfamily H member 2
  • Sphingosine 1-phosphate receptor 1
  • Sphingosine 1-phosphate receptor 1 (S1P1)
  • Sphingosine 1-phosphate receptor 2
  • Sphingosine 1-phosphate receptor 3
  • Sphingosine 1-phosphate receptor 4
  • Sphingosine 1-phosphate receptor 5
  • Sphingosine-1-phosphate receptor 1
9 IC50 10 EC50
  • CHEMBL3358920
  • Bromodomain testis-specific protein
  • Bromodomain-containing protein 4
  • Casein kinase I isoform delta
  • Casein kinase I isoform epsilon
  • MAP kinase p38
  • Mitogen-activated protein kinase 11
  • Mitogen-activated protein kinase 14
  • Tau-tubulin kinase 1
  • Tau-tubulin kinase 2
  • Tyrosinase
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • p38 MAP kinase alpha/beta
25 IC50 1 Kd
  • CHEBI:79090
  • SB-202190
  • US10865384, Compound SB202190
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2J2
  • Cytochrome P450 3A
  • DNA Gyrase
  • DNA topoisomerase II
  • Multidrug resistance protein mdtK
  • Multidrug resistance-associated protein 4
  • Topoisomerase IV subunit A
2 Ki 12 IC50 1 Kd
  • (NFLX)1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
  • (norfloxacin)1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
  • 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4,4a,8a-tetrahydro-quinoline-3-carboxylic acid (norfloxacin)
  • 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid
  • 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid (Norfloxacin)
  • 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid(1-norfloxacin)
  • 1-Ethyl-6-fluoro-4-oxo-7-piperazin-1-yl-1,4-dihydro-quinoline-3-carboxylic acid(Norfloxacin)
  • 1-ethyl-6-fluoro-4-oxo-7-(piperazin-1-yl)-1,4-dihydroquinoline-3-carboxylic acid
  • 1-ethyl-6-fluoro-7-hexahydro-1-pyrazinyl-4-oxo-1,4-dihydro-3-quinolinecarboxylic acid
  • CHEMBL9
  • Chibroxin
  • MK-366
  • NORFLOXACIN
  • Noroxin
  • 10 kDa chaperonin
  • 60 kDa chaperonin
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Glycine receptor subunit alpha-1
  • HSP60/HSP10
  • Multidrug resistance-associated protein 4
  • Retinoic acid receptor RXR-alpha/Retinoic acid receptor beta
  • Retinoic acid receptor RXR-alpha/gamma
  • Retinoic acid receptor alpha/Retinoid X receptor alpha
  • Retinoid X receptor gamma/retinoic acid receptor alpha
  • Retinoid receptor
  • Thiosulfate sulfurtransferase
6 Ki 9 IC50 4 EC50
  • 6-(3-(1-Adamantyl)-4-methoxyphenyl)-2-naphthoic acid
  • 6-(3-adamantan-1-yl-4-methoxyphenyl)naphthalene-2-carboxylic acid
  • ADAPALENE
  • CHEMBL1265
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Glutathione S-transferase (GST)
  • Glutathione peroxidase 1 (GPx)
  • Glutathione reductase (GR)
  • Multidrug resistance-associated protein 4
  • Oligopeptide transporter small intestine isoform
  • Oligopeptide transporter, kidney isoform
  • Solute carrier family 22 member 11
  • Solute carrier family 22 member 6
  • Solute carrier family 22 member 8
11 Ki 9 IC50
  • (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-3-(2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-[1,2,4]triazin-3-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R)-7-{2-(2-Amino-thiazol-4-yl)-2-[(Z)-methoxyimino]-acetylamino}-3-(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-[1,2,4]triazin-3-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R,)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-ylthio)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • (6R,7R,Z)-7-(2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-((2-methyl-5,6-dioxo-1,2,5,6-tetrahydro-1,2,4-triazin-3-ylthio)methyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid
  • 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-3-(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-[1,2,4]triazin-3-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid (Ceftriaxone)
  • 7-[2-(2-Amino-thiazol-4-yl)-2-methoxyimino-acetylamino]-3-(6-hydroxy-2-methyl-5-oxo-2,5-dihydro-[1,2,4]triazin-3-ylsulfanylmethyl)-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-ene-2-carboxylic acid(Ceftriaxone)
  • CHEMBL161
  • ceftriaxone
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 7
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Dopamine receptor
  • Histamine H1 receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma intracellular receptor 2
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
16 Ki
  • CHEMBL3321791
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Cytochrome P450 19A1
  • Dipeptidyl peptidase 3
  • Leukotriene A4 hydrolase
  • Multidrug resistance-associated protein 4
  • Myeloperoxidase (MPO)
  • Prostaglandin E synthase/G/H synthase 2
  • Prostaglandin G/H synthase (Cyclooxygenase-2)
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Serum albumin
10 Ki 36 IC50
  • CHEMBL56367
  • nimesulide
  • PKC alpha and beta-2
  • Protein Kinase C, alpha
  • Protein kinase C alpha type
  • Protein kinase C delta
  • Protein kinase C delta type
  • Protein kinase C eta
  • Protein kinase C gamma
  • Protein kinase C theta type
  • Protein kinase C, PKC; classical/novel
  • Protein kinase C, epsilon
  • Protein kinase C, eta
  • Protein kinase C, gamma
  • Proto-oncogene vav
  • Transient receptor potential cation channel subfamily V member 4
32 Ki 61 Kd 1 EC50
  • (1aR,1bS,4aR,7aS,7bS,8R,9R,9aS)-4a,7b-dihydroxy-3-(hydroxymethyl)-1,1,6,8-tetramethyl-5-oxo-1,1a,1b,4,4a,5,7a,7b,8,9-decahydro-9aH-cyclopropa[3,4]benzo[1,2-e]azulene-9,9a-diyl dibutanoate
  • CHEMBL27768
  • PDBu
  • phorbol 12,13-dibutanoate
  • phorbol 12,13-dibutyrate
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 7
  • ADRA1B
  • Adrenergic alpha1B
  • Adrenergic receptor alpha-2
  • Alpha adrenergic receptor 1A and 1B
  • Alpha-1 adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Cerebral cortex alpha adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
35 Ki 4 IC50 4 Kd 2 EC50
  • (R)-5-(2-((2-(2-ethoxyphenoxy)ethyl)amino)propyl)-2-methoxybenzenesulfonamide
  • 5-[(2R)-2-{[2-(2-ethoxyphenoxy)ethyl]amino}propyl]-2-methoxybenzenesulfonamide
  • 5-[2-[2-(2-ethoxyphenoxy)ethylamino]propyl]-2-methoxy-benzenesulfonamide
  • CHEMBL836
  • TAMSULOSIN
  • ADRA1B
  • Adrenergic alpha1B
  • Adrenergic receptor alpha-2
  • Alpha adrenergic receptor 1A and 1B
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(2) dopamine receptor
  • Dopamine D1 receptor
  • HTR1F
  • Serotonin 2a (5-HT2a) receptor
16 Ki 4 Kd
  • 2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione
  • 2-[2-((3aR,9bR)-6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,6-triaza-fluorene-1,3-dione
  • 2-[2-(6-Methoxy-1,3,3a,4,5,9b-hexahydro-benzo[e]isoindol-2-yl)-ethyl]-4H-9-thia-2,4,5-triaza-fluorene-1,3-dione
  • A-131701
  • CHEMBL40650
  • 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3)
  • Aldo-keto reductase family 1 member C1
  • Aldo-keto reductase family 1 member C2
  • Aldo-keto-reductase family 1 member C3
  • Androgen Receptor
  • Androgen receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Glucocorticoid receptor
  • Mineralocorticoid receptor
  • Multidrug resistance-associated protein 4
  • Progesterone receptor
  • Testis-specific androgen-binding protein
18 Ki 25 IC50 1 Kd 24 EC50
  • (6alpha)-17-(Acetyloxy)-6-methylpreg-4-ene-3,20-dione
  • (6alpha)-6-methyl-3,20-dioxopregn-4-en-17-yl acetate
  • 17-Acetoxy-6alpha-methylprogesterone
  • 17alpha-Hydroxy-6alpha-methylprogesterone acetate
  • 6-alpha-Methyl-17-alpha-acetoxyprogesterone
  • 6-alpha-Methyl-17-alpha-hydroxyprogesterone acetate
  • 6alpha-Methyl-17-acetoxy progesterone
  • 6alpha-Methyl-17alpha-hydroxyprogesterone acetate
  • 6alpha-Methyl-4-pregnene-3,20-dion-17alpha-ol acetate
  • MEDROXYPROGESTERONE
  • Medroxyacetate progesterone
  • Medroxyprogesterone 17-acetate
  • Methylacetoxyprogesterone
  • Metigestrona
  • US9271961, MPA
  • medroxyprogesterone acetate
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2J2
  • Cytochrome P450 3A
  • Endo-beta-N-acetylglucosaminidase
  • Fatty acid synthase
  • Multidrug resistance-associated protein 4
  • Potassium-transporting ATPase alpha chain 1/beta chain
1 Ki 17 IC50
  • A-65006
  • AG-1749
  • CHEBI:6375
  • LANSOPRAZOLE
  • Lansoprazole
  • Prevacid
  • Prevacid 24hr
  • Prevacid Delayed Release
  • Prevacid Solutab
  • Prevacid iv
  • Angiopoietin-1 receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • BDNF/NT-3 growth factors receptor
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 3A
  • Fibroblast growth factor receptor 1
  • High affinity nerve growth factor receptor
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase PLK2
  • Serine/threonine-protein kinase PLK3
  • Serine/threonine-protein kinase PLK4
  • Tyrosine-protein kinase receptor FLT3
2 Ki 23 IC50 12 EC50
  • CHEMBL3408947
  • US10358436, Example A185
  • US9907800, Example A185
  • Interleukin-1 receptor-associated kinase 1
  • Mitogen-activated protein kinase kinase kinase 2
  • Mitotic checkpoint serine/threonine-protein kinase BUB1
  • Potassium voltage-gated channel subfamily H member 2
  • Proto-oncogene tyrosine-protein kinase ROS
  • Serine/threonine-protein kinase 2
  • Serine/threonine-protein kinase PAK 4
  • Serine/threonine-protein kinase PAK6
  • Serine/threonine-protein kinase PAK7
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • Tyrosine-protein kinase receptor UFO
12 IC50 13 Kd
  • CHEMBL3416026
  • US9290481, 1.1
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Adrenergic receptor alpha
  • Adrenergic receptor alpha-2
  • Alpha adrenergic receptor 1A and 1B
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Muscarinic acetylcholine receptor M5
  • Sigma intracellular receptor 2
  • Sigma non-opioid intracellular receptor 1
21 Ki 8 IC50
  • 7-[4-(4-Chloro-phenyl)-piperazin-1-ylmethyl]-4H-benzo[1,4]oxazin-3-one
  • CHEMBL346389
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
9 Ki 13 IC50
  • 5-Methyl-6-trifluoromethyl-2,3-dihydro-indole-1-carboxylic acid [6-(2-methyl-pyridin-3-yloxy)-pyridin-3-yl]-amide
  • 5-methyl-N-(6-(2-methylpyridin-3-yloxy)pyridin-3-yl)-6-(trifluoromethyl)indoline-1-carboxamide
  • CHEMBL14460
  • SB-243213
  • Androgen Receptor
  • Baculoviral IAP repeat-containing protein 2/Estrogen receptor
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Estradiol receptor beta (ERβ)
  • Estrogen receptor
  • Glucocorticoid receptor
  • Mineralocorticoid receptor
  • Progesterone receptor
  • Sodium-dependent dopamine transporter
1 Ki 20 IC50 3 EC50
  • CHEMBL3581693
  • 5-hydroxytryptamine receptor 1A (5HT1A)
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • Adrenergic alpha1B
  • Alpha adrenergic receptor 1A and 1B
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Histamine H1 receptor
  • Histamine H2 Receptor
  • Voltage-gated L-type calcium channel
23 Ki
  • (4S,5S)-4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxazolidine-3-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
  • (4S,5S)-4-(3,4-difluorophenyl)-N-(3-(4-(4-fluorophenyl)piperidin-1-yl)propyl)-5-methyl-2-oxooxazolidine-3-carboxamide
  • 4-(3,4-Difluoro-phenyl)-5-methyl-2-oxo-oxazolidine-3-carboxylic acid {3-[4-(4-fluoro-phenyl)-piperidin-1-yl]-propyl}-amide
  • CHEMBL96467
  • SNAP-7915
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Alpha-1A adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • HTR1D
  • Histamine H1 receptor
  • Muscarinic acetylcholine receptor M2
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • adrenergic Alpha2
15 Ki 1 EC50
  • 1-(4-Dipropylamino-1,3,4,5-tetrahydro-benzo[cd]indol-6-yl)-ethanone
  • CHEMBL276031
  • LY 293284
  • LY-293284
  • LY-293384
  • Activin receptor type-1
  • Cytoplasmic tyrosine-protein kinase BMX
  • LIM domain kinase 1
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine kinase non-receptor protein 2
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
17 IC50 2 EC50
  • CHEMBL3586447
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adrenergic alpha1B
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Serotonin (5-HT) receptor
59 Ki 7 IC50 1 Kd
  • (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidin-1-ylsulfonyl)phenol
  • (R)-3-(2-(2-(4-methylpiperidin-1-yl)ethyl)pyrrolidine-1-sulfonyl)phenol
  • 3-{(R)-2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol
  • 3-{(S)-2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol
  • 3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol
  • 3-{2-[2-(4-Methyl-piperidin-1-yl)-ethyl]-pyrrolidine-1-sulfonyl}-phenol (SB-269970)
  • CHEMBL282199
  • SB-269970
  • PTGER3
  • Prostaglandin D Synthase
  • Prostaglandin E2 receptor
  • Prostaglandin E2 receptor EP1 subtype (EP1)
  • Prostaglandin E2 receptor EP2 subtype
  • Prostaglandin E2 receptor EP4 subtype
  • Prostaglandin F2-alpha receptor
  • Prostaglandin Transporter
  • Prostanoid EP1 Receptor
  • Prostanoid EP2 Receptor
  • Prostanoid EP2 receptor
  • Prostanoid EP3 Receptor
  • Prostanoid EP4 Receptor
  • Prostanoid IP receptor
16 Ki 2 EC50
  • 7-{(1R,3R)-3-Hydroxy-2-[(E)-(S)-4-hydroxy-4-(1-propyl-cyclobutyl)-but-1-enyl]-5-oxo-cyclopentyl}-heptanoic acid methyl ester
  • BUTAPROST
  • Butaprost (Methyl Ester)
  • CHEMBL432522
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Multidrug resistance-associated protein 4
  • Prostanoid EP1 Receptor
  • Prostanoid EP1 receptor
  • Prostanoid EP2 Receptor
  • Prostanoid EP2 receptor
  • Prostanoid EP3 Receptor
  • Prostanoid EP3 receptor
  • Prostanoid EP4 Receptor
  • Prostanoid EP4 receptor
  • Prostanoid IP receptor
  • Solute carrier organic anion transporter family member 2B1
20 Ki 6 IC50 5 EC50
  • (11alpha,13E,15S)-11,15-dihydroxy-9-oxoprost-13-en-1-oic acid
  • (13E,15S)-11alpha,15-dihydroxy-9-oxoprost-13-en-1-oic acid
  • 11alpha,15alpha-dihydroxy-9-oxo-13-trans-prostenoic acid
  • ALPROSTADIL
  • CHEMBL495
  • PGE-1
  • PGE1
  • prostaglandin E1
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Carbonic Anhydrase III
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 2
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase V
  • Carbonic anhydrases; II & IX
  • Multidrug resistance-associated protein 4
  • POU domain, class 5, transcription factor 1
12 Ki 8 IC50
  • CHEBI:4975
  • FAMOTIDINE
  • Famotidine
  • Fluxid
  • MK-208
  • Pepcid
  • Pepcid Ac
  • Pepcid Rpd
  • Adrenergic receptor alpha-1
  • Beta-1 adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M2
  • Nociceptin receptor
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Voltage-gated L-type calcium channel
17 IC50
  • 8-(3-Phenoxy-benzyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
  • CHEMBL115280
  • Carbonic Anhydrase III
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 15
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
19 Ki
  • Adamantane-1-carboxylic acid (5-sulfamoyl-[1,3,4]thiadiazol-2-yl)-amide
  • CHEMBL108971
  • 5-hydroxytryptamine receptor 1A (5HT1A)
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 3A
  • Alpha-2A adrenergic receptor
  • D(2) dopamine receptor
  • Dopamine D1 receptor
  • Glycine receptor alpha-4 chain
  • Histamine H1 receptor
  • NMDA receptor subunit 2C (GluN2C)
  • Neurokinin 1 receptor
  • Neurokinin 2 receptor
  • Neuromedin-K receptor
  • Sigma non-opioid intracellular receptor 1
  • Sigma-1 receptor
14 Ki 12 IC50
  • 1'-benzyl-3-methoxyspiro[3,4-dihydro-1H-isochromene-1,4'-(hexahydropyridine)]
  • 1'-benzyl-3-methoxyspiro[isochroman-1,4'-piperidine]
  • CHEMBL141209
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • CDGSH iron-sulfur domain-containing protein 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Liver fatty acid binding protein (rat L-FABP)
  • Multidrug resistance-associated protein 4
  • Organic anion-transporting polypeptide 1D1 (Oatp1d1)
  • Peroxisome proliferator-activated receptor
  • Peroxisome proliferator-activated receptor alpha (PPAR alpha)
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Solute carrier organic anion transporter family member 1B3 (OATP1B3)
  • Transthyretin
4 Ki 15 IC50 1 Kd 5 EC50
  • 2,2-Dimethyl-5-(2,5-dimethylphenoxy)valeriansaeure
  • 2,2-Dimethyl-5-(2,5-xylyloxy)valeriansaeure
  • 2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid
  • 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid
  • CHEMBL457
  • GEMFIBROZIL
  • Angiopoietin-1 receptor
  • Cyclin-dependent kinase 1
  • Hepatocyte growth factor receptor
  • Insulin receptor
  • PDGFR-beta/Platelet-derived growth factor receptor alpha
  • Protein kinase C (PKC)
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase ZAP-70
  • Vascular endothelial growth factor receptor 2
14 IC50
  • (R)-7-[4-(4-Methyl-piperazin-1-yl)-cyclohexyl]-5-(4-phenoxy-phenyl)-7H-pyrrolo[2,3-d]pyrimidin-4-ylamine
  • CHEMBL47203
  • Dual specificity mitogen-activated protein kinase kinase 1
  • Dual specificity mitogen-activated protein kinase kinase 3
  • Dual specificity mitogen-activated protein kinase kinase 6
  • Epidermal growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 8
  • PDGFR-beta/Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
17 IC50
  • 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-nitro-phenyl)-amide
  • 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-nitro-phenyl)-amide(KN1022)
  • CHEMBL99743
  • Dual specificity mitogen-activated protein kinase kinase 1
  • Dual specificity mitogen-activated protein kinase kinase 3
  • Dual specificity mitogen-activated protein kinase kinase 6
  • Epidermal growth factor receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 8
  • PDGFR-beta/Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
15 IC50
  • 4-(6,7-Dimethoxy-quinazolin-4-yl)-piperazine-1-carboxylic acid (4-bromo-phenyl)-amide
  • CHEMBL323336
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 9
  • DNA excision repair protein ERCC-5
  • Flap endonuclease 1
  • Genome polyprotein
  • GlcB
  • Hepatitis C virus NS5B RNA-dependent RNA polymerase
  • Human immunodeficiency virus type 1 integrase
  • Human immunodeficiency virus type 1 reverse transcriptase
  • PA/PB1
  • Polymerase acidic protein
  • Protein-tyrosine phosphatase 1B
5 Ki 23 IC50 1 EC50
  • (Z)-2-hydroxy-4-oxo-4-phenyl-but-2-enoic acid
  • 2-Hydroxy-4-oxo-4-phenyl-but-2-enoic acid
  • 2-Hydroxy-4-oxo-4-phenyl-but-2-enoic acid (0.25H2O)
  • CHEMBL16326
  • CHEMBL19332
  • CHEMBL467389
  • Sacchettini_CTRL
  • Angiopoietin-1 receptor
  • Cyclin-dependent kinase 1
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Insulin-like growth factor I receptor
  • Macrophage colony-stimulating factor 1 receptor (CSF1R)
  • Macrophage-stimulating protein receptor
  • Mast/stem cell growth factor receptor Kit
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine-protein kinase ABL1
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
15 IC50
  • CHEMBL347537
  • N-(3-Isoquinolin-4-yl-phenyl)-2-[(pyridin-4-ylmethyl)-amino]-benzamide
  • Alpha-chymotrypsin
  • Calpain 1
  • Calpain1/2
  • Caspase-1
  • Cathepsin B
  • Coagulation factor VII
  • Coagulation factor X
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Prothrombin
  • Trypsin-1
15 IC50
  • 2-(4-Fluoro-benzenesulfonylamino)-N-(1-formyl-3-methyl-butyl)-3-methyl-butyramide
  • CHEMBL168471
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adrenergic alpha1B
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • HTR6
  • Serotonin (5-HT) receptor
23 Ki
  • CHEMBL329383
  • N-(2,5-Dibromo-3-fluoro-phenyl)-4-methoxy-3-piperazin-1-yl-benzenesulfonamide
  • N-(2,5-dibromo-3-fluorophenyl)-4-methoxy-3-(piperazin-1-yl)benzenesulfonamide
  • SB-357134
  • α-Carbonic anhydrase (αCA)
  • β-Carbonic anhydrase (βCA)
  • Alpha-carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonic Anhydrase XIII
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 7
  • Gamma-carbonic anhydrase
  • Histone-lysine N-methyltransferase EHMT1
  • Protein G9a (G9a)
36 Ki 2 IC50
  • CHEMBL114503
  • lambda~4~-selenium oxide; disodium
  • sodium selenate
  • sodium selenate(VI)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Hepatocyte growth factor receptor
  • Pancreatic lipase
13 Ki 2 IC50
  • CHEMBL3628211
  • p-Hydroxyphenylethyl p-coumarate (17)
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Dopamine receptor
  • Metabotropic glutamate receptor
  • Muscarinic acetylcholine receptor
  • SLC6A3
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
15 Ki
  • 6-Methoxy-1-methyl-4,9-dihydro-3H-beta-carboline
  • 6-methoxy-harmalan
  • CHEMBL338115
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Dual specificity mitogen-activated protein kinase kinase 1
  • Dual specificity mitogen-activated protein kinase kinase 2
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Ribosomal protein S6 kinase (P70S6K)
  • Ribosomal protein S6 kinase alpha 1
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase HCK
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
20 IC50
  • CHEMBL3753341
  • Bromodomain testis-specific protein
  • Bromodomain-containing protein 4
  • CDK2/CycE
  • CDK7/Cyclin H/MNAT1
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 4
  • Cyclin-dependent kinase 9
  • Cyclin-dependent-like kinase 5
46 IC50
  • DINACICLIB
  • Dinaciclib
  • MK-7965
  • SCH-727965
  • Acetylcholine receptor
  • Acetylcholine receptor protein alpha chain/beta chain/delta chain /gamma chain
  • Acetylcholine receptor protein alpha/beta/delta/gamma chain
  • Neuronal acetylcholine receptor
  • Neuronal acetylcholine receptor Alpha-2/Beta-4
  • Neuronal acetylcholine receptor Alpha-3/Beta-2
  • Neuronal acetylcholine receptor Alpha-3/Beta-4
  • Neuronal acetylcholine receptor Alpha-4/Beta-2
  • Neuronal acetylcholine receptor protein alpha-2/beta-2 subunit
  • Neuronal acetylcholine receptor protein alpha-3/beta-2 subunit
  • Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit
  • Neuronal acetylcholine receptor protein alpha-4/beta-4 subunit
  • Neuronal acetylcholine receptor protein alpha-7 subunit
  • Neuronal acetylcholine receptor; alpha3/beta4
36 Ki 1 IC50 10 EC50
  • (-)-cytisine
  • (1R,5S)-1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one
  • (1R,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one
  • (1R,9S)-7,11-diazatricyclo[7.3.1.02,7]trideca-2,4-dien-6-one
  • (1R,9S)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one
  • (1S,9R)-7,11-diazatricyclo[7.3.1.0~2,7~]trideca-2,4-dien-6-one
  • 1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one
  • 1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one (cytisine)
  • CHEMBL497939
  • Cytisine1,2,3,4,5,6-Hexahydro-1,5-methano-pyrido[1,2-a][1,5]diazocin-8-one
  • cytisine
  • Acetylcholinesterase
  • Alkaline phosphatase placental-like
  • Alkaline phosphatase, tissue-nonspecific isozyme
  • Alpi
  • Beta lactamase
  • Beta-secretase 1
  • CAMK2A
  • Cyclooxygenase
  • Human immunodeficiency virus type 1 integrase
  • Intestinal alkaline phosphatase
  • M.SssI methyltransferase
  • Multidrug resistance protein CDR1
  • Serine/threonine-protein kinase 33
  • Toll-like receptor 9
14 IC50 1 EC50
  • (1E,4Z,6E)-5-Hydroxy-1-(4-hydroxy-3-methoxy-phenyl)-7-(4-hydroxy-phenyl)-hepta-1,4,6-trien-3-one
  • (1E,6E)-1-(4-Hydroxy-3-methoxy-phenyl)-7-(4-hydroxy-phenyl)-hepta-1,6-diene-3,5-dione
  • 1-(4-hydroxy-3-methoxyphenyl)-7-(4-hydroxyphenyl)-1,6-heptadiene-3,5-dione
  • 5-hydroxy-7-(4-hydroxy-3-methoxyphenyl)-1-(4-hydroxyphenyl)hepta-1,4,6-trien-3-one
  • CHEMBL179512
  • cid_5324476
  • curcumin II
  • demethoxycurcumin
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • ADAMTS1
  • Collagenase 3
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Interstitial collagenase
  • Matrix metalloproteinase 12
  • Matrix metalloproteinase 14
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Stromelysin-1
  • Tumor necrosis factor
30 IC50
  • (2R,3R)-1-[4-(2-Chloro-4-fluoro-benzyloxy)-benzenesulfonyl]-3-hydroxy-3-methyl-piperidine-2-carboxylic acid hydroxyamide
  • CHEMBL187092
  • 1,3-beta-glucan synthase component GLS2
  • Casein kinase II subunit alpha
  • Casein kinase II subunit alpha'
  • Death-associated protein kinase 2
  • Death-associated protein kinase 3
  • Dual specificity tyrosine-phosphorylation-regulated kinase 4
  • Dual-specificity tyrosine-phosphorylation regulated kinase 1A
  • Dual-specificity tyrosine-phosphorylation regulated kinase 2
  • Dual-specificity tyrosine-phosphorylation regulated kinase 3
  • Dual-specificity tyrosine-regulated kinases 1B
  • Homeodomain-interacting protein kinase 1
  • Homeodomain-interacting protein kinase 2 (HIPK2)
  • Homeodomain-interacting protein kinase 3
  • Homeodomain-interacting protein kinase 4
14 IC50 2 Kd
  • CHEMBL3103192
  • Adenosine Receptors A2a (A2a)
  • Adenosine receptor
  • Adenosine receptor A1
  • Adenosine receptor A2a
  • Adenosine receptor A2a and A3
  • Adenosine receptor A2b
  • Adenosine receptor A3
  • Adenosine receptors; A2a & A2b
  • Amine oxidase [flavin-containing] B
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
56 Ki 9 IC50
  • 8-(3,4-dimethoxystyryl)-1,3-diethyl-7-methyl-1H-purine-2,6(3H,7H)-dione
  • 8-[(E)-2-(3,4-Dimethoxy-phenyl)-vinyl]-1,3-diethyl-7-methyl-3,7-dihydro-purine-2,6-dione
  • 8-[2-(3,4-dimethoxy-phenyl)-vinyl]-1,3-diethyl-7-methyl-3,9-dihydro-purine-2,6-dione
  • CHEMBL431770
  • istradefylline
  • 14-alpha sterol demethylase
  • 14-alpha sterol demethylase Cyp51A
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 11B1
  • Cytochrome P450 11B2
  • Cytochrome P450 17A1
  • Cytochrome P450 19A1
  • Cytochrome P450 2C9
  • Cytochrome P450 3A
  • Lanosterol 14-alpha demethylase
  • Multidrug resistance-associated protein 4
  • Sterol 14-alpha demethylase (CYP51)
18 IC50 4 Kd
  • 4-(4-(4-(4-(((3R,5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2H-1,2,4-triazol-3(4H)-one
  • 4-(4-(4-(4-(((5R)-5-((1H-1,2,4-triazol-1-yl)methyl)-5-(2,4-difluorophenyl)-tetrahydrofuran-3-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2-((2S,3S)-2-hydroxypentan-3-yl)-2H-1,2,4-triazol-3(4H)-one
  • 4-[4-(4-{4-[(R)-5-(2,4-difluoro-phenyl)-5-(4,5-dihydro-[1,2,4]triazol-1-ylmethyl)-tetrahydro-furan-3-ylmethoxy]-phenyl}-piperazin-1-yl)-phenyl]-2-((1S,2S)-1-ethyl-2-hydroxy-propyl)-2,4-dihydro-[1,2,4]triazol-3-one
  • CHEMBL1397
  • Noxafil
  • POSACONAZOLE
  • pasaconazole
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
22 IC50
  • CHEMBL3823861
  • US10294227, Code 221
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
22 IC50
  • CHEMBL3823212
  • US10294227, Code 109
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
22 IC50
  • CHEMBL3823849
  • US10294227, Code 112
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
22 IC50
  • CHEMBL3822591
  • US10294227, Code 113
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • Adrenergic alpha1B
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Dopamine receptor
  • Histamine H1 receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
35 Ki
  • 4-(3-(4-chlorophenyl)-3-hydroxy-8-aza-bicyclo[3.2.1]octan-8-yl)-1-(4-fluorophenyl)butan-1-one
  • 4-[3-(4-Chloro-phenyl)-3-hydroxy-8-aza-bicyclo[3.2.1]oct-8-yl]-1-(4-fluoro-phenyl)-butan-1-one
  • 4-[3-(4-Chlorophenyl)-3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl]-1-(4-fluorophenyl)butan-1-one
  • CHEMBL210578
  • Alpha-(1,3)-fucosyltransferase VII
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Tyrosinase
14 Ki 2 IC50
  • 3,5-Dimethoxy-4-hydroxybenzoic acid
  • 4-hydroxy-3,5-dimethoxybenzoic acid
  • CHEMBL1414
  • Syringic acid
  • 72 kDa type IV collagenase
  • ADAM17
  • Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Disintegrin and metalloproteinase domain-containing protein 33
  • Disintegrin and metalloproteinase domain-containing protein 8
  • Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)
  • Interstitial collagenase
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Receptor tyrosine-protein kinase erbB-2
  • Stromelysin-1
22 IC50
  • (6S,7S)-methyl 7-(hydroxycarbamoyl)-6-(4-phenyl-1,2,3,6-tetrahydropyridine-1-carbonyl)-5-azaspiro[2.5]octane-5-carboxylate
  • CHEMBL434567
  • methyl (6S,7S)-7-[(hydroxyamino)carbonyl]-6-[(4-phenyl-3,6-dihydropyridin-1(2H)-yl)carbonyl]-5-azaspiro[2.5]octane-5-carboxylate
  • Aurora kinase A/Targeting protein for Xklp2
  • Cyclin-dependent kinase 1
  • MAP kinase-activated protein kinase 2
  • MAP/microtubule affinity-regulating kinase 2
  • Mitogen-activated protein kinase 1
  • Protein kinase C delta type
  • Protein kinase C, gamma
  • Proto-oncogene tyrosine-protein kinase Src
  • RAC-alpha serine/threonine-protein kinase
  • Serine/threonine-protein kinase AKT
  • Serine/threonine-protein kinase CHK2
  • Serine/threonine-protein kinase Chk1/2
  • Serine/threonine-protein kinase Sgk1
  • cAMP-dependent protein kinase (PKA)
1 Ki 17 IC50 3 EC50
  • 3-(4'-HYDROXYBIPHENYL-4-YL)-N-(4-HYDROXYCYCLOHEXYL)-1,4-DIHYDROINDENO[1,2-C]PYRAZOLE-6-CARBOXAMIDE
  • 3-(4'-hydroxy-biphenyl-4-yl)-1,4-dihydro-indeno[1,2-c]pyrazole-6-carboxylic acid (trans-4-hydroxycyclohexyl)-amide
  • 3-(4'-hydroxybiphenyl-4-yl)-N-((1r,4r)-4-hydroxycyclohexyl)-1,4-dihydroindeno[1,2-c]pyrazole-6-carboxamide
  • 3-(4'-hydroxybiphenyl-4-yl)-N-(trans-4-hydroxycyclohexyl)-2,4-dihydroindeno[1,2-c]pyrazole-6-carboxamide
  • CHEMBL438485
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Fibroblast growth factor receptor 1
  • Proto-oncogene tyrosine-protein kinase Src
  • Ras-related protein Rab-7L1
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
  • Vascular endothelial growth factor receptor 2
9 Ki 5 IC50
  • CHEMBL3893914
  • 5-hydroxytryptamine receptor 3A
  • CHRM5
  • Cytochrome P450 1A
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
  • Voltage-gated calcium channel
8 IC50 12 EC50
  • CHEMBL3963788
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