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Compounds Sorted by Binding Targets per Compound

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30   31   32   33   34   35   36   37   38   39   40   41   42   43   44   45   46   47   48   49   50   51   52   53   54   55   
56   57   58   59   60   61   62   63   64   65   66   67   68   69   70   73   74   75   76   77   79   81   84   86   89   95   
96   100   108   109   120   124   130   137   143   154   156   168   186   224   240   259   276   278   284   303   
304   310   315   323   339   369   370   371   372   373   374   375   376   377   378   380   381   383   384   
385   386   388   389   390   391   392   393   394   395   397   398   401   403   404   406   408   418   427   
429   443   447   515   
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
  • 5'-AMP-activated protein kinase subunit beta-1
  • ALK1
  • ALK2
  • ALK3
  • ALK4
  • ALK5
  • Activin receptor type-1
  • Activin receptor type-1B
  • Activin receptor-like kinase 3 (ALK-3)
  • Bone morphogenetic protein 4
  • Bone morphogenetic protein receptor type-1B (BMPR1B) aa 168-495
  • Bone morphogenetic protein receptor type-2
  • Serine/threonine-protein kinase receptor R3
  • TGF-beta receptor type II
  • TGF-beta receptor type-1
15 IC50
  • LDN-212854
  • Astrosclerin-3
  • Carbonic Anhydrase III
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 15
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
25 Ki
  • 2-N-(4-amino-3-chloro-5-fluorobenzene)-1,3,4-thiadiazole-2,5-disulfonamide
  • 5-{[(4-amino-3-chloro-5-fluorophenyl)sulfonyl]amino}-1,3,4-thiadiazole-2-sulfonamide
  • CHEMBL71611
  • aminobenzolamide 18
  • 1,3-beta-glucan synthase component GLS2
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • GABA A receptor alpha-2/beta-2/gamma-2
  • GABA receptor alpha-1/beta-3/gamma-2 subunit
  • GABA receptor alpha-3/beta-3/gamma-2 subunit
  • GABA receptor alpha-5/beta-3/gamma-2 subunit
  • Gamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2
  • Neurokinin 2 receptor
  • Sodium channel protein type 5 subunit alpha
7 Ki 10 IC50
  • US8952008, 4
  • CDK2/CycE
  • CDK4/CDK1
  • CDK4/Cyclin D3
  • CDK6/CycD3
  • CDK7/Cyclin H/MNAT1
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 4
  • Cyclin-dependent kinase 6
  • Protein cereblon/Cyclin-dependent kinase 2
33 IC50
  • 7-cyclopentyl-N,N-dimethyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-7H-pyrrolo[2,3-d]pyrimidine-6-carboxamide
  • Kisqali
  • LEE011
  • Ribociclib
  • US10570141, Comparative Example 1
  • US8962630, 74
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDK2/Cyclin A1
  • CDK3/E
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 3 (CDK3)
  • Cyclin-dependent kinase 6
  • Cyclin-dependent kinase 7
  • Cyclin-dependent kinase 9
  • Cyclin-dependent-like kinase 5
  • Glycogen synthase kinase-3
  • Interleukin-1 receptor-associated kinase 1
15 IC50
  • US9067888, 33
  • Cereblon/Histone deacetylase 6
  • Cytochrome P450 3A
  • Histone Deacetylase 4 (HDAC4) Mutant (H976Y)
  • Histone deacetylase
  • Histone deacetylase 1
  • Histone deacetylase 10
  • Histone deacetylase 11
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Potassium voltage-gated channel subfamily H member 2
9 Ki 42 IC50
  • (2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl}phenyl)prop-2-enamide
  • (E)-N-hydroxy-3-[4-[[2-hydroxyethyl-[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]prop-2-enamide
  • CHEMBL356066
  • Dacinostat
  • LAQ-824
  • NVP-LAQ824
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Collagenase 3
  • Interstitial collagenase
  • Matrix metalloproteinase 12
  • Matrix metalloproteinase 14
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • Metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Neutrophil collagenase
  • Stromelysin-1
22 IC50
  • US9206139, 2
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Collagenase 3
  • Interstitial collagenase
  • Matrix metalloproteinase 12
  • Matrix metalloproteinase 14
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • Metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • Neutrophil collagenase
  • Stromelysin-1
22 IC50
  • US9206139, 3
  • Bile acid receptor
  • Bile acid receptor FXR
  • Liver X Receptor alpha (LXR-alpha)
  • Liver X Receptor beta (LXR-beta)
  • Liver X receptor
  • Nuclear receptor ROR-alpha
  • Nuclear receptor ROR-beta
  • Nuclear receptor ROR-gamma (RORC)
  • Nuclear receptor subfamily 1 group I member 2
  • Oxysterols receptor LXR-alpha
  • Oxysterols receptor LXR-beta
  • Presenilin-1
  • alpha-Glucosidase (alpha-Glu)
  • lxralpha
  • lxrbeta
5 Ki 56 IC50 2 Kd 100 EC50
  • CHEMBL62136
  • N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide
  • T 0901317
  • T0901317
  • TO-901317
  • US10543183, Compound TO901317
  • US10669296, Compound TO901317
  • [3H]T0901317
  • Acyl-protein thioesterase 1
  • Acyl-protein thioesterase 1 (APT1 I75L)
  • Acyl-protein thioesterase 1 (APT1 I75L/S82A)
  • Acyl-protein thioesterase 1 (APT1 I75L/S82A/Q83P)
  • Acyl-protein thioesterase 1 (APT1 I75L/S82A/Q83P/R149H/A150R/S151A)
  • Acyl-protein thioesterase 1 (APT1 L176M)
  • Acyl-protein thioesterase 1 (APT1 Q83P)
  • Acyl-protein thioesterase 2
  • Acyl-protein thioesterase 2 (APT2 H152R)
  • Acyl-protein thioesterase 2 (APT2 L78I)
  • Acyl-protein thioesterase 2 (APT2 L78I/A85S)
  • Acyl-protein thioesterase 2 (APT2 L78I/A85S/P86Q)
  • Acyl-protein thioesterase 2 (APT2 L78I/A85S/P86Q/H152R/R153A/A154S)
  • Acyl-protein thioesterase 2 (APT2 M178L)
  • Acyl-protein thioesterase 2 (APT2 P86Q)
17 Ki
  • ML348
  • M3 muscarinic receptor (M3'(3C)-Xa A177C)
  • M3 muscarinic receptor (M3'(3C)-Xa F550C)
  • M3 muscarinic receptor (M3'(3C)-Xa F554C)
  • M3 muscarinic receptor (M3'(3C)-Xa K178C)
  • M3 muscarinic receptor (M3'(3C)-Xa K548C)
  • M3 muscarinic receptor (M3'(3C)-Xa K555C)
  • M3 muscarinic receptor (M3'(3C)-Xa R176C)
  • M3 muscarinic receptor (M3'(3C)-Xa R179C)
  • M3 muscarinic receptor (M3'(3C)-Xa R551C)
  • M3 muscarinic receptor (M3'(3C)-Xa T180C)
  • M3 muscarinic receptor (M3'(3C)-Xa T549C)
  • M3 muscarinic receptor (M3'(3C)-Xa T552C)
  • M3 muscarinic receptor (M3'(3C)-Xa T553C)
  • M3 muscarinic receptor (M3'(3C)-Xa T556C)
  • M3 muscarinic receptor (M3'(3C)-Xa)
22 Kd
  • N-methylscopolamine (NMS)
  • Egl nine homolog 1
  • Histone lysine demethylase MINA (MINA)
  • Histone lysine demethylase NO66 (NO66)
  • Histone lysine demethylase PHF8
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • Hypoxia-inducible factor 1 (FIH)
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 3B (KDM3B)
  • Lysine-specific demethylase 4A (KDM4A)
  • Lysine-specific demethylase 4C
  • Lysine-specific demethylase 5A
  • Lysine-specific demethylase 5B
  • Lysine-specific demethylase 5C
  • Lysine-specific demethylase 5D (KDM5D)
  • Lysine-specific demethylase 6B
24 IC50 1 Kd
  • KDOAM-25
  • 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3)
  • Aldo-keto reductase family 1 member C1
  • Aldo-keto reductase family 1 member C2
  • Aldo-keto reductase family 1 member C4 (AK1C4)
  • Aldo-keto-reductase family 1 member C3
  • Arachidonate 5-lipoxygenase
  • Bile salt export pump
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Cyclooxygenase-2 (COX-2)
  • Intestinal fatty acid-binding protein (hIFABP)
  • Liver fatty acid binding protein (rat L-FABP)
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Transcription factor SOX-18 (SOX-18)
  • Transthyretin
6 Ki 29 IC50 1 Kd
  • 2-[(2,6-dichloro-3-methylphenyl)amino]benzoic acid
  • CHEMBL509
  • Meclofenamate
  • Meclofenamic acid
  • 5-lipoxygenase/FLAP
  • Aryl Hydrocarbon Receptor (AhR)
  • Aryl hydrocarbon receptor
  • Bcr-Abl
  • Cyclooxygenase
  • Cytochrome P450 1A
  • Cytochrome P450 1A1
  • Cytochrome P450 1B1
  • Estrogen receptor
  • P-glycoprotein 1
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Protein kinase C alpha type
  • Ribosyldihydronicotinamide dehydrogenase [quinone]
  • Transient receptor potential cation channel subfamily A member 1
  • Transient receptor potential cation channel subfamily V member 1
3 Ki 12 IC50 2 EC50
  • 1,3-dimethoxy-5-[(E)-2-(4-methoxyphenyl)ethenyl]benzene
  • CHEMBL296411
  • trans-Stilbene Derivative, 4a
  • PTGER3
  • PTGER4
  • PTGIR
  • Prostaglandin D Synthase
  • Prostaglandin E2 receptor
  • Prostaglandin E2 receptor EP1 subtype (EP1)
  • Prostaglandin E2 receptor EP2 subtype
  • Prostaglandin E2 receptor EP4 subtype
  • Prostaglandin F2-alpha receptor
  • Prostaglandin Transporter
  • Prostanoid DP receptor
  • Prostanoid EP1 Receptor
  • Prostanoid EP2 Receptor
  • Prostanoid EP3 Receptor
  • Prostanoid IP receptor
20 Ki 7 IC50 3 EC50
  • 5-[(2E,3aS,4R,5R,6aS)-5-hydroxy-4-[(1E,3S)-3-hydroxy-4-methyloct-1-en-6-yn-1-yl]-octahydropentalen-2-ylidene]pentanoic acid
  • CHEMBL494
  • ILOPROST
  • Ventavis
  • [3H]-Iloprost
  • 1,3-beta-glucan synthase component GLS2
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • DNA-dependent protein kinase
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Serine-protein kinase ATM
  • Serine/threonine-protein kinase ATR
  • mTOR/FKBP12A/FKBP12B
21 IC50
  • US9428503, 1
  • Cereblon/Histone deacetylase 6
  • Cytochrome P450 3A
  • Histone Deacetylase 4 (HDAC4) Mutant (H976Y)
  • Histone deacetylase 1
  • Histone deacetylase 11
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 3/NCoR1
  • Histone deacetylase 3/Nuclear receptor corepressor 2 (HDAC3/NCoR2)
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Leukotriene A4 hydrolase
  • Potassium voltage-gated channel subfamily H member 2
53 IC50 3 Other
  • CHEMBL272980
  • MGCD-0103
  • MGCD0103
  • N-(2-aminophenyl)-4-({[4-(pyridin-3-yl)pyrimidin-2-yl]amino}methyl)benzamide
  • US10227295, Compound MGCD0103
  • US9409858, MGCD0103
  • US9751832, MGCD0103
  • US9956192, Compound MGCD0103
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Cytochrome P450 1A
  • Cytochrome P450 2A6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • FLT3(D835H)
  • FLT3(D835Y)
  • Potassium voltage-gated channel subfamily H member 2
  • Receptor-type tyrosine-protein kinase FLT3 (K663Q)
  • Receptor-type tyrosine-protein kinase FLT3 (R834Q)
  • Tyrosine Kinase FLT3 Mutant (N841I)
  • Tyrosine-protein kinase receptor FLT3
8 IC50 8 Kd
  • US9447092, 1
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
39 Ki
  • 2-(hydrazinecarbonyl)-3-phenyl-1H-indole-5-sulfonamide
  • BMC173212 Compound 1
  • CHEMBL262628
  • indole sulfonamide, L
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 2-(hydrazinecarbonyl)-3-(2-methylphenyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2a
  • indole sulfonamide, 8a
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 2-(hydrazinecarbonyl)-3-(3-methylphenyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2b
  • indole sulfonamide, 8b
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 2-(hydrazinecarbonyl)-3-(4-methylphenyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2c
  • indole sulfonamide, 8c
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 3-(2-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2d
  • indole sulfonamide, 8d
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 3-(3-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2e
  • indole sulfonamide, 8e
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 3-(4-fluorophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2f
  • indole sulfonamide, 8f
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 3-(2-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2g
  • indole sulfonamide, 8g
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 3-(3-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2h
  • indole sulfonamide, 8h
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 3-(4-chlorophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2i
  • indole sulfonamide, 8i
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 3-(2-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2j
  • indole sulfonamide, 8j
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 3-(3-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2k
  • indole sulfonamide, 8k
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 3-(4-bromophenyl)-2-(hydrazinecarbonyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2l
  • indole sulfonamide, 8l
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • alpha-Carbonic Anhydrase
  • beta-Carbonic Anhydrase
15 Ki
  • 2-(hydrazinecarbonyl)-3-(3-methoxyphenyl)-1H-indole-5-sulfonamide
  • BMC173212 Compound 2m
  • indole sulfonamide, 8m
  • Cereblon/Histone deacetylase 6
  • Free fatty acid receptor 3
  • Histone Lysine Demethylase
  • Histone deacetylase
  • Histone deacetylase 1
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Methyl-accepting chemotaxis protein (McpS)
  • Solute carrier family 22 member 20
  • Solute carrier family 22 member 6
3 Ki 10 IC50 1 Kd 1 EC50
1 ΔG°
  • Butyrate
  • butanoic acid
  • butanoic acid, 4
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Androgen receptor
  • Arachidonate 5-lipoxygenase
  • Butyrylcholinesterase (BChE)
  • Chemokine CXCL12
  • Cholinesterases
  • Cyclooxygenase-2 (COX-2)
  • Dihydrofolate reductase
  • Pancreatic alpha-amylase
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Thioredoxin reductase 1, cytoplasmic
  • Tumor necrosis factor receptor R1
  • perilipin-1
  • perilipin-5
1 Ki 16 IC50
  • CHEMBL7976
  • Chalcone 1
  • Chalcone, 13
  • cid_637760
  • substituted chalcone, 5j
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • ADRA2A
  • Adrenergic receptor alpha
  • Adrenergic receptor alpha-2
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Bile salt export pump
  • Serotonin (5-HT) receptor
  • Sphingosine 1-phosphate receptor 3
  • exonuclease V (RecBCD complex), alpha chain
13 Ki 4 IC50 5 EC50
  • 2-(4-tert-butyl-2,6-dimethyl-benzyl)-2-imidazoline;hydrochloride
  • 2-[(4-tert-butyl-2,6-dimethyl-phenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride
  • 2-[(4-tert-butyl-2,6-dimethylphenyl)methyl]-4,5-dihydro-1H-imidazole;hydrochloride
  • CHEMBL312448
  • MLS000069695
  • SMR000058526
  • XYLOMETAZOLINE HYDROCHLORIDE
  • Xylometazoline
  • cid_5282386
  • 5-hydroxytryptamine receptor 1A
  • Agp1p
  • Beta lactamase
  • DNA damage-inducible transcript 3 protein
  • DNA recombination protein RecA
  • Hsf1 protein
  • Nuclear receptor ROR-alpha
  • STAT3
  • Serotonin (5-HT) receptor
  • Sphingosine 1-phosphate receptor 3
  • Steroidogenic Factor 1
  • Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial
  • Toll-like receptor 9
  • Transcription Factor STAT1
  • XBP1
12 IC50 5 EC50
  • 2-(methylsulfonyl)-4-phenyl-6-(trifluoromethyl)pyrimidine
  • 2-mesyl-4-phenyl-6-(trifluoromethyl)pyrimidine
  • 2-methylsulfonyl-4-phenyl-6-(trifluoromethyl)pyrimidine
  • MLS000044644
  • SMR000022588
  • cid_3236803
  • Aurora kinase A/Targeting protein for Xklp2
  • CDK2/CycE
  • CDK7/Cyclin H/MNAT1
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 7 (CDK7)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 2
  • Ephrin type-A receptor 2 (EPHA2)
  • High affinity nerve growth factor receptor
  • Serine/threonine-protein kinase WEE1
  • Tyrosine- and threonine-specific cdc2-inhibitory kinase
  • Wee1-like protein kinase 2
21 IC50 4 Kd
  • Milciclib
  • pyrazolo[4,3-h]quinazoline-3-carboxamide, 28
  • Dual Specificity Protein Phosphatase 1
  • Dual specificity phosphatase Cdc25B
  • Estradiol receptor beta (ERβ)
  • Glyceraldehyde-3-phosphate dehydrogenase liver
  • Heat Shock 70kDa Protein 1
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • MKP-3
  • NS3
  • Voltage-gated calcium channel subunit alpha Cav2.2
  • core protein
  • eukaryotic translation initiation factor 4 gamma, 1 isoform 4
  • heat shock 70kDa protein 8 isoform 2
  • lens epithelium-derived growth factor p75
  • neuronal munc18-1 binding protein
28 IC50
  • 6-hydroxy-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
  • 6-oxidanyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
  • MLS-0015717.0001
  • cid_654089
  • Angiotensin II receptor
  • Apelin receptor
  • Apoptosis regulator Bcl-2
  • BCL-W
  • BZLF2
  • Bcl-2-like protein 11
  • Bcl-2-related protein A1
  • G protein signalling regulator 19
  • Glucose 6-phosphate dehydrogenase (G6PD)
  • RGS7
  • Regulator of G-protein signaling 8
  • glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
  • regulator of G-protein signaling 4
  • regulator of G-protein signalling 16
  • streptokinase A precursor
3 Ki 7 IC50 16 EC50
  • 3-[[7-(1,3-benzothiazol-2-ylsulfanyl)-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]propyl acetate
  • 3-[[7-(1,3-benzothiazol-2-ylsulfanyl)-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]propyl ethanoate
  • MLS000521052
  • SMR000131461
  • acetic acid 3-[[7-(1,3-benzothiazol-2-ylthio)-4-nitro-2,1,3-benzoxadiazol-5-yl]amino]propyl ester
  • acetic acid 3-[[7-(1,3-benzothiazol-2-ylthio)-4-nitro-benzofurazan-5-yl]amino]propyl ester
  • cid_11957209
  • Apoptotic peptidase activating factor 1
  • Bcl-2-related protein A1
  • Caspase-3
  • Caspase-9
  • Heat shock protein HSP 90-alpha
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • MSRA protein
  • Phospholipase A2
  • Phospholipase C, gamma 1
  • Phospholipase C-beta-3
  • SUMO-1-specific protease
  • SUMO/sentrin specific peptidase family member 8
  • cysteine protease ATG4B isoform a
  • putative hexokinase HKDC1
  • tyrosyl-DNA phosphodiesterase 2
17 IC50 1 EC50
  • 4-({(4Z)-1-oxo-4-[(phenylsulfonyl)imino]-1,4-dihydronaphthalen-2-yl}amino)benzoic acid
  • 4-[(4-besylimino-1-keto-2-naphthyl)amino]benzoic acid
  • 4-[[(4Z)-4-besylimino-1-keto-2-naphthyl]amino]benzoic acid
  • 4-[[1-oxidanylidene-4-(phenylsulfonylimino)naphthalen-2-yl]amino]benzoic acid
  • 4-[[4-(benzenesulfonylimino)-1-oxo-2-naphthalenyl]amino]benzoic acid
  • 4-[[4-(benzenesulfonylimino)-1-oxonaphthalen-2-yl]amino]benzoic acid
  • MLS000686314
  • SMR000313157
  • cid_4053104
  • Alkaline phosphatase placental-like
  • Alkaline phosphatase, tissue-nonspecific isozyme
  • Alpi
  • Bcl-2-like protein 1
  • Estradiol receptor beta (ERβ)
  • Gag-Pol polyprotein
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • Intestinal alkaline phosphatase
  • Sphingosine 1-phosphate receptor 3
  • TCRAV4S1
  • heat shock protein 90
  • large T antigen
  • leucine aminopeptidase
  • neutrophil cytosolic factor 1
  • serum albumin precursor
16 IC50 2 EC50
  • 1-(3,4-dihydroxyphenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone
  • 1-(3,4-dihydroxyphenyl)-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]thio]ethanone
  • 1-[3,4-bis(oxidanyl)phenyl]-2-[[4-ethyl-5-(2-methoxyphenyl)-1,2,4-triazol-3-yl]sulfanyl]ethanone
  • MLS000080517
  • SMR000038049
  • cid_665183
  • Aurora B/Incenp
  • Aurora kinase A/Targeting protein for Xklp2
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Dual specificity protein kinase TTK
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • MPI protein
  • Multidrug resistance-associated protein 4
  • Phosphodiesterase 1
  • Phosphodiesterase 3
  • Phosphodiesterase 4
  • Sigma non-opioid intracellular receptor 1
  • perilipin-1
  • perilipin-5
4 Ki 33 IC50
  • Amrinon
  • Amrinone
  • CHEMBL12856
  • Cordemcura
  • INAMRINONE
  • Inocor
  • MLS000069829
  • SMR000058850
  • Win40680
  • Wincoram
  • cid_3698
  • Coagulation factor X
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Nuclear receptor subfamily 1 group I member 2
  • Plasminogen
  • Potassium voltage-gated channel subfamily H member 2
  • Prothrombin
  • Tissue-type plasminogen activator
  • Urokinase-type plasminogen activator
  • Vitamin K-dependent protein C
6 Ki 15 IC50 1 EC50
  • CHEMBL551991
  • cyanoguanidine, 3
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
15 IC50
  • US10294227, Code 585
  • tert-butyl N-[4-[4-amino-1-[2-(4-methoxy-1-piperidyl)ethyl]pyrazolo[3,4-d]pyrimidin-3-yl]-2-methoxy-phenyl]carbamate (593)
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
15 IC50
  • US10294227, Code 503
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
15 IC50
  • US10294227, Code 584
  • Alkaline phosphatase placental-like
  • Alkaline phosphatase, tissue-nonspecific isozyme
  • Alpi
  • DNA dC->dU-editing enzyme APOBEC-3G
  • Eph receptor A4
  • Focal adhesion kinase 1
  • Intestinal alkaline phosphatase
  • Kallikrein 5
  • PTK2B protein tyrosine kinase 2 beta (PTK2B)
  • Phospholipase C, gamma 1
  • Phospholipase C-beta-3
  • cardiac alpha tropomyosin
  • lens epithelium-derived growth factor p75
  • probable DNA dC->dU-editing enzyme APOBEC-3A
  • protein artemis isoform a
18 IC50
  • 2-[(5Z)-5-[(E)-3-(2-furanyl)prop-2-enylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]propanoic acid
  • 2-[(5Z)-5-[(E)-3-(2-furyl)prop-2-enylidene]-4-keto-2-thioxo-thiazolidin-3-yl]propionic acid
  • 2-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid
  • 2-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]propanoic acid
  • 2-{5-[(E)-3-Furan-2-yl-prop-2-en-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-propionic acid
  • MLS000551724
  • SMR000145649
  • cid_6375556
  • Alpha trans-inducing protein (VP16)
  • Apoptotic peptidase activating factor 1
  • Caspase-9
  • DNA recombination protein RecA
  • Dual specificity protein phosphatase (VHR)
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Lipoamide Dehydrogenase (Lpd)
  • Nuclear receptor coactivator 1
  • Phospholipase A2
  • Pyruvate dehydrogenase (PDH)
  • Tyrosine-protein kinase ABL1
  • cell division cycle 42 (GTP binding protein, 25kDa)
  • cysteine protease ATG4B isoform a
  • nuclear receptor coactivator 3 isoform a
17 IC50 1 EC50
  • 1-ethyl-6-methyl-3-[(E)-2-phenylethenyl]pyrimido[5,4-e][1,2,4]triazine-5,7-dione
  • 1-ethyl-6-methyl-3-[(E)-styryl]pyrimido[5,4-e][1,2,4]triazine-5,7-quinone
  • MLS000717146
  • SMR000278513
  • US9073941, 609
  • cid_5756371
  • Cytoplasmic tyrosine-protein kinase BMX
  • EGF-R Tyrosine Kinase
  • EGF-R Tyrosine Kinase Mutant (T790M)
  • Epidermal growth factor receptor
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase 11
  • Src Mutant (S345C)
  • Src Mutant (S345C/T338M)
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK3
40 IC50
  • 4-anilinoquinazoline deriv. 2
  • BMC163482 Compound 1
  • CHEMBL285063
  • N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}prop-2-enamide
  • US9422297, PD168393
  • Hemagglutinin-neuraminidase
  • Neuraminidase
  • Neuraminidase A
  • Neuraminidase A (NanA)
  • Neuraminidase B
  • Neuraminidase B (NanB)
  • Neuraminidase C (NanC)
  • Sialidase
  • Sialidase 1
  • Sialidase 2
  • Sialidase 3
  • Sialidase 4
  • Sialidase A
  • Sialidase B
  • Trans-sialidase
19 Ki 66 IC50
  • (2R,3R,4S)-3-acetamido-4-hydroxy-2-[(1R,2R)-1,2,3-trihydroxypropyl]-3,4-dihydro-2H-pyran-6-carboxylic acid
  • 2,3-didehydro-2-deoxy-N-acetylneuraminic acid
  • CHEMBL96712
  • DANA
  • Neu5Ac2en
  • Dual specificity mitogen-activated protein kinase kinase 5
  • FLT3-ITD
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Fyn (Y531F)
  • Tyrosine-protein kinase Fyn Isoform B
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
  • flt3
17 IC50 1 Kd
  • (3S,4R)-3-((4-amino-3-(4-phenoxyphenyl)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-1,2-dithiolan-4-ol
  • US10844038, Example 43 A.
  • Apoptotic peptidase activating factor 1
  • Beta-galactosidase
  • C-C chemokine receptor type 6 (CCR6)
  • Caspase-3
  • Caspase-9
  • Heat shock protein HSP 90-alpha
  • MSRA protein
  • POsterior Segregation family member (pos-1)
  • PPP5C protein
  • RecName: Full=Zinc finger protein mex-5
  • SUMO-1-specific protease
  • SUMO/sentrin specific peptidase family member 8
  • protein phosphatase 1, catalytic subunit, alpha isoform 3
  • putative hexokinase HKDC1
  • tyrosyl-DNA phosphodiesterase 2
15 IC50 3 EC50
  • 3-[[(4E)-4-(2,4-dimethylphenyl)sulfonylimino-1-keto-2-naphthyl]amino]benzoic acid
  • 3-[[(4E)-4-(2,4-dimethylphenyl)sulfonylimino-1-oxidanylidene-naphthalen-2-yl]amino]benzoic acid
  • 3-[[(4E)-4-(2,4-dimethylphenyl)sulfonylimino-1-oxo-2-naphthalenyl]amino]benzoic acid
  • 3-[[(4E)-4-(2,4-dimethylphenyl)sulfonylimino-1-oxonaphthalen-2-yl]amino]benzoic acid
  • MLS000948061
  • SMR000620247
  • cid_5824726
  • D(2) dopamine receptor
  • DRD1
  • Delta-type opioid receptor
  • Glutamate receptor ionotropic, NMDA 1
  • HTR3A
  • Imidazoline I1
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • OPRD1
  • Opioid receptor
  • Sigma intracellular receptor 2
  • Sigma non-opioid intracellular receptor 1
  • Sigma-1 receptor
  • Vesicular acetylcholine transporter
  • Zinc finger protein 664
44 Ki 7 IC50 2 EC50
  • (+)-PENTAZOCINE
  • (-)-pentazocine
  • (2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
  • (6R,11S)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
  • 6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
  • 6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol(Pentazocine)
  • CHEMBL560
  • PENTAZOCINE (+)
  • PENTAZOCINE (-)
  • Pentazocine
  • Pentazocine,(+/-)
  • Talacen
  • Talwin
  • US10231963, Table B.8
  • US10736890, Compound TABLE B.8
  • US9656961, Example 00125
  • rel-(2R,6R,11R)-6,11-Dimethyl-3-(3-methyl-but-2-enyl)-1,2,3,4,5,6-hexahydro-2,6-methano-benzo[d]azocin-8-ol
  • ADRA2A
  • Adrenergic receptor alpha
  • Adrenergic receptor alpha-2
  • Alpha adrenergic receptor (1a and 1d)
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Bile salt export pump
  • G-protein subunit alpha-16
  • Imidazoline I1
  • Imidazoline receptor 1 (I1R)
  • Serotonin (5-HT) receptor
  • trace amine-associated receptor 1
17 Ki 6 IC50 10 EC50
  • 2-Naphthalen-1-ylmethyl-4,5-dihydro-1H-imidazole; hydrochloride
  • Albalon
  • CHEMBL1706
  • NAPHAZOLINE
  • NAPHAZOLINE HYDROCHLORIDE
  • Nafazair
  • Naphazoline
  • Naphazoline Nitrate
  • Naphcon forte
  • Opcon
  • Vasocon
  • cid_11079
  • Cytochrome P450 1A
  • G protein-activated inward rectifier potassium channel 1
  • Galanin receptor 2
  • Glucocorticoid receptor
  • Mast/stem cell growth factor receptor Kit
  • Nuclear receptor ROR-alpha
  • Reverse transcriptase
  • Rho-associated protein kinase 2
  • Steroidogenic Factor 1
  • Topoisomerase II alpha (HuTopoIIα)
  • Tyrosine-protein kinase Lck
  • Voltage-dependent T-type calcium channel subunit alpha-1H
  • cAMP-dependent protein kinase (PKA)
  • diphosphomevalonate decarboxylase
  • streptokinase A precursor
13 IC50 5 EC50
  • 5,11-dimethyl-2H-pyrido[4,3-b]carbazole
  • CHEMBL123
  • ELLIPTECINE
  • Ellipticin
  • Ellipticine
  • TCMDC-125546
  • cid_3213
  • Beta tubulin
  • DNA topoisomerase 1
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • P-glycoprotein 1
  • Phosphodiesterase 4
  • Proto-oncogene tyrosine-protein kinase Src
  • Similar to alpha-tubulin isoform 1
  • Tubulin
  • Tubulin alpha chain /beta chain
  • Tubulin beta chain
  • Tubulin beta-1 chain
  • Tubulin beta-3 chain
  • Tyrosine-protein kinase ABL1
2 Ki 94 IC50 1 Kd
  • (-)-combretastatin
  • (Z)-3'-hydroxy-3,4,4',5-tetramethoxystilbene
  • (Z)-5-(3,4,5-trimethoxystyryl)-2-methoxyphenol
  • (combretastatin A-4)2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol
  • (combretastin A-4)2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol
  • 2-Methoxy-5-[(Z)-2-(3,4,5-trimethox y-phenyl)-vinyl]-phenol
  • 2-Methoxy-5-[(Z)-2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol
  • 2-Methoxy-5-[2-(3,4,5-trimethoxy-phenyl)-vinyl]-phenol
  • 2-methoxy-5-(3,4,5-trimethoxystyryl)phenol
  • 2-methoxy-5-[(Z)-2-(3,4,5-trimethoxyphenyl)vinyl]phenol
  • 5-(3,4,5-trimethoxystyryl)-2-methoxyphenol
  • 5-[(S)-2-Hydroxy-2-(3,4,5-trimethoxy-phenyl)-ethyl]-2-methoxy-phenol
  • CHEMBL67
  • Combrestatin A-4
  • Combrestatin A4
  • Combretastastin A-4
  • Combretastatin
  • Combretastatin-A4
  • Combretastin A-4
  • Z-Combretastatin A-4
  • combretastatin A-4, (CSA4)
  • combretastin A4
  • 5-hydroxytryptamine receptor 3A
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • Adrenergic receptor alpha-1
  • Adrenergic receptor alpha-2
  • Adrenergic receptor beta
  • Alpha-1A adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • HTR4
  • Serotonin (5-HT) receptor
  • Serotonin 1 (5-HT1) receptor
  • Serotonin 2 (5-HT2) receptor
  • Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
25 Ki 7 IC50 5 EC50
  • (exo)4-Amino-5-chloro-N-(hexahydro-pyrrolizin-1-ylmethyl)-2-methoxy-benzamide
  • 4-Amino-5-chloro-2-methoxy-N-(7a-methyl-hexahydro-pyrrolizin-1-ylmethyl)-benzamide
  • 4-Amino-5-chloro-N-(hexahydro-pyrrolizin-2-ylmethyl)-2-methoxy-benzamide
  • 4-Amino-5-chloro-N-[(1S,7aS)-1-(hexahydro-pyrrolizin-1-yl)methyl]-2-methoxy-benzamide
  • 4-amino-5-chloro-N-[(1S-cis-hexahydro-1H-pyrrolizin-1-yl)-methyl]-2-methoxybenzenecarboxamide
  • CHEMBL34291
  • SC-53116
  • SC49518
  • SC53116
  • 5-hydroxytryptamine receptor 1A (5HT1A)
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 3A
  • Adenosine receptor A2b
  • Alpha-2A adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(2) dopamine receptor
  • Dopamine D1 receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M3
  • Serotonin 2a (5-HT2a) receptor
  • Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
15 Ki
  • 2-(5-Methyl-1H-imidazol-4-ylmethyl)-4-phenyl-thiazole
  • CHEMBL38465
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 3A
  • D(2) dopamine receptor
  • Histamine H1 receptor
  • Histamine H2 Receptor
  • Neuronal acetylcholine receptor Alpha-4/Beta-2
  • Neuronal acetylcholine receptor protein alpha-4/beta-4 subunit
  • Nicotinic acetylcholine receptor alpha2/beta2
  • Nicotinic acetylcholine receptor alpha2/beta4
  • Norepinephrine Monoamine transporters
  • Serotonin 2 (5-HT2) receptor
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
12 Ki 4 EC50
  • 1-(1H-Indol-3-yl)-2-propanamine
  • 1-(1H-indol-3-yl)propan-2-amine
  • 3-(2-Aminopropyl)indole
  • CHEMBL30713
  • DL-3-(2-Aminopropyl)indole
  • Indopan
  • alpha-Methyl-1H-indole-3-ethanamine
  • alpha-Methyl-3-indoleethanamine
  • alpha-Methyl-beta-indoleethylamine
  • alpha-methyltryptamine
  • Acidic alpha-glucosidase
  • Alpha-glucosidase MAL62
  • Alpha-mannosidase 2C1
  • Beta-mannosidase
  • Glucoamylase, intracellular sporulation-specific
  • Glycogen Phosphorylase (PYGL)
  • Glycogen debranching enzyme
  • Glycogen phosphorylase, muscle form
  • Lactase-glycosylceramidase
  • Liver glycogen phosphorylase
  • Maltase-glucoamylase
  • Mannosidase 2 alpha 1
  • Mannosidase 2, alpha B1
  • Trehalase
  • alpha-Glucosidase (α-Glucosidase)
3 Ki 22 IC50
  • 2-Hydroxymethyl-pyrrolidine-3,4-diol
  • BDBM50031485
  • CHEMBL305131
  • CHEMBL80254
  • Imino-D-Arabinitol
  • Cereblon/Histone deacetylase 6
  • Cytochrome P450 1A
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Histone deacetylase 1
  • Histone deacetylase 11
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Potassium voltage-gated channel subfamily H member 2
1 Ki 15 IC50
  • CHEMBL3286732
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2B
  • ADRA2C
  • Adrenergic receptor alpha-2
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(2) dopamine receptor
  • HTR1A
  • Nuclear receptor subfamily 1 group I member 2
  • Serotonin 1B/1D receptor
  • Serotonin 2 (5-HT2) receptor
  • Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
  • adrenergic Alpha2
51 Ki 3 EC50
  • 8-(2,3-Dihydro-benzo[1,4]dioxin-2-ylmethyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one
  • CHEMBL300555
  • Spiroxatrine
  • PTGDR
  • PTGER3
  • PTGFR
  • PTGIR
  • Prostaglandin D Synthase
  • Prostaglandin E2 receptor
  • Prostaglandin E2 receptor EP1 subtype (EP1)
  • Prostaglandin E2 receptor EP2 subtype
  • Prostaglandin E2 receptor EP4 subtype
  • Prostaglandin F2-alpha receptor
  • Prostaglandin Transporter
  • Prostanoid EP1 Receptor
  • Prostanoid EP3 Receptor
  • Prostanoid IP receptor
  • TBXA2R
20 Ki
  • (S-isomer)7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid
  • (Z)-7-[(1R,3R,5S)-3,5-Dihydroxy-2-((E)-(S)-3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid
  • 7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid
  • CHEMBL12114
  • PGF2Alpha
  • Prostaglandin F2alpha7-[3,5-Dihydroxy-2-(3-hydroxy-oct-1-enyl)-cyclopentyl]-hept-5-enoic acid
  • CDC2-like kinase 3 (CLK3)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent-like kinase 5
  • Dual specificity protein kinase CLK1
  • Dual specificity protein kinase CLK2
  • Dual specificity protein kinase CLK4
  • Dual specificty protein kinase CLK1
  • Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
  • Dual-specificity tyrosine-phosphorylation regulated kinase 1A
  • Dual-specificity tyrosine-phosphorylation regulated kinase 2
  • Dual-specificity tyrosine-phosphorylation regulated kinase 3
  • Dual-specificity tyrosine-regulated kinases 1B
15 IC50
  • CHEMBL3297832
  • 5-hydroxytryptamine receptor 1A
  • Adrenergic alpha1B
  • Adrenergic receptor
  • Adrenergic receptor alpha
  • Adrenergic receptor alpha-2
  • Alpha adrenergic receptor (1a and 1d)
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Imidazoline I1
  • Imidazoline receptor 1 (I1R)
  • Nischarin
12 Ki 2 IC50 16 EC50
  • 2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole
  • 2-(2-Cyclopropyl-phenoxymethyl)-4,5-dihydro-1H-imidazole (cirazoline)
  • CHEMBL13852
  • CIRAZOLINE
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2C
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • D(2) dopamine receptor
  • Histamine H1 receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Norepinephrine transporter
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
26 Ki
  • 4-(3,4-Dichloro-phenyl)-1,2,3,4-tetrahydro-naphthalen-1-ylamine, HCl
  • CHEMBL40733
  • Desmethylsertraline
  • Adrenaline alpha1
  • Adrenaline alpha2
  • Adrenergic receptor
  • Adrenergic receptor alpha
  • Adrenergic receptor alpha-2
  • Adrenergic receptor beta
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Beta-3 adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Mu-type opioid receptor
18 Ki 3 IC50 3 Kd 14 EC50
  • (-)-(R)-epinephrine
  • (-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol
  • (-)-adrenaline
  • (R)-(-)-adrenaline
  • (R)-adrenaline
  • 4-[(1R)-1-hydroxy-2-(methylamino)ethyl]benzene-1,2-diol
  • Adrenalin
  • CHEMBL679
  • EPINEPHRINE
  • adrenaline
  • levoepinephrine
  • Bile salt export pump
  • Calcium channel (Type L)
  • Dihydrofolate reductase
  • Potassium voltage-gated channel subfamily H member 2
  • Sigma non-opioid intracellular receptor 1
  • Sodium channel protein type 10 subunit alpha
  • Sodium channel protein type 2 alpha subunit
  • Sodium channel protein type 5 subunit alpha
  • Sodium channel protein type 9 subunit alpha
  • Sodium channel protein type I I alpha subunit
  • Sodium channel protein type II alpha subunit
  • Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
  • Voltage-gated sodium channel subunit alpha Nav1.3 (Nav1.3)
  • Voltage-gated sodium channel subunit alpha Nav1.4 (Nav1.4)
  • Voltage-gated sodium channel subunit alpha Nav1.8
2 Ki 26 IC50
  • 6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamine
  • 6-(2,3-Dichloro-phenyl)-[1,2,4]triazine-3,5-diamine(lamotrigine)
  • 6-(2,3-dichlorophenyl)-1,2,4-triazine-3,5-diamine
  • BW-430C
  • CHEMBL741
  • LAMOTRIGINE
  • Lamictal
  • Lamictal cd
  • 5-hydroxytryptamine receptor 1A
  • Acetylcholinesterase
  • Adrenergic receptor alpha-2
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Calcium channel
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Serotonin 1B/1D receptor
  • Serotonin 2 (5-HT2) receptor
  • Sodium-dependent noradrenaline transporter
24 IC50
  • CHEMBL29835
  • Indol-1-yl-propyl-pyridin-4-yl-amine
  • Indol-1-yl-propyl-pyridin-4-yl-amine(Besipirdine)
  • GABA A Alpha4Beta2Gamma2
  • GABA A receptor alpha-2/beta-2/gamma-2
  • GABA A receptor alpha-3/beta-2/gamma-2
  • GABA A receptor alpha-5/beta-3/gamma-2
  • GABA A receptor alpha-6/beta-2/gamma-2
  • GABA receptor alpha-1/beta-3/gamma-2 subunit
  • GABA receptor alpha-2/beta-2/gamma-2 subunit
  • GABA receptor alpha-2/beta-3/gamma-2 subunit
  • GABA receptor alpha-3/beta-2/gamma-2 subunit
  • GABA receptor alpha-3/beta-3/gamma-2 subunit
  • GABA receptor alpha-5/beta-3/gamma-2 subunit
  • GABA receptor alpha-6/beta-3/gamma-2 subunit
  • GABA-A receptor; alpha-1/beta-2/gamma-2
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A))
23 Ki 3 IC50 5 EC50
  • 8-Ethynyl-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-triaza-benzo[e]azulene-3-carboxylic acid tert-butyl ester
  • 8-Ethynyl-5-methyl-6-oxo-5,6-dihydro-4H-2,5,10b-triaza-benzo[e]azulene-3-carboxylic acid tert-butyl ester(RY 24)
  • CHEMBL58757
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • HTR2C
  • Sigma non-opioid intracellular receptor 1
44 Ki 2 IC50 2 EC50
  • 1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperidin-4-ol
  • 3-[4-(4-chlorophenyl)-4-hydroxypiperidinyl]methylindole
  • 4-(4-Chloro-phenyl)-1-(1H-indol-3-ylmethyl)-piperidin-4-ol
  • CHEMBL445102
  • L-741626
  • L741,626
  • DNA (cytosine-5)-methyltransferase 1 (DNMT1)
  • Histone-lysine N-methyltransferase EHMT1
  • Histone-lysine N-methyltransferase SETDB1
  • Histone-lysine N-methyltransferase SUV39H2 (Suv39H2)
  • Histone-lysine N-methyltransferase, H3 lysine-79 specific
  • Myeloid/lymphoid or mixed-lineage leukemia (MLL)
  • Protein G9a (G9a)
  • Protein arginine N-methyltransferase 5
  • Protein arginine methyltransferase 3 (PRMT3)
  • Protein lysine methyltransferase SUV4-20H1 (SUV4-20H1)
  • Protein lysine methyltransferase SUV4-20H2 (SUV4-20H2)
  • Protein-arginine N-methyltransferase 1
  • SET and MYND domain-containing protein 2 (SMYD2)
  • SET domain-containing protein 7/9 (Set7/9)
  • SET domain-containing protein 8 (SetD8)
17 IC50 2 Kd
  • CHEMBL3318285
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Dopamine receptor
  • Histamine H1 receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma intracellular receptor 2
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
17 Ki
  • CHEMBL3321788
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Dopamine receptor
  • Histamine H1 receptor
  • Sigma intracellular receptor 2
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
17 Ki
  • CHEMBL3321789
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Dopamine receptor
  • Histamine H1 receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma intracellular receptor 2
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
17 Ki
  • CHEMBL3321790
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 7
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Dopamine receptor
  • Histamine H1 receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma intracellular receptor 2
  • Sigma non-opioid intracellular receptor 1
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
17 Ki
  • CHEMBL3321792
  • Cannabinoid receptor
  • Cannabinoid receptor 1
  • Cannabinoid receptor 2
  • Cytochrome P450 1A
  • Cytochrome P450 1B1
  • Fatty-acid amide hydrolase 1
  • N-acylethanolamine-hydrolyzing acid amidase
  • Peroxisome proliferator-activated receptor
  • Sigma non-opioid intracellular receptor 1
  • Sn1-specific diacylglycerol lipase alpha
  • Transient receptor potential M8 protein (TRPM8)
  • Transient receptor potential cation channel subfamily A member 1
  • Transient receptor potential cation channel subfamily V member 1
  • Transient receptor potential cation channel, subfamily V, member 3
  • Vanilloid receptor
14 Ki 4 IC50 11 EC50
  • 6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol
  • 6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol (Cannabinol)
  • 6,6,9-Trimethyl-3-pentyl-6H-benzo[c]chromen-1-ol(Cannabinol)
  • CANNABINOL
  • CHEMBL74415
  • Adrenaline alpha1
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 3A
  • Cytochrome P450 3A5 (CYP3A5)
  • HIV-1 protease
  • Human immunodeficiency virus type 1 protease
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Multidrug resistance-associated protein 4
  • Potassium voltage-gated channel subfamily H member 2
  • Protease
  • Sodium channel protein type 5 subunit alpha
  • Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
  • Voltage-gated potassium channel subunit Kv4.3
10 Ki 21 IC50 3 Kd
  • (3S,4aS,8aS)-2-[(2R,3R)-2-Hydroxy-3-(3-hydroxy-2-methyl-benzoylamino)-4-phenylsulfanyl-butyl]-decahydro-isoquinoline-3-carboxylic acid tert-butylamide; compound with methanesulfonic acid
  • AG-1343
  • CHEMBL1205
  • NELFINAVIR MESYLATE
  • Nelfinavir
  • Viracept
  • Cathepsin D
  • Coagulation factor X
  • Complement C1r
  • Complement C1r subcomponent
  • Complement C1s
  • Hepatocyte growth factor activator
  • Hepsin
  • Integrin alpha-2/beta-3
  • Integrin alpha-IIb/beta-3
  • Kallikrein-1 (KLK1)
  • Matriptase
  • Plasminogen
  • Prothrombin
  • Trypsin
  • Trypsin-1
7 Ki 25 IC50 1 EC50
  • 4-Guanidino-benzoic acid 6-carbamimidoyl-naphthalen-2-yl ester
  • 4-Guanidino-benzoic acid 6-carbamimidoyl-naphthalen-2-yl ester(FUT-175)
  • CHEMBL273264
  • Nafamostat
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Beta-secretase 1
  • Beta-secretase 2
  • Cathepsin D
  • Cathepsin E
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Mu-type opioid receptor
  • Pepsinogen A5
  • Pepsinogen C
  • Potassium voltage-gated channel subfamily H member 2
  • Renin
17 IC50
  • CHEMBL3403995
  • Bile salt export pump
  • C-C motif chemokine 3
  • C-C motif chemokine 4
  • Cereblon isoform 4
  • DNA damage-binding protein 1
  • Glyceraldehyde-3-phosphate dehydrogenase cytosolic
  • Granulocyte-macrophage colony-stimulating factor
  • Interleukin-6
  • Mediator of DNA damage checkpoint protein 1
  • Phosphodiesterase 4
  • Prostaglandin G/H synthase (Cyclooxygenase-2)
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Protein cereblon
  • Tumor necrosis factor
  • hIL-1beta
3 Ki 15 IC50
  • (+/-)-thalidomide
  • 2-(2,6-Dioxo-piperidin-3-yl)-isoindole-1,3-dione
  • 2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione
  • CHEMBL468
  • K-17
  • THALIDOMIDE
  • Thalomid
  • [(R,S)-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Alpha-1A adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Histamine H1 receptor
  • Muscarinic acetylcholine receptor M1
  • Potassium voltage-gated channel subfamily H member 2
  • Sodium-dependent serotonin transporter
15 Ki 1 IC50 2 EC50
  • CHEMBL3409256
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 3A
  • Alpha-2A adrenergic receptor
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • HTR6
  • Histamine H1 receptor
  • Serotonin (5-HT) receptor
  • Serotonin 1b (5-HT1b) receptor
  • Serotonin 4 (5-HT4) receptor
17 Ki
  • (7-Chloro-2,3-dihydro-benzo[1,4]dioxin-2-ylmethyl)-[1-(2-methoxy-phenyl)-piperidin-4-ylmethyl]-amine
  • CHEMBL418854
  • Cytochrome P450 1A
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • GRM7
  • GRM8
  • Glutamate receptor ionotropic, NMDA 2B
  • Luciferin 4-monooxygenase
  • Metabotropic glutamate receptor
  • Metabotropic glutamate receptor 1
  • Metabotropic glutamate receptor 2
  • Metabotropic glutamate receptor 3
  • Metabotropic glutamate receptor 4 (mGluR4)
  • Metabotropic glutamate receptor 5
  • Metabotropic glutamate receptor 6
  • Monoamine oxidase
42 Ki 42 IC50 1 Kd
  • 2-Methyl-6-(phenylethynyl)pyridine
  • 2-Methyl-6-phenylethynyl-pyridine
  • 2-Methyl-6-phenylethynyl-pyridine(MPEP)
  • 2-methyl-6-(2-phenylethynyl)pyridine
  • 2-methyl-6-(phenyl-ethynyl)pyridine
  • 2-methyl-6-(phenylethynyl)-pyridine
  • 6-methyl-2-(2-phenylethynyl)pyridine
  • CHEMBL1788108
  • CHEMBL66654
  • MPEP
  • US10618900, No. MPEP
  • [3H]-2-methyl-6-(phenylethynyl)-pyridine
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cruzipain
  • Intestinal fatty acid-binding protein (hIFABP)
  • Liver fatty acid binding protein (human L-FABP T94A)
  • Liver fatty acid binding protein (human L-FABP T94T)
  • Liver fatty acid binding protein (rat L-FABP)
  • Multidrug resistance-associated protein 4
  • Organic anion-transporting polypeptide 1D1 (Oatp1d1)
  • Peroxisome proliferator-activated receptor
  • Peroxisome proliferator-activated receptor alpha
  • Peroxisome proliferator-activated receptor alpha (PPAR alpha)
  • Peroxisome proliferator-activated receptor gamma
7 Ki 10 IC50 16 Kd 22 EC50
1 ΔG°
  • 2-(4-(4-Chlorobenzoyl)phenoxy)-2-methylpropanoic acid 1-methylethyl ester
  • CHEMBL672
  • FENOFIBRATE
  • FNF
  • Fenofibric acid
  • Finofibrate
  • Isopropyl (4'-(p-chlorobenzoyl)-2-phenoxy-2-methyl)propionate
  • Isopropyl 2-(4-(4-chlorobenzoyl)phenoxy)-2-methylpropionate
  • Lipantil (TN)
  • Procetofen
  • Tricor (TN)
  • propan-2-yl 2-[4-(4-chlorobenzoyl)phenoxy]-2-methylpropanoate
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Arachidonate 15-lipoxygenase
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 2
  • Indoleamine 2,3-dioxygenase 1
  • Indoleamine 2,3-dioxygenase 2
  • Monoamine Oxidase Type B (MAO-B)
  • Monoamine oxidase
  • Multidrug resistance-associated protein 4
  • Peroxisome proliferator-activated receptor
  • Peroxisome proliferator-activated receptor gamma
  • Protein-tyrosine phosphatase 1B
  • Uridine-5'-diphosphoglucuronosyltransferase 1A6
8 Ki 18 IC50 17 EC50
  • 5-((4-((6-hydroxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-chromen-2-yl)methoxy)phenyl)methyl)thiazolidine-2,4-dione
  • 5-(4-((6-hydroxy-2,5,7,8-tetramethylchroman-2-yl)methoxy)benzyl)thiazolidine-2,4-dione
  • 5-[4-(6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-ylmethoxy)-benzy l]-thiazolidine-2,4-dione (troglitazone)
  • 5-[4-(6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-ylmethoxy)-benzyl]-thiazolidine-2,4-dione
  • 5-[4-(6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-ylmethoxy)-benzyl]-thiazolidine-2,4-dione(troglitazone)
  • 5-[4-(6-Hydroxy-2,5,7,8-tetramethyl-chroman-2-ylmethoxy)-benzyl]-thiazolidine-2,4-dioneTroglitazone
  • CHEMBL408
  • CI-991
  • CS-045
  • GR92132X
  • PRELAY
  • REZULIN
  • TROGLITAZONE
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • Alpha-1A adrenergic receptor
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • HTR6
  • Histamine H1 receptor
  • KCNQ (Kv7) potassium channel
  • Potassium voltage-gated channel subfamily H member 2
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
35 Ki 2 IC50
  • (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol
  • (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol (M 100907)
  • (2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol(MDL 100907)
  • (R)-(1-(4-fluorophenethyl)piperidin-4-yl)(2,3-dimethoxyphenyl)methanol
  • (R)-(2,3-Dimethoxy-phenyl)-{1-[2-(4-fluoro-phenyl)-ethyl]-piperidin-4-yl}-methanol
  • (R)-(2,3-Dimethoxyphenyl)-(1-(2-p-fluorophenylethyl)-piperidine-4-yl)-methanol
  • (R)-(2,3-dimethoxyphenyl)(1-(4-fluorophenethyl)piperidin-4-yl)methanol
  • CHEMBL74355
  • MDL 100907
  • MDL-100907
  • ATP-binding cassette sub-family G member 2
  • Canalicular multispecific organic anion transporter 2
  • Cruzipain
  • Gag-Pol polyprotein (Capsid Protein)
  • HIV-1 Reverse transcriptase (HIV-1 RT)
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Multidrug resistance-associated protein 2 (MRP2)
  • P-glycoprotein 1
  • Potassium voltage-gated channel subfamily H member 2
  • Reverse Transcriptase
  • Reverse transcriptase
  • Reverse transcriptase (HIV-1 RT)(1-350)
  • Sodium channel protein type 5 subunit alpha
  • Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
  • Voltage-gated potassium channel subunit Kv4.3
92 IC50 9 EC50
1 ΔG°
  • 4-(6-amino-5-bromo-2-(4-cyanophenylamino)pyrimidin-4-ylamino)-3,5-dimethylbenzonitrile
  • 4-(6-amino-5-bromo-2-(4-cyanophenylamino)pyrimidin-4-yloxy)-3,5-dimethylbenzonitrile
  • 4-({6-AMINO-5-BROMO-2-[(4-CYANOPHENYL)AMINO]PYRIMIDIN-4-YL}OXY)-3,5-DIMETHYLBENZONITRILE
  • 4-[6-amino-5-bromo-2-(4-cyano-phenylamino)-pyrimidin-4-yloxy]-3,5-dimethyl-benzonitrile
  • CHEMBL308954
  • ETRAVIRINE
  • Etravirine (ETR)
  • Etravirine (ETV)
  • Etravirine (TMC125)
  • TMC 125
  • TMC-125
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • Adenosine receptor A1
  • Adenosine receptor A3
  • Adrenergic receptor alpha-1
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Melatonin receptor
  • Mu-type opioid receptor
  • Neurokinin 2 receptor
  • Sodium-dependent noradrenaline transporter
  • Translocator protein
  • Vasopressin V1a receptor
18 IC50
  • 4-(2-Oxo-2,3-dihydro-benzoimidazol-1-yl)-piperidine-1-carboxylic acid 6-chloro-benzo[1,3]dioxol-5-ylmethyl ester
  • CHEMBL115444
  • CDK7/Cyclin H/MNAT1
  • CDK8/Cyclin C
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 7 (CDK7)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 12
  • Cyclin-dependent kinase 13
  • Cyclin-dependent kinase 13/Cyclin-K
  • Cyclin-dependent kinase 7
  • Interleukin-1 receptor-associated kinase 1
  • Mitogen-activated protein kinase 8
  • Mitogen-activated protein kinase 9
  • Mitogen-activated protein kinase kinase kinase 11
1 Ki 31 IC50 1 EC50
  • CHEMBL3603847
  • US10787436, Compound I-23
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDK2/CycE
  • CDK2/Cyclin A/Cyclin A1
  • CDK3/E
  • CDK6/CycD3
  • CDK7/Cyclin H/MNAT1
  • Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-Y
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 9
7 Ki 17 IC50
  • AT-7519
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cyclooxygenase
  • Cytochrome P450 1A
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • DNA Gyrase
  • Monoamine Oxidase Type B (MAO-B)
  • Multidrug resistance-associated protein 4
  • Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial
  • Voltage-gated L-type calcium channel
  • streptokinase A precursor
4 Ki 21 IC50 1 EC50
  • (Linezolid)N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide
  • (R)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
  • (S)-3-(3-Fluoro-4-morpholin-4-yl-phenyl)-5-[(1-hydroxy-ethylamino)-methyl]-oxazolidin-2-one
  • (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-oxooxazolidin-5-yl)methyl)acetamide
  • (S)-N-((3-fluoro-4-morpholinophenyl)-2-oxaoxazolidin-5-yl)methyl)acetamide
  • Benzotriazol-2-yl-acetonitrile
  • CHEMBL126
  • LINEZOLID
  • Linezoid
  • N-((S)-2-oxo-3-(S)-2,3,3a,4-tetrahydro-1H-benzo[b]pyrrolo[1,2-d][1,4]oxazin-7-yl-oxazolidin-5-ylmethyl)-acetamide
  • N-[(R)-3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide
  • N-[(S)-3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide
  • N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide
  • N-[3-(3-Fluoro-4-morpholin-4-yl-phenyl)-2-oxo-oxazolidin-5-ylmethyl]-acetamide(linezolid)
  • N-{[(5S)-3-(3-fluoro-4-morpholin-4-ylphenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide
  • U-100766
  • Zyvox
  • cid_441401
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Dopamine D1 receptor
  • Histamine H1 receptor
  • Serotonin (5-HT) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
15 Ki 1 EC50
  • (2,4-Dimethyl-azetidin-1-yl)-(7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-9-yl)-methanone
  • CHEMBL138989
  • GRIA1
  • GRIA2
  • GRIA3
  • GRIK1
  • Glutamate receptor 1
  • Glutamate receptor ionotropic AMPA
  • Glutamate receptor ionotropic, AMPA
  • Glutamate receptor ionotropic, AMPA 2
  • Glutamate receptor ionotropic, AMPA 4
  • Glutamate receptor ionotropic, kainate
  • Glutamate receptor ionotropic, kainate 1
  • Glutamate receptor ionotropic, kainate 2
  • Ionotropic glutamate receptor kainate 2/5
  • Metabotropic glutamate receptor 1
  • NMDA receptor subunit 2C (GluN2C)
15 Ki 2 IC50 14 EC50
  • (R,S)-2-amino-3-(4-chloro-3-hydroxy-5-isoxazolyl)propionate
  • 2-Amino-3-(4-chloro-3-hydroxy-isoxazol-5-yl)-propionic acid
  • CHEMBL72366
  • 3',5'-cyclic phosphodiesterase
  • 5-hydroxytryptamine receptor 1A
  • Acetylcholinesterase
  • Butyrylcholinesterase (BuChE)
  • Cholinesterase
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Cytochrome P450 1A
  • Cytochrome P450 1A1
  • Cytochrome P450 1B1
  • Cytochrome P450 3A
  • Matrix metalloproteinase-9
  • Oxysterols receptor LXR-beta
  • Protein DAF-12, isoform a
  • Vanilloid receptor
2 Ki 16 IC50 1 EC50
  • 8,13-Dihydro-7H-indolo[2',3':3,4]pyrido[2,1-b]quinazolin-5-one
  • CHEMBL85139
  • cid_65752
  • rutaecarpine
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 7
  • Adrenergic receptor alpha-1
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Histamine H1 receptor
  • Norepinephrine Monoamine transporters
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
29 Ki
  • (3R,3aS)-7,8-Dimethoxy-3-[4-((E)-2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole
  • (3R,3aS)-7,8-Dimethoxy-3-[4-(2-methyl-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole
  • CHEMBL91157
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 7
  • Adrenergic receptor alpha-1
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Histamine H1 receptor
  • Norepinephrine Monoamine transporters
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
29 Ki
  • (3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole
  • (3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-but-2-enyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole
  • CHEMBL419316
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 7
  • Adrenergic receptor alpha-1
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Histamine H1 receptor
  • Norepinephrine Monoamine transporters
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
26 Ki
  • (3R,3aS)-7,8-Dimethoxy-3-(4-naphthalen-2-ylmethyl-piperazin-1-ylmethyl)-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole
  • CHEMBL92860
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 7
  • Adrenergic receptor alpha-1
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Histamine H1 receptor
  • Norepinephrine Monoamine transporters
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
29 Ki
  • (3R,3aS)-7,8-Dimethoxy-3-[4-((E)-3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole
  • (3R,3aS)-7,8-Dimethoxy-3-[4-(3-phenyl-allyl)-piperazin-1-ylmethyl]-3a,4-dihydro-3H-chromeno[4,3-c]isoxazole
  • CHEMBL328114
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Alpha-2A adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Histamine H1 receptor
  • Serotonin (5-HT) receptor
  • Sigma intracellular receptor 2
16 Ki 1 IC50
  • 2-[4-(3,4-Dimethyl-phenyl)-piperazin-1-ylmethyl]-1H-benzoimidazole
  • CHEMBL127257
  • CDC2-like kinase 3 (CLK3)
  • Dual specificity protein kinase CLK4
  • Dual specificty protein kinase CLK1
  • Dual-specificity tyrosine-phosphorylation regulated kinase 1A
  • Dual-specificity tyrosine-phosphorylation regulated kinase 2
  • Dual-specificity tyrosine-regulated kinases 1B
  • Epidermal growth factor receptor
  • PKC alpha and beta-2
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Serine/threonine-protein kinase 17A
  • Serine/threonine-protein kinase haspin
  • Serine/threonine-protein kinase pim-1
  • myosin light chain kinase 2
16 IC50
  • CHEMBL3774448
  • Acetylcholinesterase
  • Aldose reductase (AR)
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Arachidonate 15-lipoxygenase
  • Arachidonate 5-lipoxygenase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 2
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Cyclooxygenase
  • Glyceraldehyde-3-phosphate dehydrogenase liver
  • Sorbitol dehydrogenase
6 Ki 11 IC50
  • 6-Methoxy-7-hydroxycoumarin
  • 6-Methylesculetin
  • 6-O-Methylesculetin
  • 7-Hydroxy-6-methoxy-2H-1-benzopyran-2-one
  • 7-hydroxy-6-methoxy-2H-chromen-2-one
  • CHEMBL71851
  • scopoletin
  • Calpain-1
  • Carboxylesterase
  • Cathepsin A (CTSA)
  • Cathepsin B
  • Cathepsin S
  • Cruzipain
  • Cysteine protease falcipain-3
  • Dipeptidyl peptidase I
  • Falcipain 2
  • Falcipain-2
  • Leukocyte elastase
  • Papain
  • Pro-cathepsin H
  • Procathepsin L
  • Rhodesain
7 Ki 26 IC50
  • CHEMBL374508
  • E-64
  • E64
  • Bacteriophage T4 DNA Ligase
  • CAM-RNase A
  • DNA topoisomerase
  • DNA topoisomerase 1
  • DNA topoisomerase I
  • DNA topoisomerase I (Topo I)
  • Deoxyribonuclease-1
  • Deoxyribonuclease-2-alpha
  • Telomerase reverse transcriptase
  • Topoisomerase II alpha (HuTopoIIα)
  • Type-2 restriction enzyme BamHI
  • Type-2 restriction enzyme EcoRI
  • Type-2 restriction enzyme HindIII
  • Type-2 restriction enzyme PstI
  • Type-2 restriction enzyme ScaI
21 IC50
  • 6-Hydroxy-3-[1-(4-hydroxy-phenyl)-meth-(E)-ylidene]-3H-benzofuran-2-one
  • CHEMBL195416
  • isoaurostatin
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Lethal(3)malignant brain tumor-like protein 1 (L3MBTL1)
  • Lethal(3)malignant brain tumor-like protein 3 (L3MBTL3)
  • Lethal(3)malignant brain tumor-like protein 4
  • MBT domain-containing protein 1 (MBTD1)
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Muscarinic acetylcholine receptor M4
  • Muscarinic acetylcholine receptor M5
  • Voltage-dependent L-type calcium channel subunit alpha-1C
15 Ki 11 IC50
  • 4-(Diethylamino)-2-butynyl alpha-phenylcyclohexaneglycolic acid ester
  • 4-(diethylamino)but-2-yn-1-yl cyclohexyl(hydroxy)phenylacetate
  • 4-Diethylamino-2-butinyl alpha-cyclohexylmandelat
  • 4-Diethylamino-2-butynyl alpha-phenylcyclohexaneglycolate
  • Benzeneacetic acid, alpha-cyclohexyl-alpha-hydroxy-, 4-(diethylamino)-2-butynyl ester
  • CHEMBL1231
  • Cyclohexaneglycolic acid, alpha-phenyl-, 4-(diethylamino)-2-butynyl ester
  • OXYBUTYNIN CHLORIDE
  • ALK tyrosine kinase receptor
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Hepatocyte growth factor receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 3
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase ABL1
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
15 IC50
  • CHEMBL3798631
  • ALK tyrosine kinase receptor
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Hepatocyte growth factor receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 3
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase ABL1
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
15 IC50
  • CHEMBL3798257
  • CDK2/Cyclin A/Cyclin A1
  • CDK6/CycD3
  • Casein kinase I
  • Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
  • Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3/cAMP-dependent protein kinase alpha-catalytic subunit
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 7 (CDK7)
  • Cyclin-dependent kinase 1
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 2
  • Mitogen-activated protein kinase 1
  • PDGFR-beta/Platelet-derived growth factor receptor alpha
  • Serine/threonine-protein kinase AKT2
  • Vascular endothelial growth factor receptor 2
15 IC50
  • 3-{4-[4-(3-Chloro-phenylamino)-[1,3,5]triazin-2-yl]-pyridin-2-ylamino}-propan-1-ol
  • CHEMBL191336
  • Adrenaline alpha1
  • Adrenaline alpha2
  • Adrenergic Alpha
  • Androgen receptor
  • Anti-estrogen binding site (AEBS)
  • C-8 sterol isomerase
  • Corticosteroid-binding globulin
  • Mineralocorticoid receptor
  • Organic anion-transporting polypeptide 1D1 (Oatp1d1)
  • Sigma non-opioid intracellular receptor 1
  • Solute carrier family 22 member 1
  • Solute carrier family 22 member 2
  • Solute carrier family 22 member 3
  • Solute carrier organic anion transporter family member 1A1
  • Testis-specific androgen-binding protein
14 Ki 10 IC50 2 Kd
  • (11beta)-11,21-dihydroxypregn-4-ene-3,20-dione
  • 11beta,21-dihydroxypregn-4-ene-3,20-dione
  • 11beta,21-dihydroxyprogesterone
  • 17-deoxycortisol
  • CHEMBL110739
  • corticosterone
  • DNA damage-inducible transcript 3 protein
  • DNA repair protein RAD51 homolog 1
  • Delta-type opioid receptor
  • FXN frataxin
  • Glucocorticoid receptor
  • Hsf1 protein
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • Mast/stem cell growth factor receptor Kit
  • Melanocortin receptor 4
  • Mitogen-activated protein kinase kinase kinase kinase 2
  • Probable global transcription activator SNF2L2
  • Reverse transcriptase
  • XBP1
  • neutrophil cytosolic factor 1
  • streptokinase A precursor
11 IC50 8 EC50
  • 9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole
  • 9-Methoxy-5,11-dimethyl-6H-pyrido[4,3-b]carbazole9-OCH3-E
  • 9-methoxy ellipticine
  • 9-methoxyellipticine
  • CHEMBL19954
  • O-methylellipticine
  • cid_72512
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Cyclin-dependent kinase 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor
  • Focal adhesion kinase 1
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase 8
  • Potassium voltage-gated channel subfamily H member 2
  • Proto-oncogene tyrosine-protein kinase Src
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase JAK3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
18 IC50
  • CHEMBL201307
  • N-(3-fluorophenyl)-2-(2-(7-(3-(4-(hydroxymethyl)piperidin-1-yl)propoxy)-6-methoxyquinazolin-4-ylamino)thiazol-5-yl)acetamide
  • N-(3-fluorophenyl)-2-{2-[(7-{3-[4-(hydroxymethyl)piperidin-1-yl]propoxy}-6-methoxyquinazolin-4-yl)amino]-1,3-thiazol-5-yl}acetamide
  • N-3-fluorophenyl)-2-2-7-3-4-hydroxymethyl)piperidin-1-yl)propoxy)-6-methoxyquinazolin-4-ylamino)thiazol-5-yl)acetamide
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • ADAM17
  • ADAMTS1
  • Collagenase 3
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Interstitial collagenase
  • Matrix metalloproteinase 15
  • Matrix metalloproteinase 16
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Stromelysin-1
13 Ki 2 IC50
  • CHEMBL208009
  • N-(4-(2-(hydroxyamino)-2-oxoethyl)piperidin-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide
  • 72 kDa type IV collagenase
  • A disintegrin and metalloproteinase with thrombospondin motifs 4 (ADAMTS-4)
  • A disintegrin and metalloproteinase with thrombospondin motifs 5 (ADAMTS-5)
  • ADAM17
  • ADAMTS1
  • Collagenase 3
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Interstitial collagenase
  • Matrix metalloproteinase 15
  • Matrix metalloproteinase 16
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Stromelysin-1
28 Ki 1 IC50
  • CHEMBL207305
  • N-(4-(2-(hydroxyamino)-2-oxoethyl)-tetrahydro-2H-pyran-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide
  • N-(4-(2-(hydroxyamino)-2-oxoethyl)tetrahydro-2H-pyran-4-yl)-4-((2-methylquinolin-4-yl)methoxy)benzamide
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
1 Ki 27 IC50
  • CHEMBL3824089
  • US10294227, Code 506
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
21 IC50
  • CHEMBL3824233
  • US10294227, Code 518
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
21 IC50
  • CHEMBL3823104
  • US10294227, Code 519
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
17 IC50
  • CHEMBL3823711
  • US10294227, Code 540
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
17 IC50
  • CHEMBL3823255
  • US10294227, Code 526
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
21 IC50
  • CHEMBL3823543
  • US10294227, Code 533
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
17 IC50
  • CHEMBL3824228
  • US10294227, Code 543
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
17 IC50
  • CHEMBL3824021
  • US10294227, Code 556
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
21 IC50
  • CHEMBL3823620
  • US10294227, Code 553
  • Mast/stem cell growth factor receptor Kit
  • Peptidyl-prolyl cis-trans isomerase FKBP1B/Serine/threonine-protein kinase mTOR
  • Platelet-derived growth factor receptor alpha
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
17 IC50
  • CHEMBL3824116
  • US10294227, Code 565
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Ephrin type-B receptor 4
  • Fibroblast growth factor receptor 2
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase Yes
  • Vascular endothelial growth factor receptor 2
18 Ki 13 IC50
  • ([7-(2,6-dichloro-phenyl)-5-methyl-benzo[1,2,4]triazin-3-yl]-[4-(2-pyrrolidin-1-yl-ethoxy)-phenyl]-amine)
  • 7-(2,6-dichlorophenyl)-5-methyl-N-(4-(2-(pyrrolidin-1-yl)ethoxy)phenyl)benzo[e][1,2,4]triazin-3-amine
  • 7-(2,6-dichlorophenyl)-5-methyl-N-[4-(2-pyrrolidin-1-ylethoxy)-phenyl]-1,2,4-benzotriazin-3-amine
  • CHEMBL230686
  • TG-100435
  • US8481536, 367
  • US8481536, 575
  • 3',5'-cyclic phosphodiesterase
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Phosphodiesterase 11A (PDE11A)
  • Phosphodiesterase 3 and 5 (PDE3 and PDE5)
  • Phosphodiesterase 6C (PDE6C)
  • Phosphodiesterase 7
  • Phosphodiesterase 8
  • Phosphodiesterase 9A
  • cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform 1
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • cGMP-specific 3',5'-cyclic phosphodiesterase
15 IC50
  • CHEMBL3884788
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