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Compounds Sorted by Binding Targets per Compound

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56   57   58   59   60   61   62   63   64   65   66   67   68   69   70   73   74   75   76   77   79   81   84   86   89   95   
96   100   108   109   120   124   130   137   143   154   156   168   186   224   240   259   276   278   284   303   
304   310   315   323   339   369   370   371   372   373   374   375   376   377   378   380   381   383   384   
385   386   388   389   390   391   392   393   394   395   397   398   401   403   404   406   408   418   427   
429   443   447   515   
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonate dehydratase
  • Carbonic Anhydrase (hpCA)
  • Carbonic Anhydrase IV
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIV
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
57 Ki 1 IC50
  • 6-hydroxy-1,3-benzothiazole-2-sulfonamide
  • CHEMBL6685
  • aromatic/heteroaromatic sulfonamide 19
  • Alpha carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonate dehydratase
  • Carbonic Anhydrase (hpCA)
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
44 Ki 2 IC50
  • 2-Hydrazinobenzenesulfonamide
  • 2-hydrazinylbenzene-1-sulfonamide
  • CHEMBL176495
  • aromatic/heteroaromatic sulfonamide 24
  • hydrazide deriv. 18
  • Adenosine A1 receptor
  • Adenosine A2 receptor
  • Adenosine A2a receptor
  • Adenosine Receptors A2a (A2a)
  • Adenosine receptor
  • Adenosine receptor A1
  • Adenosine receptor A2a
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Phosphodiesterase (TcrPDEC)
  • Phosphodiesterase 1
  • Phosphodiesterase 9A
  • Phosphodiesterase Type 3 (PDE3B)
  • Phosphodiesterase Type 5 (PDE5A)
  • Phosphodiesterase Type 5 (PDE5A) Mutant (del 661-681)
  • Phosphodiesterase Type 5 (PDE5A) Mutant (del 663-678)
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cGMP-specific 3',5'-cyclic phosphodiesterase
26 Ki 13 IC50 1 Kd
  • 1-methyl-3-(2-methylpropyl)-2,3,6,7-tetrahydro-1H-purine-2,6-dione
  • 1-methyl-3-(2-methylpropyl)-3,7-dihydro-1H-purine-2,6-dione
  • 3-Isobutyl-1-methylxanthine
  • CHEMBL275084
  • IBMX
  • isobutylmethylxanthine
  • 3-phosphoinositide dependent protein kinase-1
  • 6His.FMS.538-922(FGFR)
  • ALK tyrosine kinase receptor
  • Epidermal growth factor receptor
  • Insulin-like growth factor I receptor
  • Macrophage colony-stimulating factor 1 receptor (aa 538-972)
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase 17B (STK17B)
  • Serine/threonine-protein kinase SRPK1
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • cFMS -Tie-2 Chimera
15 IC50 2 Kd
  • (3Z)-3-(1H-pyrrol-2-ylmethylidene)-2,3-dihydro-1H-indol-2-one
  • CHEMBL86755
  • Indolinone based inhibitor, 1
  • Oxindole I
  • Homo sapiens lysine demethylase 2A (KDM2A)
  • Lysine-specific demethylase 3A
  • Lysine-specific demethylase 4A (KDM4A)
  • Lysine-specific demethylase 4C
  • Lysine-specific demethylase 5A
  • Lysine-specific demethylase 5A (KDM5A(aa 1-1090)-Flag)
  • Lysine-specific demethylase 5A (KDM5A(aa 1-588)ΔAP)
  • Lysine-specific demethylase 5A (KDM5A(aa 1-739)ΔAP(2C-2S))
  • Lysine-specific demethylase 5B
  • Lysine-specific demethylase 5B (KDM5B(aa 1-604)ΔAP)
  • Lysine-specific demethylase 5B (KDM5B(aa 1-755)ΔAP)
  • Lysine-specific demethylase 5C
  • Lysine-specific demethylase 5C (KDM5C(aa 1-789)ΔAP)
  • Lysine-specific demethylase 5D (KDM5D(aa 1-760)ΔAP)
  • Lysine-specific demethylase 5D (KDM5D)
  • Lysine-specific demethylase 6A
  • Lysine-specific demethylase 6B
23 IC50 2 Kd
  • KDOAM-21
  • ethyl 2-(((2-((2-(dimethylamino)ethyl)(ethyl)amino)-2-oxoethyl)amino)methyl)isonicotinate (KDM5-C70)
  • Acyl-protein thioesterase 1
  • Acyl-protein thioesterase 1 (APT1 I75L)
  • Acyl-protein thioesterase 1 (APT1 I75L/S82A)
  • Acyl-protein thioesterase 1 (APT1 I75L/S82A/Q83P)
  • Acyl-protein thioesterase 1 (APT1 I75L/S82A/Q83P/R149H/A150R/S151A)
  • Acyl-protein thioesterase 1 (APT1 L176M)
  • Acyl-protein thioesterase 1 (APT1 Q83P)
  • Acyl-protein thioesterase 2
  • Acyl-protein thioesterase 2 (APT2 H152R)
  • Acyl-protein thioesterase 2 (APT2 L78I)
  • Acyl-protein thioesterase 2 (APT2 L78I/A85S)
  • Acyl-protein thioesterase 2 (APT2 L78I/A85S/P86Q)
  • Acyl-protein thioesterase 2 (APT2 L78I/A85S/P86Q/H152R/R153A/A154S)
  • Acyl-protein thioesterase 2 (APT2 M178L)
  • Acyl-protein thioesterase 2 (APT2 P86Q)
  • Acyl-protein thioesterase 2 (APT2 S122A)
  • Pyridoxal kinase
18 Ki 4 IC50 2 Kd
  • ML349
  • Acetylcholinesterase
  • Acyl-CoA: cholesterol acyltransferase (ACAT)
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Carbon monoxide dehydrogenase (CODH)
  • Carboxylesterase 1
  • Caspase-1
  • Cholinesterases
  • DNA dC->dU-editing enzyme APOBEC-3G
  • Dihydroorotate dehydrogenase
  • Dihydroorotate dehydrogenase (quinone), mitochondrial
  • Dual specificity phosphatase Cdc25B
  • Dual specificity protein phosphatase 1
  • Factor XIIa
  • Indoleamine 2,3-dioxygenase
  • MDM2-MDMX
  • MKP-3
7 Ki 10 IC50 1 Kd 1 Other
  • 1,4-Benzoquinone
  • Benzil-related compound, 53
  • CHEMBL8320
  • benzoquinone
  • cid_4650
  • cyclohexa-2,5-diene-1,4-dione
  • α-glucosidase
  • α-Amylase group 4 allergen (Aca s 4)
  • Alpha glucosidase
  • Alpha-glucosidase
  • Alpha-glucosidase MAL12
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Multidrug resistance-associated protein 4
  • Pancreatic alpha-amylase
  • Probable maltase-glucoamylase 2
  • Sucrase-isomaltase
  • alpha-Amylase
  • alpha-Glucosidase (α-Glucosidase)
  • alpha-Glucosidase (α-glucosidase)
  • alpha-Glucosidase (alpha-Glu)
  • alpha-glucosidase (Gaa)
40 IC50
  • (3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5S,6R)-3,4-dihydroxy-6-methyl-5-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}oxan-2-yl]oxy}-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-6-(hydroxymethyl)oxane-2,3,4-triol
  • Acarbose
  • 3C-like proteinase (3CL-PRO)
  • Acetylcholinesterase
  • Alpha-glucosidase MAL62
  • Axin-1/Glycogen synthase kinase-3 beta
  • Butyrylcholinesterase (BChE)
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 7
  • Cytochrome P450 1A
  • Cytochrome P450 1A1
  • Cytochrome P450 1B1
  • Dipeptidyl peptidase 4
  • Lysine-specific histone demethylase 1A
  • Mitogen-activated protein kinase 14
  • alpha-Amylase
5 Ki 12 IC50 1 Kd 1 Other
  • (2S)-5,7-dihydroxy-2-(3-hydroxy-4-methoxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one
  • Hesperetin
  • Hesperitin
  • ADORA1
  • ADORA3
  • Adenosine A1 receptor
  • Adenosine A2 receptor
  • Adenosine A2a receptor
  • Adenosine Receptors A2a (A2a)
  • Adenosine receptor
  • Adenosine receptor A1
  • Adenosine receptor A1 (A1)
  • Adenosine receptor A2a
  • Adenosine receptor A2a and A3
  • Adenosine receptor A2b
  • Adenosine receptor A3
  • Equilibrative Nucleoside Transporter 1 (ENT1)
  • Genome polyprotein
  • Glyceraldehyde-3-phosphate dehydrogenase liver
  • Phosphoglycerate kinase 1
146 Ki 15 IC50 12 EC50
  • (2R,3R,4S,5R)-2-[6-(cyclopentylamino)-9H-purin-9-yl]-5-(hydroxymethyl)oxolane-3,4-diol
  • CHEMBL68738
  • CPA
  • N6-CyclopentylAdo
  • N6-cyclopentyladenosine (CPA)
  • cid_657378
  • Acetylcholinesterase
  • Amine oxidase (flavin-containing) A
  • Amine oxidase [flavin-containing] B
  • Apoptosis regulator Bcl-2
  • Aromatic-L-amino-acid decarboxylase
  • BCL-W
  • Bcl-2-like protein 1
  • Butyrylcholinesterase (BuChE)
  • Cell division control protein 42 homolog
  • Cholinesterases
  • Peroxisome proliferator-activated receptor
  • Protein kinase C alpha
  • Protein kinase C, epsilon
  • Ras-related C3 botulinum toxin substrate 1/T-lymphoma invasion and metastasis-inducing protein 1
  • Reverse transcriptase
  • Sarcoplasmic/endoplasmic reticulum calcium ATP-ase
  • Sarcoplasmic/endoplasmic reticulum calcium ATPase 1
8 Ki 15 IC50
  • 17,18-dimethoxy-21-methyl-5,7-dioxa-21-azapentacyclo[11.8.0.0^{2,10}.0^{4,8}.0^{14,19}]henicosa-1(13),2,4(8),9,11,14(19),15,17,20-nonaen-21-ium
  • CHEMBL13045
  • CHEMBL258893
  • Chelerytherine
  • Toddalin
  • chelerythrine
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Multidrug resistance-associated protein 4
12 Ki 6 IC50
  • 1,1-dioxo-6-(trifluoromethyl)-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide
  • BMCL182567 Compound 6b
  • Diuredemina
  • Glomerulin
  • Hydroflumethiazide
  • cid_3647
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 2
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Multidrug resistance-associated protein 4
  • Solute carrier family 22 member 6
  • electroneutral potassium-chloride cotransporter KCC2
13 Ki 5 IC50 2 EC50
  • 3-(butylamino)-4-phenoxy-5-sulfamoylbenzoic acid
  • Bumetanide
  • Bumex
  • Burinex
  • Fordiuran
  • cid_2471
  • Cytoplasmic tyrosine-protein kinase BMX
  • Ephrin receptor
  • Ephrin type-A receptor 1 (EPHA1)
  • Ephrin type-A receptor 2
  • Ephrin type-A receptor 3 (EPHA3)
  • Ephrin type-B receptor 2
  • Ephrin type-B receptor 3 (EPHB3)
  • Lck
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase Yes
  • Tyrosine-protein kinase receptor TYRO3
  • Uncharacterized aarF domain-containing protein kinase 4
1 IC50 18 Kd
  • 2,4-dianilino pyrimidine, 2
  • 3-({4-[(5-hydroxy-2-methylphenyl)amino]pyrimidin-2-yl}amino)benzamide
  • CHEMBL249097
  • Acetylcholinesterase
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 15
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Procollagen-proline,2-oxoglutarate-4-dioxygenase
  • Tyrosinase
22 Ki 15 IC50
1 ΔG°
  • 1,4-Dihydroxybenzene, XIII
  • 1,4-dihydroxybenzene
  • CHEMBL537
  • Hydroquinone (9)
  • Hydroquinone, HQ
  • benzene-1,4-diol
  • phenol derivative, 4
  • GABA A Alpha2Beta1Gamma2
  • GABA A Alpha4Beta2Gamma2
  • GABA A receptor alpha-3/beta-2/gamma-2
  • GABA A receptor alpha-6/beta-2/gamma-2
  • GABA receptor alpha-1/beta-3/gamma-2 subunit
  • GABA receptor alpha-2/beta-2/gamma-2 subunit
  • GABA receptor alpha-2/beta-3/gamma-2 subunit
  • GABA receptor alpha-3/beta-2/gamma-2 subunit
  • GABA receptor alpha-3/beta-3/gamma-2 subunit
  • GABA receptor alpha-5/beta-3/gamma-2 subunit
  • GABA receptor alpha-6/beta-3/gamma-2 subunit
  • GABA-A receptor; alpha-1/beta-2/gamma-2
  • GABAA Receptor, alpha-4, beta-2, gamma-2
  • GABAA Receptor, alpha-6, beta-2, gamma-2
  • Gamma-aminobutyric acid receptor (GABA(A)) subunit alpha-4
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Gamma-aminobutyric acid receptor subunit alpha-5 (GABA(A))
35 Ki 1 EC50
  • RO-154513
  • Ro15-4513
  • [3H]Ro15-4513
  • ethyl 12-azido-8-methyl-9-oxo-2,4,8-triazatricyclo[8.4.0.0^{2,6}]tetradeca-1(10),3,5,11,13-pentaene-5-carboxylate
  • 1,3-beta-glucan synthase component GLS2
  • Cytoplasmic tyrosine-protein kinase BMX
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor protein-tyrosine kinase erbB-4
  • SRC
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase Yes
19 IC50
  • 4-{8-amino-3-[(2R)-4-oxetan-3-ylmorpholin-2-yl]imidazo[1,5-a]pyrazin-1-yl}-N-[4-(trifluoromethyl)pyridin-2-yl]benzamide
  • US9718828, Example, 551
  • 1,3-beta-glucan synthase component GLS2
  • Cytoplasmic tyrosine-protein kinase BMX
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor protein-tyrosine kinase erbB-4
  • SRC
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase Yes
19 IC50
  • 4-(8-amino-3-{(3R)-1-[(3-methyloxetan-3-yl)carbonyl]azepan-3-yl}imidazo[1,5-a]pyrazin-1-yl)-N-[4-(trifluoromethyl)pyridin-2-yl]benzamide
  • US9718828, Example, 575
  • α-Carbonic anhydrase (αCA)
  • β-Carbonic anhydrase (βCA)
  • Alpha carbonic anhydrase
  • Alpha-carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Gamma-carbonic anhydrase
55 Ki
  • BDBM50098540
  • CHEMBL1362
  • CHEMBL1528
  • CHEMBL1644027
  • F-
  • fluoride
  • fluoride ion
  • α-Carbonic anhydrase (αCA)
  • β-Carbonic anhydrase (βCA)
  • Alpha carbonic anhydrase
  • Alpha-carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Gamma-carbonic anhydrase
80 Ki
  • CHEMBL363707
  • HCO3-
  • SODIUM BICARBONATE
  • bicarbonate ion
  • hydrogen carbonate
  • α-Carbonic anhydrase (αCA)
  • β-Carbonic anhydrase (βCA)
  • Alpha carbonic anhydrase
  • Alpha-carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Carbonic anhydrase, alpha family
  • Gamma-carbonic anhydrase
60 Ki
  • CHEMBL1644699
  • CHEMBL38703
  • HS anion
  • HS(-1)
  • hydrogen(sulfide)(-1)
  • hydrosulfide
  • sulfanide
  • α-Carbonic anhydrase (αCA)
  • β-Carbonic anhydrase (βCA)
  • Alpha carbonic anhydrase
  • Alpha-carbonic anhydrase
  • Astrosclerin-3
  • Beta-carbonic anhydrase
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XV
  • Carbonic anhydrase
  • Carbonic anhydrase 1
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Gamma-carbonic anhydrase
56 Ki
  • CHEMBL183495
  • SO4(2-)
  • SODIUM SULFATE
  • sulfate
  • sulfate ion
  • 5-hydroxytryptamine receptor 3A
  • Alpha-1A adrenergic receptor
  • Beta-secretase 1
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(4) dopamine receptor
  • G-protein subunit alpha-16
  • Norepinephrine transporter
  • Opioid receptor
  • Phenylethanolamine N-methyltransferase
  • Serotonin receptor 2a and 2b (5HT2A and 5HT2B)
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
  • TRAR1
  • Trace amine-associated receptor 1 (TAAR1)
  • TyR1
  • trace amine-associated receptor 1
11 Ki 2 IC50 2 Kd 7 EC50
  • CHEMBL11608
  • cid_5610
  • p-Tyramine
  • tyramine
  • 1,3-beta-glucan synthase component GLS2
  • 5-hydroxytryptamine receptor 1A
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Dihydrofolate reductase
  • Multidrug resistance-associated protein 4
  • Pteridine reductase 1
  • Sodium channel protein type 2 alpha subunit
  • Sodium channel protein type II alpha subunit
  • Twik-RElated Potassium (K+) channel 1 (TREK1)
  • Uridine-5'-diphosphoglucuronosyltransferase 1A1
1 Ki 18 IC50 2 EC50
  • CHEMBL744
  • MLS000069369
  • RILUZOLE
  • SMR000058231
  • cid_5070
  • DNA dC->dU-editing enzyme APOBEC-3G
  • Dual Specificity Protein Phosphatase 1
  • Dual specificity phosphatase Cdc25B
  • Gag-Pol polyprotein
  • Glyceraldehyde-3-phosphate dehydrogenase liver
  • Heat Shock 70kDa Protein 1
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • MKP-3
  • POsterior Segregation family member (pos-1)
  • RecName: Full=Zinc finger protein mex-5
  • eukaryotic translation initiation factor 4 gamma, 1 isoform 4
  • heat shock 70kDa protein 8 isoform 2
  • large T antigen
  • nuclear receptor subfamily 4, group A, member 1
  • probable DNA dC->dU-editing enzyme APOBEC-3A
30 IC50 2 EC50
  • 6,7-dimethyl-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-4-carboxylic acid
  • MLS-0007635.0001
  • cid_646406
  • 10 kDa chaperonin
  • 60 kDa chaperonin
  • Adrenergic Alpha
  • Estradiol receptor beta (ERβ)
  • Estrogen receptor
  • HSP60/HSP10
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • Multidrug and toxin extrusion protein 1
  • Multidrug and toxin extrusion protein 2
  • Nuclear receptor subfamily 1 group I member 2
  • Papain-like protease (PLpro)
  • Solute carrier family 22 member 2
  • Solute carrier family 22 member 3
  • Sphingosine 1-phosphate receptor 1
  • Thiosulfate sulfurtransferase
  • Zinc aminopeptidase
  • large T antigen
18 IC50 5 EC50
  • 2,2'-THIOBIS(4,6-DICHLOROPHENOL)
  • 2,4-dichloro-6-(3,5-dichloro-2-hydroxyphenyl)sulfanylphenol
  • 2,4-dichloro-6-[(3,5-dichloro-2-hydroxy-phenyl)thio]phenol
  • 2,4-dichloro-6-[(3,5-dichloro-2-hydroxyphenyl)thio]phenol
  • 2-[3,5-bis(chloranyl)-2-oxidanyl-phenyl]sulfanyl-4,6-bis(chloranyl)phenol
  • Bithionol
  • HL-3
  • MLS000028403
  • SMR000058374
  • cid_2406
  • B-RAF V600E
  • Cytoplasmic tyrosine-protein kinase BMX
  • Discoidin domain-containing receptor 2
  • Ephrin receptor
  • Epithelial discoidin domain-containing receptor 1
  • Platelet-derived growth factor receptor
  • Proto-oncogene tyrosine-protein kinase Src (T341M)
  • Proto-oncogene tyrosine-protein kinase Src (aa 1-530)
  • RAF proto-oncogene serine/threonine-protein kinase
  • Receptor tyrosine-protein kinase erbB-2
  • Serine/threonine-protein kinase B-raf
  • TAK1/TAB1
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Yes
  • Vascular endothelial growth factor receptor 2
19 IC50
  • US10266537, Compound 31
  • Angiopoietin-1 receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Dual specificty protein kinase CLK1
  • Dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Fructose-1,6-bisphosphatase
  • Fructose-1,6-bisphosphatase 1 (FBPase)
  • Insulin receptor
  • Platelet-derived growth factor receptor beta
  • Receptor tyrosine-protein kinase erbB-2
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
31 IC50
  • Anilinoquinazoline deriv. 9
  • CHEMBL301018
  • N-(3-chloro-4-fluorophenyl)-6,7-dimethoxyquinazolin-4-amine
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 3A
  • D(2) dopamine receptor
  • Integrin alpha-5/Neuronal acetylcholine receptor subunit alpha-3/Neuronal acetylcholine receptor subunit beta-2/Neuronal acetylcholine receptor subunit beta-4
  • Multidrug and toxin extrusion protein 1
  • Multidrug and toxin extrusion protein 2
  • Neuronal acetylcholine receptor Alpha-4/Beta-2
  • Neuronal nicotinic acetylcholine receptor
  • Potassium voltage-gated channel subfamily H member 2
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Serotonin 2 (5-HT2) receptor
  • Serotonin 3 receptor (5HT3)
  • Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
  • Serotonin 4 (5-HT4) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Solute carrier family 22 member 2
26 Ki 10 IC50 2 Kd
  • (BRL 43694)1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide
  • (granisetron)1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide
  • 1-Methyl-1H-indazole-3-carboxylic acid (8-methyl-8-aza-bicyclo[3.2.1]oct-3-yl)-amide
  • 1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide
  • 1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide(BRL 43694)
  • 1-Methyl-1H-indazole-3-carboxylic acid (9-methyl-9-aza-bicyclo[3.3.1]non-3-yl)-amide(Granisetron)
  • 1-methyl-N-((1S,5R)-9-methyl-9-aza-bicyclo[3.3.1]nonan-3-yl)-1H-indazole-3-carboxamide
  • 2-(9-Methyl-3,9-diaza-bicyclo[3.3.1]non-3-yl)-1-(1-methyl-1H-indol-3-yl)-ethanone(Granisetron)
  • BRL 43694
  • BRL-43694
  • CHEMBL519643
  • GRANISETRON
  • LY-278584
  • GRM7
  • GRM8
  • Glutamate receptor ionotropic, NMDA 1
  • Metabotropic glutamate receptor
  • Metabotropic glutamate receptor 1
  • Metabotropic glutamate receptor 2
  • Metabotropic glutamate receptor 3
  • Metabotropic glutamate receptor 4
  • Metabotropic glutamate receptor 4 (mGlu4)
  • Metabotropic glutamate receptor 4 (mGluR4)
  • Metabotropic glutamate receptor 5
  • Metabotropic glutamate receptor 6
  • Metabotropic glutamate receptor 6 (mGlu6)
  • Metabotropic glutamate receptor 7
  • Metabotropic glutamate receptor 7 (mGlu7)
  • Metabotropic glutamate receptor 8
  • Metabotropic glutamate receptor 8 (mGlu8)
21 Ki 76 EC50
  • (S)-2-Amino-4-phosphono-butyric acid
  • (S)-2-amino-4-phosphonobutanoic acid
  • 2-Amino-3-(3,5-dioxo-[1,2,4]oxadiazolidin-2-yl)-propionic acid
  • 2-Amino-4-phosphono-butyric acid
  • 2-Amino-4-phosphono-butyric acid(S-AP4)
  • 2-amino-4-phosphonobutanoic acid
  • 2-amino-4-phosphonobutyric acid
  • CHEMBL33567
  • L-(+)-2-amino-4-phosphonobutyric acid
  • L-1-amino-4-phosphonobutanoic acid
  • L-AP4
  • L-APB
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 15
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • DNA topoisomerase II
  • Glutamate receptor ionotropic, NMDA 1
  • Ornithine decarboxylase
  • Phosphodiesterase 1
16 Ki 2 IC50
  • 1,5,10-triazadecane
  • 4-azaoctamethylenediamine
  • 4-azaoctane-1,8-diamine
  • CHEMBL19612
  • N-(3-aminopropyl)butane-1,4-diamine
  • spermidine
  • 10 kDa chaperonin
  • 60 kDa chaperonin
  • Amine oxidase (flavin-containing) A
  • Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7)
  • Dual specificity phosphatase Cdc25A
  • Dual specificity phosphatase Cdc25B
  • HIF1A/p300/CREB-binding protein
  • HSP60/HSP10
  • Histone acetyltransferase KAT2A/KAT2B
  • Histone acetyltransferase PCAF
  • Histone acetyltransferase p300
  • Mitogen-activated protein kinase kinase kinase 14
  • Monoamine oxidase B (MAO-B)
  • Receptor tyrosine-protein kinase erbB-2
  • Thiosulfate sulfurtransferase
  • Transient receptor potential cation channel subfamily A member 1
  • Trypanothione reductase
20 IC50 1 Kd 2 EC50
  • 5-Hydroxy-2-methyl-[1,4]naphthoquinone
  • 5-hydroxy-2-methylnaphthalene-1,4-dione
  • CHEMBL295316
  • Plumbagin (6b)
  • Pumbagin
  • plumbagin
  • Beta tubulin
  • Bile salt export pump (BSEP)
  • Cytochrome P450 3A
  • Monoamine oxidase
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Multidrug resistance-associated protein 2 (MRP2)
  • P-glycoprotein (P-gp)
  • P-glycoprotein 1
  • P-glycoprotein 1 and 3 (MDR1a/MDR1b)
  • Reverse transcriptase
  • Similar to alpha-tubulin isoform 1
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Solute carrier organic anion transporter family member 1B3 (OATP1B3)
  • Steroidogenic Factor 1
  • Tubulin
  • Tubulin beta chain
  • nuclear receptor subfamily 0 group B member 1
11 Ki 36 IC50 1 Kd 2 EC50
  • (2ALPHA,2''BETA,3BETA,4ALPHA,5BETA)-VINCALEUKOBLASTINE
  • CHEMBL159
  • VINBLASTINE
  • VINBLASTINE SULFATE
  • cid_5388983
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Multidrug and toxin extrusion protein 1
  • Multidrug resistance-associated protein 4
  • Potassium channel protein TASK-1
  • Potassium channel subfamily K member 18
  • Potassium voltage-gated channel subfamily D member 2
  • Potassium voltage-gated channel subfamily H member 2
  • Sodium channel alpha subunit
  • Sodium channel protein type 5 subunit alpha
  • Sodium channel protein type 9 subunit alpha
  • Sodium channel protein type I I alpha subunit
  • Twik-RElated Potassium (K+) channel 1 (TREK1)
  • Voltage-gated L-type calcium channel alpha-1C subunit
  • Voltage-gated potassium channel subunit Kv1.5
21 IC50
1 ΔG°
  • 2-(Diethylamino)-2',6'-acetoxylidide
  • 2-(Diethylamino)-N-(2,6-dimethylphenyl)acetamide
  • CHEMBL79
  • Dalcaine
  • LIDOCAINE
  • Lignocaine
  • N-(2,6-dimethylphenyl)-N(2),N(2)-diethylglycinamide
  • Octocaine
  • SAMPL3, G5
  • 10 kDa chaperonin
  • 60 kDa chaperonin
  • Adrenergic Alpha
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Beta-2 adrenergic receptor
  • Bile salt export pump
  • D(2) dopamine receptor
  • DRD1
  • Dopamine receptor
  • HSP60/HSP10
  • Serotonin (5-HT) receptor
  • Sodium channel protein type I I alpha subunit
  • Solute carrier family 22 member 2
  • Solute carrier family 22 member 3
  • Thiosulfate sulfurtransferase
11 Ki 11 IC50
  • Benzyl-(2-chloro-ethyl)-(1-methyl-2-phenoxy-ethyl)-amine
  • CHEMBL753
  • Dibenzyline
  • PHENOXYBENZAMINE
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIII
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Human herpesvirus 1 DNA polymerase
  • Human immunodeficiency virus type 1 reverse transcriptase
  • Multidrug resistance-associated protein 4
14 Ki 7 IC50
  • (phosphonoformate)Trisodium phosphonoformate
  • Antiviral agent : Inhibitor of reverse transcriptase of Human T-cell lymphotropic, virus type III, useful in the treatment of HSV-1 infections
  • CHEMBL754
  • EHB-776
  • FOSCARNET SODIUM
  • Foscarnet
  • Foscavir
  • phosphonoformate trisodium salt
  • trisodium dioxidophosphinecarboxylate oxide
  • trisodium dioxidophosphinecarboxylate oxide with 6 molecules of water(foscarnet)
  • trisodium phosphonoformate
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-dependent kinase 2
  • Fibroblast growth factor receptor 3
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • MAP kinase-activated protein kinase 5
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase kinase kinase 7
  • Non-receptor tyrosine-protein kinase TYK2
  • PTK2B protein tyrosine kinase 2 beta (PTK2B)
  • Rho-associated protein kinase 1
  • Serine/threonine-protein kinase RIPK2
  • Serine/threonine-protein kinase TBK1
  • Tyrosine-protein kinase JAK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase SYK
17 IC50
  • CHEMBL3360318
  • Adrenergic alpha1B
  • Adrenergic receptor alpha-2
  • Alpha adrenergic receptor 1A and 1B
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Bile salt export pump
  • Bile salt export pump (BSEP)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cerebral cortex alpha adrenergic receptor
  • Multidrug resistance-associated protein 4
  • Serotonin (5-HT) receptor
  • adrenergic Alpha2
18 Ki 6 IC50
  • CHEMBL279516
  • INDORAMIN
  • INDORAMINE
  • INDORAMINN-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide
  • N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide
  • N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide (Indoramin)
  • N-{1-[2-(1H-Indol-3-yl)-ethyl]-piperidin-4-yl}-benzamide(indoramin)
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Multidrug resistance-associated protein 4
  • PTGFR
  • Prostaglandin E2 receptor
  • Prostaglandin E2 receptor EP1 subtype (EP1)
  • Prostaglandin E2 receptor EP2 subtype
  • Prostaglandin E2 receptor EP4 subtype
  • Prostaglandin F2-alpha receptor
  • Prostaglandin Transporter
  • Prostaglandin transporter (PGT)
  • Prostanoid DP receptor
  • Prostanoid IP receptor
  • Prostanoid TP receptor
  • Solute carrier organic anion transporter family member 2A1
  • Solute carrier organic anion transporter family member 2B1
6 Ki 24 IC50 7 EC50
  • (5Z,13E,15S)-9alpha,11alpha,15-trihydroxyprosta-5,13-dien-1-oic acid
  • CHEMBL815
  • DINOPROST
  • PGF2alpha
  • l-PGF2-alpha
  • l-Prostaglandin F2-alpha
  • prostaglandin F2alpha
  • Acrosin
  • Coagulation factor III/Factor VIIa (fVIIa)
  • Coagulation factor X
  • Coagulation factor XI
  • Complement C1s
  • Glutamate delta 2
  • Kallikrein 5
  • Matriptase
  • Plasminogen
  • Prothrombin
  • Thrombin
  • Thrombin & trypsin
  • Tissue-type plasminogen activator
  • Trypsin
  • Trypsin II
  • Trypsin-1
  • Urokinase-type plasminogen activator
28 Ki 2 IC50 4 Kd
  • Benzamidine (Protonated)
  • CHEMBL20936
  • CHEMBL537204
  • benzamidine
  • 72 kDa type IV collagenase
  • Adenosine receptor A3
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 7
  • Collagenase 3
  • Glycogen phosphorylase, muscle form
  • Lymphocyte differentiation antigen CD38
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-9
  • P-glycoprotein (P-gp)
  • Stromelysin-1
  • Tyrosine-protein kinase receptor FLT3
  • Urease subunit beta
  • Xanthine dehydrogenase/oxidase
7 Ki 11 IC50 1 Kd
  • (+/-) taxifolin
  • (+/-)-Dihydroquercetin
  • (+/-)-taxifolin
  • (2R,3R)-2-(3,4-Dihydroxy-phenyl)-3,5,7-trihydroxy-chroman-4-one
  • (2R,3R)-2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one
  • 2-(3,4-Dihydroxy-phenyl)-3,5,7-trihydroxy-chroman-4-one
  • 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxychroman-4-one
  • 3,5,7,3',4'-pentahydroxyflavanone
  • CHEMBL337309
  • NSC-2801
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401977
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401978
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401979
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401980
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401981
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401982
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401983
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401984
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401985
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401986
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401987
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401988
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401989
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401990
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401975
  • Cyclin-dependent kinase 2
  • Glycogen synthase kinase-3
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Proto-oncogene tyrosine-protein kinase Src
  • Rho-associated protein kinase 2/Rho-kinase (ROCK I)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
  • cAMP-dependent protein kinase (PKA)
17 Ki
  • CHEMBL3401976
  • Calcium channel (Type L)
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Neurokinin 2 receptor
  • Nuclear receptor subfamily 1 group I member 2
  • Phosphodiesterase 4
  • Potassium voltage-gated channel subfamily H member 2
  • Sodium channel protein type 5 subunit alpha
  • Somatostatin receptor 3
  • Somatostatin receptor subtype 3
  • Somatostatin receptor type 1
  • Somatostatin receptor type 2
  • Somatostatin receptor type 3
  • Somatostatin receptor type 4
  • Somatostatin receptor type 5
21 IC50 1 EC50
  • CHEMBL3582336
  • ATPase family AAA domain-containing protein 2
  • ATPase family AAA domain-containing protein 2B
  • Bromodomain adjacent to zinc finger domain protein 2B
  • Bromodomain-containing protein 2
  • Bromodomain-containing protein 2 Bromo 1 domain(BRD2 BD1)
  • Bromodomain-containing protein 2 Bromo 2 domain(BRD2 BD2)
  • Bromodomain-containing protein 3
  • Bromodomain-containing protein 3 Bromo 1 domain(BRD3 BD1)
  • Bromodomain-containing protein 3 Bromo 2 domain(BRD3 BD2)
  • Bromodomain-containing protein 4
  • Bromodomain-containing protein 4 Bromo 1 domain(BRD4 BD1)
  • CREB-binding protein
  • Myeloid/lymphoid or mixed-lineage leukemia (MLL)
  • Protein polybromo-1
  • Transcription activator BRG1
  • Transcription initiation factor TFIID subunit 1
  • Transcription intermediary factor 1-alpha
12 Ki 2 IC50 21 Kd
  • CHEMBL3581661
  • US9675697, Cpd. No. 23
  • ATPase family AAA domain-containing protein 2
  • Bromodomain adjacent to zinc finger domain protein 2A
  • Bromodomain adjacent to zinc finger domain protein 2B
  • Bromodomain testis-specific protein
  • Bromodomain-containing protein 2
  • Bromodomain-containing protein 3
  • Bromodomain-containing protein 4
  • Bromodomain-containing protein 7
  • Bromodomain-containing protein 8
  • Bromodomain-containing protein 9
  • Histone acetyltransferase KAT2A
  • Histone acetyltransferase PCAF
  • Nucleosome-remodeling factor subunit BPTF
  • Peregrin
  • Protein polybromo-1
  • Transcription initiation factor TFIID subunit 1
  • Tyrosine-protein kinase BAZ1B
8 IC50 19 Kd
  • CHEMBL3590405
  • Adrenergic receptor alpha-2
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Bile salt export pump
  • Calcium channel (Type L)
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 2J2
  • Cytochrome P450 3A
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Multidrug resistance-associated protein 4
  • Quinolone resistance protein norA
  • Voltage-dependent L-type calcium channel subunit alpha-1S
1 Ki 29 IC50
  • CHEBI:7550
  • NICARDIPINE
  • Nicardipine
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adenosine receptor A3
  • Adrenergic receptor alpha-1
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Histamine H1 receptor
  • Histamine H2 Receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Sodium-dependent dopamine transporter
  • Voltage-gated L-type calcium channel
17 IC50
  • 4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazine-1-carboxylic acid 2-(4-fluoro-phenyl)-ethyl ester
  • CHEMBL325516
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adrenergic receptor alpha-1
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Histamine H1 receptor
  • Histamine H2 Receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Sodium-dependent dopamine transporter
  • Voltage-gated L-type calcium channel
17 IC50
  • 1-{4-[4,4-Bis-(4-fluoro-phenyl)-butyl]-piperazin-1-yl}-4-phenyl-butan-1-one
  • CHEMBL117537
  • PTGER3
  • PTGER4
  • PTGFR
  • PTGIR
  • Peroxisome proliferator-activated receptor
  • Peroxisome proliferator-activated receptor alpha (PPAR alpha)
  • Peroxisome proliferator-activated receptor delta
  • Prostaglandin D Synthase
  • Prostaglandin E2 receptor
  • Prostaglandin E2 receptor EP1 subtype (EP1)
  • Prostaglandin E2 receptor EP2 subtype
  • Prostaglandin E2 receptor EP4 subtype
  • Prostaglandin F2-alpha receptor
  • Prostaglandin Transporter
  • Prostanoid EP2 Receptor
  • Prostanoid EP3 Receptor
  • Prostanoid IP receptor
18 Ki 5 EC50
  • 5-[(3aS,4R,5R,6aS)-5-Hydroxy-4-((S)-3-hydroxy-oct-1-enyl)-hexahydro-pentalen-(2Z)-ylidene]-pentanoic acid
  • 5-[5-Hydroxy-4-(3-hydroxy-oct-1-enyl)-hexahydro-pentalen-2-ylidene]-pentanoic acidCarbacyclin
  • CARBACYCLIN
  • CHEMBL148319
  • PGI2
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Dopamine D1 receptor
  • Histamine H1 receptor
  • Serotonin (5-HT) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
17 Ki 1 EC50
  • (2,4-Dimethyl-azetidin-1-yl)-(7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-9-yl)-methanone
  • CHEMBL137781
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Dopamine D1 receptor
  • Histamine H1 receptor
  • Serotonin (5-HT) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
17 Ki 1 EC50
  • (2,4-Dimethyl-azetidin-1-yl)-(7-methyl-4,6,6a,7,8,9-hexahydro-indolo[4,3-fg]quinolin-9-yl)-methanone
  • CHEMBL343755
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 3A
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Adrenergic receptor alpha-2
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
16 Ki 4 IC50 2 EC50
  • 1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine
  • CHEMBL133868
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 3A
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • Adrenergic receptor alpha-2
  • Alpha adrenergic receptor 1A and 1B
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
15 Ki 4 IC50 1 EC50
  • (S)-1-Methyl-2-(3,7,8,9-tetrahydro-pyrano[3,2-e]indol-1-yl)-ethylamine
  • CHEMBL133455
  • Ephrin type-A receptor 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Hepatocyte growth factor receptor
  • Insulin-like growth factor I receptor
  • Macrophage-stimulating protein receptor
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
17 IC50
  • CHEMBL3759079
  • 1,3-beta-glucan synthase component GLS2
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Histamine H2 receptor
  • Muscarinic acetylcholine receptor M5
  • Sodium-dependent serotonin transporter
32 Ki 1 IC50 10 EC50
  • CHEMBL3769968
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 7
  • Acetylcholinesterase and butyrylcholinesterase (AChE and BChE)
  • Adrenergic receptor alpha-1
  • Adrenergic receptor alpha-2
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Dopamine receptor
  • HTR1D
  • HTR4
  • HTR6
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sodium-dependent serotonin transporter
7 Ki 21 IC50 2 EC50
  • 5-{4-[4-(5-Cyano-1H-indol-3-yl)-butyl]-piperazin-1-yl}-benzofuran-2-carboxylic acid amide
  • CHEMBL439849
  • VILAZODONE
  • 5-lipoxygenase/FLAP
  • Acetylcholinesterase
  • Aldo-keto reductase family member 1B10 (AKR1B10)
  • Aldose reductase (AR)
  • Butyrylcholinesterase (BuChE)
  • Glycogen phosphorylase, muscle form
  • Hypoxia-inducible factor prolyl hydroxylase
  • Liver glycogen phosphorylase
  • Muscle glycogen phosphorylase
  • Prostaglandin E synthase/G/H synthase 2
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Protease
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase 1C
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Tyrosine-protein phosphatase non-receptor type 11
  • Tyrosine-protein phosphatase non-receptor type 2
2 Ki 19 IC50 2 EC50
  • 2alpha,3beta-dihydroxy-12-oleanen-28-oic acid
  • 2alpha,3beta-dihydroxy-olean-12-en-28-oic acid
  • CHEMBL201515
  • Maslinic acid
  • Maslinicacid
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2B
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 5A
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • Beta-1 adrenergic receptor
  • D(4) dopamine receptor
  • Mu-type opioid receptor
  • Potassium voltage-gated channel subfamily H member 2
  • Serotonin 3a (5-HT3a)/3b (5-HT3b)/3c (5-HT3c)/3d (5-HT3d)/3e (5-HT3e) receptor
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
17 Ki 1 IC50 2 EC50
  • (4R,9aR)-6-Cyclopropylmethoxymethyl-4-methyl-1,2,3,4,9,9a-hexahydro-2,4a,5-triaza-fluorene
  • CHEMBL203013
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-dependent kinase 2
  • Epidermal growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin receptor
  • Mitogen-activated protein kinase 3
  • Protein kinase C (PKC)
  • RAC-alpha serine/threonine-protein kinase
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase ZAP-70
  • cAMP-dependent protein kinase (PKA)
1 Ki 17 IC50
  • CHEMBL209148
  • N-(5-(5-(1-acetylpiperazine-4-carbonyl)-4-methoxy-2-methylphenylthio)thiazol-2-yl)-4-((3,3-dimethylbutan-2-ylamino)methyl)benzamide
  • 1,3-beta-glucan synthase component GLS2
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • DNA-PK/Ku70/Ku85
  • Phosphatidylinositol 3-kinase catalytic subunit type 3
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Phosphoinositide 3-Kinase (PI3K), delta
  • p110α/p85α
  • p110β/p85α
48 IC50 4 Kd
  • CHEMBL3984425
  • US10329299, Compound 21
  • US10675286, Compound 110
  • US9775844, Compound 4
  • 1,3-beta-glucan synthase component GLS2
  • 5-hydroxytryptamine receptor 3A
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Neuronal acetylcholine receptor
  • Neuronal acetylcholine receptor Alpha-3/Beta-4
  • Neuronal acetylcholine receptor Alpha-4/Beta-2
  • Neuronal acetylcholine receptor protein alpha-4/beta-2 subunit
  • Neuronal acetylcholine receptor protein alpha-7 subunit
  • Neuronal acetylcholine receptor; alpha3/beta4
  • Nicotinic acetylcholine receptor alpha-1/beta-1/delta/epsilon
  • Potassium voltage-gated channel subfamily H member 2
3 Ki 23 IC50 15 EC50
  • CHEMBL3918431
  • Apoptotic peptidase activating factor 1
  • Beta lactamase
  • Caspase-9
  • Cdc25C
  • Dual specificity mitogen-activated protein kinase kinase 7 (MAP2K7)
  • Dual specificity phosphatase Cdc25A
  • Dual specificity phosphatase Cdc25B
  • Dual specificity phosphatase Cdc25C
  • Phospholipase A2
  • Replicase polyprotein 1ab
  • TGM2/ Cdc25
  • Toll-like receptor 9
  • cysteine protease ATG4B isoform a
  • large T antigen
  • phosphatase Cdc25
  • putative hexokinase HKDC1
  • tyrosyl-DNA phosphodiesterase 2
25 IC50 1 Kd 1 EC50
  • 2,3-bis(2-hydroxyethylthio)naphthalene-1,4-dione
  • CHEMBL429095
  • N1786 (NSC95397)
  • NSC 95397
  • NSC-95397
  • cid_262093
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 4 (5-HT4)
  • Adrenergic receptor alpha
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Serotonin 1a (5-HT1a) receptor
  • Serotonin 3a (5-HT3a)/3b (5-HT3b) receptor
17 Ki
  • CHEMBL298612
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDK2/CycE
  • CDK7/Cyclin H/MNAT1
  • Cyclin-Dependent Kinase 1 (CDK1)
  • Cyclin-Dependent Kinase 2 (CDK2)
  • Cyclin-Dependent Kinase 4 (CDK4)
  • Cyclin-Dependent Kinase 5 (CDK5)
  • Cyclin-Dependent Kinase 7 (CDK7)
  • Cyclin-Dependent Kinase 9 (CDK9)
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent kinase 4
  • Cyclin-dependent kinase 7
  • Cyclin-dependent kinase 9
  • Tyrosine-protein kinase ABL1
15 Ki 7 IC50
  • (4-(2-Amino-4-methylthiazol-5-yl)pyrimidin-2-yl)-(3-nitrophenyl)amine
  • 4-methyl-5-(2-(3-nitrophenylamino)pyrimidin-4-yl)thiazol-2-amine
  • CHEMBL298445
  • [4-(2-AMINO-4-METHYL-THIAZOL-5-YL)-PYRIMIDIN-2-YL]-(3-NITRO-PHENYL)-AMINE
  • 3',5'-cyclic phosphodiesterase
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C8
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Phosphodiesterase 3 and 5 (PDE3 and PDE5)
  • Phosphodiesterase 6A
  • Phosphodiesterase 7
  • Phosphodiesterase 8
  • Potassium voltage-gated channel subfamily H member 2
  • cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
18 IC50
  • CHEMBL4099219
  • 1,3-beta-glucan synthase component GLS2
  • Axin-1/Glycogen synthase kinase-3 beta
  • CDK2/CycE
  • Casein kinase II subunit alpha'
  • Cyclin-dependent kinase 2
  • Cytoplasmic tyrosine-protein kinase BMX
  • Interleukin-1 receptor-associated kinase 4
  • Non-receptor tyrosine-protein kinase TYK2
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
  • Voltage-gated potassium channel
28 IC50
  • CHEMBL4094440
  • US10214511, Example 7
  • US10676460, Example 7
  • 1,3-beta-glucan synthase component GLS2
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Dual specificity protein kinase CLK1/CLK4
  • Dual specificity protein kinase CLK2
  • Dual specificity protein kinase CLK3
  • Interleukin-1 receptor-associated kinase 1
  • Interleukin-1 receptor-associated kinase 3
  • Interleukin-1 receptor-associated kinase 4
  • Interleukin-1 receptor-associated kinase-like 2
  • Serine/threonine-protein kinase haspin
  • Sodium channel protein type 5 subunit alpha
  • Voltage-gated potassium channel
  • Voltage-gated potassium channel beta subunit Mink
19 IC50 4 Kd
  • CHEMBL4064608
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • Adrenergic receptor beta
  • Beta-1 adrenergic receptor
  • Bile acid transporter
  • Cytochrome P450 2D1
  • Cytochrome P450 2D18
  • Cytochrome P450 2D2
  • Cytochrome P450 2D3
  • Cytochrome P450 2D6 (2D6)
  • P-glycoprotein 1
  • Serotonin 1 (5-HT1) receptor
  • Serotonin 1B/1D receptor
  • Serotonin 2 (5-HT2) receptor
  • Sodium channel protein type I I alpha subunit
11 Ki 8 IC50 1 Kd 1 EC50
  • (-)-(S)-Propranolol
  • 1-(ISOPROPYLAMINO)-3-(1-NAPHTHYLOXY)-2-PROPANOL
  • CHEMBL452861
  • PROPRANOLOL
  • S-(-)-propanolol
  • [2-Hydroxy-3-(naphthalen-1-yloxy)-propyl]-isopropyl-ammonium((-)-propranolol)
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Multidrug resistance-associated protein 4
  • Neuraminidase
  • Neuraminidase A
  • Neuraminidase B
  • Neuraminidase N1
  • Neuraminidase N3
  • Oligopeptide transporter small intestine isoform
  • P-glycoprotein 1
  • Sialidase
  • Sialidase 1
  • Sialidase 2
  • Sialidase 3
  • Sialidase 4
  • Solute carrier family 15 member 1
2 Ki 119 IC50
  • Oseltamivir
  • ethyl (3R,4R,5S)-5-amino-4-acetamido-3-(pentan-3-yloxy)cyclohex-1-ene-1-carboxylate
  • Cytochrome P450
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • Mono [ADP-ribose] polymerase PARP16
  • Poly [ADP-ribose] polymerase 1
  • Poly [ADP-ribose] polymerase 10
  • Poly [ADP-ribose] polymerase 12
  • Poly [ADP-ribose] polymerase 14
  • Poly [ADP-ribose] polymerase 15
  • Poly [ADP-ribose] polymerase 2
  • Poly [ADP-ribose] polymerase 4
  • Poly [ADP-ribose] polymerase tankyrase-1
  • Poly [ADP-ribose] polymerase tankyrase-2
  • Protein mono-ADP-ribosyltransferase PARP3
  • Tankyrase 1/2
34 IC50
  • CHEMBL4095003
  • Cytochrome P450 1A
  • Cytochrome P450 2B6
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6
  • Cytochrome P450 3A
  • GABA-A receptor; alpha-1/beta-2/gamma-2
  • Gamma-aminobutyric acid receptor subunit alpha-4/beta-2/delta
  • Gamma-aminobutyric acid receptor subunit alpha-4/beta3/delta
  • Inward rectifier potassium channel 2
  • Kv channel-interacting protein 2/Potassium voltage-gated channel subfamily D member 3
  • Melanin-concentrating hormone receptor 2/HERG
  • Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2
  • Sodium channel protein type 5 subunit alpha
  • Voltage-gated calcium channel
  • Voltage-gated potassium channel
  • Voltage-gated potassium channel beta subunit Mink/subunit Kv7.1
14 IC50 4 EC50
  • CHEMBL4105630
  • Aurora kinase A/Targeting protein for Xklp2
  • Axin-1/Glycogen synthase kinase-3 beta
  • Cyclin-dependent kinase 2
  • Hepatocyte growth factor receptor
  • Interleukin-1 receptor-associated kinase 4
  • Mitogen-activated protein kinase 10
  • Mitogen-activated protein kinase 14
  • Protein kinase C theta type
  • Proto-oncogene tyrosine-protein kinase Src
  • Serine/threonine-protein kinase PLK1
  • Serine/threonine-protein kinase pim-1
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 2
17 Ki
  • CHEMBL493169
  • N-(piperidin-4-yl)-3-(3-(trifluoromethyl)phenyl)-[1,2,4]triazolo[4,3-b]pyridazin-6-amine
  • Alkaline phosphatase placental-like
  • Alkaline phosphatase, tissue-nonspecific isozyme
  • Alpi
  • Ephrin type-B receptor 2
  • Epidermal growth factor receptor
  • Fibroblast growth factor receptor 1
  • Glucose 6-phosphate dehydrogenase (G6PD)
  • Hepatocyte growth factor receptor
  • Induced myeloid leukemia cell differentiation protein Mcl-1
  • Intestinal alkaline phosphatase
  • MPI protein
  • Mast/stem cell growth factor receptor Kit
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor tyrosine-protein kinase erbB-2
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase
13 IC50 4 EC50
  • (+)-haematoxylin
  • (+)-hematoxylin
  • (6aS,11bR)-7,11b-dihydrobenz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol
  • (6aS,11bR)-7,11b-dihydroindeno[2,1-c]chromene-3,4,6a,9,10(6H)-pentol
  • CHEMBL477197
  • Haematoxylin
  • cid_10603
  • cis-(+)-7,11b-dihydrobenz[b]indeno[1,2-d]pyran-3,4,6a,9,10(6H)-pentol
  • hydroxybrasilin
  • hydroxybrazilin
  • 72 kDa type IV collagenase
  • Disintegrin and metalloproteinase domain-containing protein 10 (ADAM10)
  • Disintegrin and metalloproteinase domain-containing protein 17
  • Disintegrin and metalloproteinase domain-containing protein 33
  • Disintegrin and metalloproteinase domain-containing protein 9 (ADAM9)
  • Interstitial collagenase
  • Matrix metalloproteinase (2 and 3)
  • Matrix metalloproteinase 12
  • Matrix metalloproteinase 14
  • Matrix metalloproteinase 15
  • Matrix metalloproteinase 7
  • Matrix metalloproteinase-12 (MMP12)
  • Matrix metalloproteinase-14 (MMP14)
  • Matrix metalloproteinase-7 (MMP7)
  • Matrix metalloproteinase-9
  • Neutrophil collagenase
  • Stromelysin-1
10 Ki 12 IC50
  • (6S,7S)-N-hydroxy-5-methyl-6-(4-(5-(trifluoromethyl)pyridin-2-yl)piperazine-1-carbonyl)-5-azaspiro[2.5]octane-7-carboxamide
  • CHEMBL497985
  • 1,3-beta-glucan synthase component GLS2
  • Cytoplasmic tyrosine-protein kinase BMX
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor protein-tyrosine kinase erbB-4
  • SRC
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase Yes
18 IC50
  • CHEMBL4060757
  • 1,3-beta-glucan synthase component GLS2
  • Cytoplasmic tyrosine-protein kinase BMX
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor protein-tyrosine kinase erbB-4
  • SRC
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase Yes
18 IC50
  • CHEMBL4075954
  • 1,3-beta-glucan synthase component GLS2
  • Cytoplasmic tyrosine-protein kinase BMX
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor protein-tyrosine kinase erbB-4
  • SRC
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase Yes
18 IC50
  • CHEMBL4069387
  • 1,3-beta-glucan synthase component GLS2
  • Cytoplasmic tyrosine-protein kinase BMX
  • Proto-oncogene tyrosine-protein kinase Src
  • Receptor protein-tyrosine kinase erbB-4
  • SRC
  • Tyrosine-protein kinase BRK
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase CSK
  • Tyrosine-protein kinase FRK
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase Yes
18 IC50
  • CHEMBL4077588
  • ATP-binding cassette sub-family G member 2
  • BDNF/NT-3 growth factors receptor
  • CDK2/Cyclin E/G1/S-specific cyclin E2
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Ephrin type-A receptor 2 (EPHA2)
  • High affinity nerve growth factor receptor
  • Insulin receptor
  • Insulin-like growth factor 1 receptor
  • Insulin-like growth factor I receptor
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Potassium voltage-gated channel subfamily H member 2
  • RAC-alpha serine/threonine-protein kinase
  • Serine/threonine-protein kinase LMTK3
21 IC50 1 Kd
  • (S)-1-(4-(5-cyclopropyl-1H-pyrazol-3-ylamino)pyrrolo[1,2-f][1,2,4]triazin-2-yl)-N-(6-fluoropyridin-3-yl)-2-methylpyrrolidine-2-carboxamide
  • 1-{4-[(3-cyclopropyl-1H-pyrazol-5-yl)amino]pyrrolo[2,1-f][1,2,4]triazin-2-yl}-N-(6-fluoropyridin-3-yl)-2-methyl-L-prolinamide
  • BMS-754807
  • CHEMBL575448
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B
  • Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C
  • Homo sapiens phosphodiesterase 2A (PDE2A)
  • Phosphodiesterase 11A (PDE11A)
  • Phosphodiesterase 3 (PDE3)
  • Phosphodiesterase 6A
  • Phosphodiesterase 7
  • Phosphodiesterase 8
  • Phosphodiesterase 9A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4A
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4B
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4C isoform 1
  • cAMP-specific 3',5'-cyclic phosphodiesterase 4D
  • cAMP-specific 3',5'-cyclic phosphodiesterase 7B
  • cGMP-inhibited 3',5'-cyclic phosphodiesterase B
  • cGMP-specific 3',5'-cyclic phosphodiesterase
20 IC50
  • 3-[(trans-4-hydroxycyclohexyl)amino]-7-(6-methoxypyridin-3-yl)-1-(2-propoxyethyl)pyrido[3,4-b]pyrazin-2(1H)-one
  • CHEMBL567470
  • Angiopoietin-1 receptor
  • Aurora B/Incenp
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Aurora-C/INCENP
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Ferrochelatase R115L (FECH)
  • Fibroblast growth factor receptor 1
  • Serine/threonine-protein kinase Aurora-C
  • Serine/threonine-protein kinase SIK1
  • Targeting protein for Xklp2
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 3
8 Ki 16 IC50 1 Kd
  • 3-(4-(4-(2-(3-((dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea
  • 4-[3-(4-N,N-Dimethylcarbamylaminophenyl)-1-ethyl-1H-pyrazol-4-yl]-2-[3-(dimethylaminomethyl)phenyl]-1H-pyrrolo[2,3-b]-pyridine
  • CHEMBL1090479
  • GSK-1070916
  • 5-hydroxytryptamine receptor 2A (5HT2A)
  • Bile salt export pump
  • Carbonic Anhydrase III
  • Carbonic Anhydrase VA
  • Carbonic Anhydrase VB
  • Carbonic Anhydrase XIV
  • Carbonic anhydrase 1
  • Carbonic anhydrase 12
  • Carbonic anhydrase 13 (CA XIII)
  • Carbonic anhydrase 15
  • Carbonic anhydrase 2
  • Carbonic anhydrase 4
  • Carbonic anhydrase 6 (CA-VI)
  • Carbonic anhydrase 7
  • Carbonic anhydrase 9
  • Mu-type opioid receptor
  • Solute carrier family 22 member 1
13 Ki 3 IC50 2 EC50
  • 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol
  • 4-{2-[3-(4-Hydroxy-phenyl)-1-methyl-propylamino]-ethyl}-benzene-1,2-diol(Dobutamine)
  • CHEMBL926
  • DOBUTAMINE
  • Dobutrex
  • cid_36811
  • Aurora kinase B
  • Cyclin-dependent kinase 1
  • Cyclin-dependent kinase 2
  • Cyclin-dependent-like kinase 5
  • Ephrin type-B receptor 4
  • Epidermal growth factor receptor
  • Hepatocyte growth factor receptor
  • Insulin-like growth factor I receptor
  • Mitogen-activated protein kinase 3
  • Mitogen-activated protein kinase 9
  • RAC-alpha serine/threonine-protein kinase
  • Ribosomal protein S6 kinase (P70S6K)
  • Serine/threonine-protein kinase PLK1
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase ZAP-70
17 IC50 1 EC50
  • CHEMBL1243200
  • N-(4-(3-(2-(Methylamino)pyrimidin-4-yl)pyridin-2-yloxy)phenyl)-2-(phenylamino)benzamide
  • ALK tyrosine kinase receptor
  • Dual specificity mitogen-activated protein kinase kinase 1
  • Dual specificity mitogen-activated protein kinase kinase 2
  • Ephrin type-B receptor 4
  • MAP kinase-activated protein kinase 5
  • MAP kinase-interacting serine/threonine-protein kinase 2
  • Mast/stem cell growth factor receptor Kit
  • Mitogen-activated protein kinase 1
  • Non-receptor tyrosine-protein kinase TYK2
  • Platelet-derived growth factor receptor alpha
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 3
19 IC50
  • (S)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
  • (S,Z)-16-hydroxy-14-methoxy-3-methyl-3,4,9,10,11,12-hexahydro-1H-benzo[c][1]oxacyclotetradecine-1,7(8H)-dione
  • CHEMBL1651523
  • CDC2-like kinase 3 (CLK3)
  • CDK2/CycE
  • Casein kinase II alpha'/ beta
  • Casein kinase II subunit alpha
  • Casein kinase II subunit alpha 3
  • Casein kinase II subunit alpha'
  • Casein kinase II subunit beta (CK2 beta)
  • Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
  • Death-associated protein kinase 3
  • Dual specificity protein kinase CLK2
  • Dual specificity tyrosine-phosphorylation-regulated kinase 1B
  • Dual-specificity tyrosine-phosphorylation regulated kinase 1A
  • Homeodomain-interacting protein kinase 3
  • Serine/threonine-protein kinase TBK1
  • Serine/threonine-protein kinase pim-1
  • Serine/threonine-protein kinase pim-2
  • Tyrosine-protein kinase receptor FLT3
2 Ki 51 IC50 2 Kd 4 EC50
  • 5-(3-Chlorophenylamino)benzo[c][2,6]naphthyridine-8-carboxylic acid
  • 5-[(3-chlorophenyl)amino]benzo[c][2,6]naphthyridine-8-carboxylic acid
  • CHEMBL1230165
  • US9062043, Table 13, Compound 17
  • US9062043, Table 20b, Compound 12
  • DNA-PK/Ku70/Ku85
  • DNA-dependent protein kinase
  • Phosphatidylinositol 3-kinase catalytic subunit type 3
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform
  • Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform
  • Phosphatidylinositol 4-kinase alpha (PI4KA)
  • Phosphatidylinositol 4-kinase beta
  • Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha
  • Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta
  • Phosphoinositide 3-Kinase (PI3K), delta
  • Serine-protein kinase ATM
  • Serine/threonine-protein kinase ATR
  • Serine/threonine-protein kinase mTOR (mTOR)
  • Target of rapamycin complex 2 subunit MAPKAP1
  • Target of rapamycin complex subunit LST8
  • mTOR/FKBP12A/FKBP12B
  • p110α/p85α
12 IC50 6 EC50
  • 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one
  • CHEMBL1765602
  • BRAF/CRAF
  • EBifunctional epoxide hydrolase 2
  • Ephrin type-A receptor 2 (EPHA2)
  • Fibroblast growth factor receptor 1
  • Glycine receptor subunit alpha-1
  • Mast/stem cell growth factor receptor Kit
  • Platelet-derived growth factor receptor beta
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • RAF proto-oncogene serine/threonine-protein kinase
  • RET kinase mutant (V804L)
  • RET kinase mutant (V804M)
  • Serine/threonine-protein kinase B-raf
  • Tyrosine-protein kinase receptor FLT3
  • Vascular endothelial growth factor receptor 1
  • Vascular endothelial growth factor receptor 2
  • Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2)
  • Vascular endothelial growth factor receptor 3
1 Ki 31 IC50 1 Kd 1 EC50
  • CHEMBL1946170
  • REGORAFENIB
  • US10183928, Regorafenib
  • US10202365, Compound Regorafenib
  • US10227329, Compound Regorafenib
  • US10464902, Regorafenib
  • US10584114, Compound Regorafenib
  • US10774070, Compound Regorafenib
  • Aurora kinase B
  • CDK2/Cyclin A/Cyclin A1
  • Casein kinase I
  • Cyclin B/Cyclin-Dependent Kinase 1 (CDK1)/G2/mitotic-specific cyclin B2/G2/mitotic-specific cyclin B3
  • MAP kinase-activated protein kinase 2
  • Mitogen-activated protein kinase 1
  • Mitogen-activated protein kinase 14
  • Mitogen-activated protein kinase kinase kinase kinase 2
  • Platelet-derived growth factor receptor alpha
  • Protein kinase C alpha type
  • Proto-oncogene tyrosine-protein kinase Src
  • Ribosomal protein S6 kinase alpha 1
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase Lck
  • Vascular endothelial growth factor receptor 2
17 IC50
  • CHEMBL1163016
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • Alpha-2A adrenergic receptor
  • Alpha-2C adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • GPR145
  • GPR24
  • Melanin-concentrating hormone receptor
  • Melanin-concentrating hormone receptor 1
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • Potassium voltage-gated channel subfamily H member 2
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
13 Ki 8 IC50
  • CHEMBL2032049
  • Cereblon/Histone deacetylase 6
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Histone deacetylase 1
  • Histone deacetylase 10
  • Histone deacetylase 11
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Potassium voltage-gated channel subfamily H member 2
17 IC50
  • CHEMBL2177582
  • Cereblon/Histone deacetylase 6
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Histone deacetylase 1
  • Histone deacetylase 10
  • Histone deacetylase 11
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Potassium voltage-gated channel subfamily H member 2
17 IC50
  • CHEMBL2177588
  • Cereblon/Histone deacetylase 6
  • Cytochrome P450 1A
  • Cytochrome P450 2C19
  • Cytochrome P450 2C9
  • Cytochrome P450 2D6 (2D6)
  • Cytochrome P450 3A
  • Histone deacetylase 1
  • Histone deacetylase 10
  • Histone deacetylase 11
  • Histone deacetylase 2
  • Histone deacetylase 3
  • Histone deacetylase 4
  • Histone deacetylase 5
  • Histone deacetylase 7
  • Histone deacetylase 8
  • Histone deacetylase 9
  • Potassium voltage-gated channel subfamily H member 2
17 IC50
  • CHEMBL2177587
  • Dual specificity protein phosphatase (VHR)
  • Dual specificity protein phosphatase CDC14A
  • Dual specificity protein phosphatase VHX (VHX)
  • Fas-associated protein-tyrosine phosphatase 1 (FAP1)
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Laforin
  • Leukocyte common antigen
  • Low molecular weight phosphotyrosine protein phosphatase
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase 1C
  • Protein-tyrosine phosphatase MEG2 (PTP-Meg2)
  • Protein-tyrosine phosphatase alpha
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Receptor-type tyrosine-protein phosphatase gamma
  • Tyrosine-protein phosphatase non-receptor type 11
  • Tyrosine-protein phosphatase non-receptor type 2
18 IC50
  • CHEMBL2316907
  • Dual specificity protein phosphatase (VHR)
  • Dual specificity protein phosphatase CDC14A
  • Dual specificity protein phosphatase VHX (VHX)
  • Fas-associated protein-tyrosine phosphatase 1 (FAP1)
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Laforin
  • Leukocyte common antigen
  • Low molecular weight phosphotyrosine protein phosphatase
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase 1C
  • Protein-tyrosine phosphatase MEG2 (PTP-Meg2)
  • Protein-tyrosine phosphatase alpha
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Receptor-type tyrosine-protein phosphatase gamma
  • Tyrosine-protein phosphatase non-receptor type 11
  • Tyrosine-protein phosphatase non-receptor type 2
18 IC50
  • CHEMBL2316902
  • Dual specificity protein phosphatase (VHR)
  • Dual specificity protein phosphatase CDC14A
  • Dual specificity protein phosphatase VHX (VHX)
  • Fas-associated protein-tyrosine phosphatase 1 (FAP1)
  • Hematopoietic cell protein-tyrosine phosphatase 70Z-PEP
  • Hematopoietic protein-tyrosine phosphatase (HEPTP)
  • Laforin
  • Leukocyte common antigen
  • Low molecular weight phosphotyrosine protein phosphatase
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase 1C
  • Protein-tyrosine phosphatase MEG2 (PTP-Meg2)
  • Protein-tyrosine phosphatase alpha
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Receptor-type tyrosine-protein phosphatase gamma
  • Tyrosine-protein phosphatase non-receptor type 11
  • Tyrosine-protein phosphatase non-receptor type 2
18 IC50
  • CHEMBL2316906
  • CaM kinase IV
  • Casein kinase I isoform delta
  • Hepatocyte growth factor receptor
  • Inhibitor of nuclear factor kappa-B kinase subunit beta
  • Insulin-like growth factor I receptor
  • Interleukin-1 receptor-associated kinase 4
  • MAP kinase-activated protein kinase 2
  • Mitogen-activated protein kinase 1
  • RAC-alpha serine/threonine-protein kinase
  • Rho-associated protein kinase 2
  • Serine/threonine-protein kinase Chk1/2
  • Serine/threonine-protein kinase MST2
  • Serine/threonine-protein kinase Nek2
  • Serine/threonine-protein kinase PLK3
  • Testis-specific serine/threonine-protein kinase 2
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase receptor FLT3
17 IC50
  • CHEMBL2385543
  • ALK tyrosine kinase receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Epidermal growth factor receptor
  • Epithelial discoidin domain-containing receptor 1
  • Hepatocyte growth factor receptor
  • Mast/stem cell growth factor receptor Kit
  • Platelet-derived growth factor receptor
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • RAC-alpha serine/threonine-protein kinase
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 2
  • mTOR/FKBP12A/FKBP12B
19 IC50
  • CHEMBL4218175
  • ALK tyrosine kinase receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Aurora kinase B
  • Epidermal growth factor receptor
  • Epithelial discoidin domain-containing receptor 1
  • Hepatocyte growth factor receptor
  • Mast/stem cell growth factor receptor Kit
  • Platelet-derived growth factor receptor
  • Proto-oncogene tyrosine-protein kinase Src
  • Proto-oncogene tyrosine-protein kinase receptor Ret
  • RAC-alpha serine/threonine-protein kinase
  • Tyrosine-protein kinase Mer
  • Tyrosine-protein kinase receptor FLT3
  • Tyrosine-protein kinase receptor TYRO3
  • Tyrosine-protein kinase receptor UFO
  • Vascular endothelial growth factor receptor 2
  • mTOR/FKBP12A/FKBP12B
19 IC50
  • CHEMBL4208852
  • 1,3-beta-glucan synthase component GLS2
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 6
  • Adrenergic receptor alpha-2
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • Histamine H1 receptor
  • Histamine H3 receptor
  • Muscarinic acetylcholine receptor M1
  • Serotonin (5-HT) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma-1 receptor
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
16 Ki 7 IC50
  • CHEMBL4293999
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M1 and M3
  • Muscarinic acetylcholine receptor M2 and M5
18 Ki 1 IC50 2 EC50
  • CHEMBL4442460
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • Alpha-1A adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Muscarinic acetylcholine receptor M1
  • Muscarinic acetylcholine receptor M1 and M3
  • Muscarinic acetylcholine receptor M2 and M5
18 Ki 1 IC50 2 EC50
  • CHEMBL4544086
  • Calmodulin/Proto-oncogene tyrosine-protein kinase Src
  • Cytoplasmic tyrosine-protein kinase BMX
  • Epidermal growth factor receptor
  • Receptor protein-tyrosine kinase erbB-4
  • Receptor tyrosine-protein kinase erbB-2
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase Blk
  • Tyrosine-protein kinase Fgr
  • Tyrosine-protein kinase Fyn
  • Tyrosine-protein kinase HCK
  • Tyrosine-protein kinase ITK/TSK
  • Tyrosine-protein kinase JAK3
  • Tyrosine-protein kinase Lck
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase TEC
  • Tyrosine-protein kinase TXK
  • Tyrosine-protein kinase Yes
17 IC50
  • CHEMBL4525187
  • 20S proteasome
  • Angiotensin-converting enzyme
  • Apoptotic protease-activating factor 1/Caspase-3/Caspase-9/Cytochrome c
  • Calpain1/2
  • Caspase
  • Caspase-2
  • Caspase-3
  • Cathepsin B
  • Cathepsin D
  • Cathepsin G
  • Endothelin-converting enzyme 1
  • Interstitial collagenase
  • Leukocyte elastase
  • Matrix metalloproteinase (2 and 3)
  • Matrix metalloproteinase-9
  • Tryptase
  • cysteine protease ATG4B isoform a
19 IC50
  • CHEMBL4590201
  • 20S proteasome
  • Angiotensin-converting enzyme
  • Apoptotic protease-activating factor 1/Caspase-3/Caspase-9/Cytochrome c
  • Calpain1/2
  • Caspase
  • Caspase-2
  • Caspase-3
  • Cathepsin B
  • Cathepsin D
  • Cathepsin G
  • Endothelin-converting enzyme 1
  • Interstitial collagenase
  • Leukocyte elastase
  • Matrix metalloproteinase (2 and 3)
  • Matrix metalloproteinase-9
  • Tryptase
  • cysteine protease ATG4B isoform a
19 IC50
  • CHEMBL4520267
  • 20S proteasome
  • Angiotensin-converting enzyme
  • Apoptotic protease-activating factor 1/Caspase-3/Caspase-9/Cytochrome c
  • Calpain1/2
  • Caspase
  • Caspase-2
  • Caspase-3
  • Cathepsin B
  • Cathepsin D
  • Cathepsin G
  • Endothelin-converting enzyme 1
  • Interstitial collagenase
  • Leukocyte elastase
  • Matrix metalloproteinase (2 and 3)
  • Matrix metalloproteinase-9
  • Tryptase
  • cysteine protease ATG4B isoform a
19 IC50
  • CHEMBL2402203
  • Alkaline phosphatase placental-like
  • Alkaline phosphatase, tissue-nonspecific isozyme
  • Alpi
  • Apoptotic peptidase activating factor 1
  • Caspase-9
  • Intestinal alkaline phosphatase
  • POsterior Segregation family member (pos-1)
  • Phospholipase C, gamma 1
  • Phospholipase C-beta-3
  • RecName: Full=Zinc finger protein mex-5
  • SUMO1 activating enzyme subunit 1
  • cardiac alpha tropomyosin
  • lens epithelium-derived growth factor p75
  • nuclear receptor corepressor 2 isoform 2
  • photoreceptor-specific nuclear receptor
  • ubiquitin-conjugating enzyme E2 N
  • ubiquitin-conjugating enzyme E2I
17 IC50 2 EC50
  • 2-[(5Z)-5-[(E)-3-(2-furanyl)prop-2-enylidene]-4-oxo-2-sulfanylidene-3-thiazolidinyl]butanedioic acid
  • 2-[(5Z)-5-[(E)-3-(2-furyl)prop-2-enylidene]-4-keto-2-thioxo-thiazolidin-3-yl]succinic acid
  • 2-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxidanylidene-2-sulfanylidene-1,3-thiazolidin-3-yl]butanedioic acid
  • 2-[(5Z)-5-[(E)-3-(furan-2-yl)prop-2-enylidene]-4-oxo-2-sulfanylidene-1,3-thiazolidin-3-yl]butanedioic acid
  • 2-{5-[(E)-3-Furan-2-yl-prop-2-en-(Z)-ylidene]-4-oxo-2-thioxo-thiazolidin-3-yl}-succinic acid
  • MLS000778634
  • SMR000415428
  • cid_5994065
  • Acetylcholinesterase
  • Acyl-CoA: cholesterol acyltransferase (ACAT)
  • Carboxylesterase 2
  • Leukocyte common antigen
  • POsterior Segregation family member (pos-1)
  • Papain
  • Papain-like protease (PLpro)
  • Protein-tyrosine phosphatase 1B
  • Protein-tyrosine phosphatase 1C
  • Protein-tyrosine phosphatase MEG2 (PTP-Meg2)
  • RecName: Full=Zinc finger protein mex-5
  • Receptor-type tyrosine-protein phosphatase F (LAR)
  • Signal transducer and activator of transcription 3
  • Tyrosine-protein phosphatase non-receptor type 11
  • Tyrosine-protein phosphatase non-receptor type 2
  • karyopherin alpha 2 (RAG cohort 1, importin alpha 1), isoform CRA_b
  • mRNA interferase toxin, antitoxin is MazE
6 Ki 14 IC50 5 EC50
  • (5Z)-3-allyl-5-(3-ethyl-1,3-benzothiazol-2-ylidene)-2-thioxo-thiazolidin-4-one
  • (5Z)-5-(3-ethyl-1,3-benzothiazol-2-ylidene)-3-prop-2-enyl-2-sulfanylidene-1,3-thiazolidin-4-one
  • (5Z)-5-(3-ethyl-1,3-benzothiazol-2-ylidene)-3-prop-2-enyl-2-sulfanylidene-4-thiazolidinone
  • 3-Allyl-5-(3-ethyl-3H-benzothiazol-2-ylidene)-2-thioxo-thiazolidin-4-one
  • MLS001210616
  • SMR000505156
  • cid_3094418
  • ADRA2C
  • Adenosine receptor A2b
  • Adrenergic receptor alpha-1
  • Adrenergic receptor alpha-2
  • Alpha-2A adrenergic receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • D(1A) dopamine receptor
  • D(1B) dopamine receptor
  • D(2) dopamine receptor
  • DRD2
  • Dopamine D1B
  • G-protein subunit alpha-16
  • Histone Lysine Demethylase
  • Multidrug resistance-associated protein 4
  • trace amine-associated receptor 1
20 Ki 8 IC50 5 Kd 5 EC50
  • 9-chloranyl-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid
  • 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;mesylic acid
  • 9-chloro-5-(4-hydroxyphenyl)-2,3,4,5-tetrahydro-1H-3-benzazepine-7,8-diol;methanesulfonic acid
  • FENOLDOPAM
  • FENOLDOPAM MESYLATE
  • MLS001401388
  • SMR000469190
  • cid_49659
  • CDC2-like kinase 3 (CLK3)
  • Casein kinase I
  • Casein kinase I isoform delta
  • Casein kinase I isoform epsilon
  • Casein kinase I isoform gamma-3
  • DNA dC->dU-editing enzyme APOBEC-3G
  • Dual specificity protein kinase CLK1
  • Dual specificity protein kinase CLK2
  • Dual specificity protein kinase CLK3
  • Dual specificity protein kinase CLK4
  • Dual specificty protein kinase CLK1
  • Dual-specificity tyrosine-phosphorylation regulated kinase 1A
  • Dual-specificity tyrosine-regulated kinases 1B
  • SPS1/STE20-related protein kinase YSK4
  • Serine/threonine-protein kinase pim-1
  • Serine/threonine-protein kinase pim-3
  • probable DNA dC->dU-editing enzyme APOBEC-3A
12 IC50 13 Kd
  • (1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)-2-propanone
  • (1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)acetone
  • (1E)-1-(3-ethyl-5-methoxy-1,3-benzothiazol-2-ylidene)propan-2-one
  • CHEMBL408982
  • MLS000518915
  • SMR000129335
  • cid_1893667
  • 5-hydroxytryptamine receptor 1A
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Bile salt export pump
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • DRD1
  • DRD2
  • Dopamine D1 receptor
  • Dopamine receptor
  • Multidrug resistance-associated protein 4
  • Myeloperoxidase
  • Serotonin 1 (5-HT1) receptor
  • Serotonin 2 (5-HT2) receptor
43 Ki 10 IC50
  • CAS_15676-16-1
  • SULPIRIDE,(+)
  • Sulpiride-S
  • Sulpiride-l
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