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Compounds Sorted by Binding Targets per Compound

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429   443   447   515   
Compounds Sorted Alphabetically
Compound Name (alphabetical)
Binding Targets
Enz. Inhib. Data
ITC Data
Alternate Compound Names
  • 17-beta-Hydroxysteroid Dehydrogenase 5 (17-beta-HSD5, AKR1C3)
  • Aldo-keto reductase family 1 member C1
  • Aldo-keto reductase family 1 member C2
  • Aldo-keto reductase family 1 member C4 (AK1C4)
  • Aldo-keto-reductase family 1 member C3
  • Aldose reductase (ALR2)
  • Aldose reductase (AR)
  • Androgen Receptor
  • Arachidonate 5-lipoxygenase
  • Bile salt export pump
  • COX-1
  • COX-2
  • Canalicular multispecific organic anion transporter 2
  • Cannabinoid receptor 1
  • Cannabinoid receptor 2
  • Cyclooxygenase
  • Cyclooxygenase-1 (COX-1)
  • Cyclooxygenase-2 (COX-2)
  • Cyclooxygenase-2 mutant (R120Q)
  • Cyclooxygenase-2 mutant (S530A)
  • Cyclooxygenase-2 mutant (V349L)
  • Cyclooxygenase-2 mutant (V523I)
  • Cyclooxygenase-2 mutant (Y355F)
  • Cytochrome c oxidase subunit 2
  • Cytosolic phospholipase A2 gamma
  • Dehydrogenase/reductase SDR family member 9
  • EBifunctional epoxide hydrolase 2
  • Epidermal growth factor receptor
  • G protein-coupled receptor 44
  • Glyoxalase 1 (GLO1)
  • Interleukin-8
  • Multidrug and toxin extrusion protein 1
  • Multidrug resistance protein 1/Multidrug resistance associated protein 1
  • Multidrug resistance-associated protein 2 (MRP2)
  • Multidrug resistance-associated protein 4
  • Nitric Oxide Synthase, inducible
  • Nitric oxide synthase, inducible
  • PTGER2
  • Peroxisome proliferator-activated receptor
  • Phospholipase A2 group 1B
  • Phospholipase A2, major isoenzyme
  • Potassium voltage-gated channel subfamily H member 2
  • Prostaglandin E synthase
  • Prostaglandin E synthase/G/H synthase 2
  • Prostaglandin E2 receptor EP2 subtype
  • Prostaglandin G/H synthase (Cyclooxygenase-2)
  • Prostaglandin G/H synthase (cyclooxygenase)
  • Prostaglandin-H2 D-isomerase
  • Prostanoid DP receptor
  • Prostanoid EP1 Receptor
  • Prostanoid EP2 Receptor
  • Prostanoid EP3 Receptor
  • Prostanoid EP4 Receptor
  • Serum albumin
  • Serum paraoxonase/arylesterase 1
  • Solute carrier family 22 member 6
  • Solute carrier family 22 member 8
  • Solute carrier organic anion transporter family member 1A3
  • Solute carrier organic anion transporter family member 1B1 (OATP1B1)
  • Solute carrier organic anion transporter family member 1B3 (OATP1B3)
  • Solute carrier organic anion transporter family member 2B1
  • Thromboxane A2 Synthase (P450 TxA2)
  • Uracil nucleotide/cysteinyl leukotriene receptor
61 Ki 386 IC50 4 Kd 3 EC50
  • 2-{1-[(4-chlorophenyl)carbonyl]-5-methoxy-2-methyl-1H-indol-3-yl}acetic acid
  • CHEMBL6
  • Indocin
  • Indomethacin
  • US9271961, Indomethacin
  • indometacin
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 3A
  • Activin receptor-like kinase 2 (ALK-2)(aa 172-499)
  • Adenosine receptor A1
  • Alpha-1A adrenergic receptor
  • Aurora kinase A/Targeting protein for Xklp2
  • Axin-1/Glycogen synthase kinase-3 beta
  • Bile salt export pump (BSEP)
  • D(1A) dopamine receptor
  • DNA (cytosine-5)-methyltransferase 1 (DNMT1)
  • EZH1/PRC2
  • EZH2/SUZ12/EED/RBBP7/RBBP4
  • Estrogen receptor
  • Fibroblast growth factor receptor 2 (FGFR2)
  • Fibroblast growth factor receptor 4 (FGFR4)
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • Histone-arginine methyltransferase CARM1
  • Histone-lysine N-methyltransferase SETDB1
  • Histone-lysine N-methyltransferase SMYD3
  • Histone-lysine N-methyltransferase SUV39H2 (Suv39H2)
  • Histone-lysine N-methyltransferase, H3 lysine-79 specific
  • Interleukin-1 receptor-associated kinase 1 (IRAK1)
  • Interleukin-1 receptor-associated kinase 4
  • Kinase insert domain receptor (KDR)
  • MLL
  • Mitogen-activated protein kinase kinase kinase 8 (MAP3K8)
  • Mitogen-activated protein kinase kinase kinase kinase 4
  • Muscarinic acetylcholine receptor M2
  • N-lysine methyltransferase SETD6 (SETD6)
  • Nuclear SET domain-containing protein 1 (NSD1)
  • Nuclear SET domain-containing protein 2 (NSD2)
  • Nuclear SET domain-containing protein 3 (NSD3)
  • Nuclear receptor subfamily 1 group I member 2
  • PRMT5/MEP50 Enzyme
  • Platelet-derived growth factor receptor alpha (PDGFRa)
  • Polycomb protein EED (EED)
  • Polycomb repressive complex 2 (PRC2)
  • Potassium voltage-gated channel subfamily H member 2
  • Protein G9a (G9a)
  • Protein arginine methyltransferase 3 (PRMT3)
  • Protein arginine methyltransferase 8 (PRMT8)
  • Protein kinase C alpha type
  • Protein kinase C theta type
  • Protein-arginine N-methyltransferase 1
  • Receptor-type tyrosine-protein kinase FLT3 (FLT3)
  • Rho-associated protein kinase 2 (ROCK2)
  • SET and MYND domain-containing protein 2 (SMYD2)
  • SET domain-containing protein 2 (SETD2)
  • SET domain-containing protein 7/9 (Set7/9)
  • SET domain-containing protein 8 (SetD8)
  • Serine/threonine-protein kinase 17B (STK17B)
  • Serine/threonine-protein kinase 4 (STK4)
  • Sodium-dependent dopamine transporter
  • Sodium-dependent noradrenaline transporter
  • Sodium-dependent serotonin transporter
  • Tyrosine-protein kinase ABL1
  • Tyrosine-protein kinase BTK
  • Tyrosine-protein kinase JAK2
  • Tyrosine-protein kinase Lyn
  • Tyrosine-protein kinase SYK
  • Tyrosine-protein kinase ZAP-70
  • alpha-1 Nicotinic AChR
74 IC50 3 Kd
  • EED226
  • 5-HT3A Serotonin Receptor
  • 5-hydroxytryptamine receptor 1A
  • 5-hydroxytryptamine receptor 1B
  • 5-hydroxytryptamine receptor 1D
  • 5-hydroxytryptamine receptor 2A
  • 5-hydroxytryptamine receptor 2C
  • 5-hydroxytryptamine receptor 6
  • 5-hydroxytryptamine receptor 7
  • 5-hydroxytryptamine receptor 7 (5HT7)
  • ADRA1B
  • Adrenergic receptor alpha-1
  • Adrenergic receptor alpha-2
  • Alpha-1 Adrenergic Receptor/ adrenergic receptor/ adrenergic receptor
  • Alpha-1A adrenergic receptor
  • Alpha-1D adrenergic receptor
  • Alpha-2A adrenergic receptor
  • Alpha-2B adrenergic receptor
  • Alpha-2C adrenergic receptor
  • Beta-1 adrenergic receptor
  • Beta-2 adrenergic receptor
  • Bile salt export pump
  • CCKBR
  • Calcium channel
  • Canalicular multispecific organic anion transporter 1
  • Canalicular multispecific organic anion transporter 2
  • Cerebral cortex alpha adrenergic receptor
  • Cholecystokinin B
  • Cholinergic, muscarinic
  • Cysteinyl leukotriene receptor 1
  • D(1A) dopamine receptor
  • D(2) dopamine receptor
  • D(3) dopamine receptor
  • D(4) dopamine receptor
  • Delta-type opioid receptor
  • Dopamine receptor
  • Gamma-aminobutyric acid receptor subunit alpha-1
  • HTR2C
  • HTR6
  • Histamine H1 receptor
  • Kappa-type opioid receptor
  • Mu-type opioid receptor
  • Multidrug resistance-associated protein 4
  • Muscarinic acetylcholine receptor
  • Muscarinic acetylcholine receptor M2
  • Muscarinic acetylcholine receptor M3
  • NT
  • Norepinephrine transporter
  • P-glycoprotein 1
  • Potassium voltage-gated channel subfamily H member 2
  • Prostanoid TP receptor
  • Serotonin (5-HT) receptor
  • Serotonin 1B/1D receptor
  • Serotonin 2 (5-HT2) receptor
  • Serotonin receptor 2a and 2c (5HT2A and 5HT2C)
  • Sigma non-opioid intracellular receptor 1
  • Sodium channel protein type 7 subunit alpha
  • Sodium-dependent dopamine transporter
  • Sodium-dependent serotonin transporter
  • Substance P
  • Voltage-gated L-type calcium channel
  • Voltage-gated potassium channel subunit Kv1.5
  • Voltage-gated sodium channel subunit alpha Nav1.8
  • adrenergic Alpha2
140 Ki 34 IC50
  • 1-(2-{4-[5-chloro-1-(4-fluorophenyl)-1H-indol-3-yl]piperidin-1-yl}ethyl)imidazolidin-2-one
  • 1-[2-[4-[5-chloro-1-(4-fluorophenyl)-indol-3-yl]-1-piperidyl]ethyl]imidazolidin-2-one
  • CHEMBL12713
  • Sertindole