Compile Data Set for Download or QSAR
Report error Found 134 Enz. Inhib. hit(s) with Target = 'cAMP-specific 3',5'-cyclic phosphodiesterase 4C [2-712]'
LigandChemical structure of BindingDB Monomer ID 577094BDBM577094(US11472805, Example 11 | (7S)-10-(4-Chlorophenyl)-...)
Affinity DataIC50: 0.570nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577126BDBM577126(US11472805, Example 32 | 10-(4-Chloro-3-fluorophen...)
Affinity DataIC50: 1.44nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577172BDBM577172(US11472805, Example 76 | 10-(4-Chloro-3-fluorophen...)
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577123BDBM577123(US11472805, Example 29 | 10-(4-Chloro-5-fluoro-2-m...)
Affinity DataIC50: 2.45nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577128BDBM577128(US11472805, Example 34 | 2-Chloro-5-(8-cyclopropyl...)
Affinity DataIC50: 2.88nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577142BDBM577142(US11472805, Example 47 | 10-(4-Chloro-2-fluorophen...)
Affinity DataIC50: 2.88nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577143BDBM577143(US11472805, Example 48 | 10-(3-Chlorophenyl)-8-cyc...)
Affinity DataIC50: 3.16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577131BDBM577131(US11472805, Example 37 | 8-Cyclopropyl-10-(4-fluor...)
Affinity DataIC50: 3.30nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577130BDBM577130(US11472805, Example 36 | 10-(3-Chloro-4-fluorophen...)
Affinity DataIC50: 3.48nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577077BDBM577077(US11472805, Example 2 | 10-(4-Chlorophenyl)-8-cycl...)
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577135BDBM577135(US11472805, Example 40 | 8-Cyclopropyl-10-(3,4,5-t...)
Affinity DataIC50: 4.36nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577129BDBM577129(US11472805, Example 35 | 8-Cyclopropyl-10-(2,3-dih...)
Affinity DataIC50: 5.52nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577173BDBM577173(US11472805, Example 77 | 10-(4-Chloro-2,5-difluoro...)
Affinity DataIC50: 5.94nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577096BDBM577096(US11472805, Example 13 | 8-Cyclopropyl-10-(4-methy...)
Affinity DataIC50: 6.59nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577141BDBM577141(US11472805, Example 46 | 8-Cyclopropyl-10-(2,5-dif...)
Affinity DataIC50: 6.98nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577140BDBM577140(US11472805, Example 45 | 8-Cyclopropyl-10-(3-fluor...)
Affinity DataIC50: 7.88nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577166BDBM577166(US11472805, Example 70 | 4-(8-Cyclopropyl-9-oxo-8,...)
Affinity DataIC50: 8.55nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577121BDBM577121(US11472805, Example 27 | 9-(4-Chlorophenyl)-7-cycl...)
Affinity DataIC50: 9.03nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577136BDBM577136(US11472805, Example 41 | 8-Cyclopropyl-10-(3-fluor...)
Affinity DataIC50: 9.22nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577144BDBM577144(US11472805, Example 49 | 8-Cyclopropyl-10-(4-fluor...)
Affinity DataIC50: 9.39nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577145BDBM577145(US11472805, Example 50 | 4-(8-Cyclopropyl-9-oxo-6,...)
Affinity DataIC50: 9.62nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577152BDBM577152(US11472805, Example 57 | 10-(4-Chlorophenyl)-8-(5-...)
Affinity DataIC50: 10.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577127BDBM577127(US11472805, Example 33 | 8-Cyclopropyl-10-(3,4-dim...)
Affinity DataIC50: 11.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577107BDBM577107(US11472805, Example 20 | 8-Cyclopropyl-10-(4-methy...)
Affinity DataIC50: 11.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577171BDBM577171(US11472805, Example 75 | 10-(4-Chlorophenyl)-8-cyc...)
Affinity DataIC50: 11.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577161BDBM577161(US11472805, Example 65 | 8-Cyclopropyl-10-(2,4-dim...)
Affinity DataIC50: 13.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577091BDBM577091(US11472805, Example 8 | 10-(4-Chloro-3-fluoropheny...)
Affinity DataIC50: 13.9nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577120BDBM577120(US11472805, Example 26 | 5-(8-Cyclopropyl-9-oxo-6,...)
Affinity DataIC50: 14.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577168BDBM577168(US11472805, Example 72 | 4-(7-Cyclopropyl-8-oxo-5,...)
Affinity DataIC50: 15.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577101BDBM577101(US11472805, Example 16 | 4-(8-Cyclopropyl-9-oxo-3,...)
Affinity DataIC50: 15.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 457828BDBM457828(US10738063, Example 58)
Affinity DataIC50: 16.4nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577162BDBM577162(US11472805, Example 66 | 8-Cyclopropyl-10-(2,4-dim...)
Affinity DataIC50: 16.7nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577079BDBM577079(US11472805, Example 4 | 4-(8-Cyclopropyl-9-oxo-6,7...)
Affinity DataIC50: 17nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577182BDBM577182(US11472805, Example 86 | 10-Cyclopentyl-8-cyclopro...)
Affinity DataIC50: 18.1nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577109BDBM577109(US11472805, Example 22 | 4-(8-Cyclopropyl-9-oxo-6,...)
Affinity DataIC50: 20.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577122BDBM577122(US11472805, Example 28 | 4-(7-Cyclopropyl-8-oxo-5,...)
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577133BDBM577133(US11472805, Example 38 | 8-Cyclopropyl-10-(2,4-dif...)
Affinity DataIC50: 21nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577095BDBM577095(US11472805, Example 12 | 10-(4-Chlorophenyl)-2-cyc...)
Affinity DataIC50: 23.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577163BDBM577163(US11472805, Example 67 | US11472805, Example 69 | ...)
Affinity DataIC50: 24.3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577103BDBM577103(US11472805, Example 18 | 10-(4-Chlorophenyl)-8-cyc...)
Affinity DataIC50: 24.4nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577115BDBM577115(US11472805, Example 24 | 8-Cyclopropyl-10-(3,5-dif...)
Affinity DataIC50: 24.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577163BDBM577163(US11472805, Example 67 | US11472805, Example 69 | ...)
Affinity DataIC50: 26nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577093BDBM577093(US11472805, Example 10 | (7R)-10-(4-Chlorophenyl)-...)
Affinity DataIC50: 28.2nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 399978BDBM399978(US10323042, Example 57 | US10738063, Example 57)
Affinity DataIC50: 28.5nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 399927BDBM399927(US10323042, Example 7 | (6S)-3-(4-Chloro-2,5-diflu...)
Affinity DataIC50: 31.4nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577149BDBM577149(US11472805, Example 54 | 8-Cyclopropyl-10-(2-fluor...)
Affinity DataIC50: 35.8nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577160BDBM577160(US11472805, Example 64 | 8-Cyclopropyl-10-(furo[3,...)
Affinity DataIC50: 37.5nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 399967BDBM399967(US10323042, Example 47 | US10738063, Example 47)
Affinity DataIC50: 45.8nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 399952BDBM399952(US10323042, Example 32 | US10738063, Example 32)
Affinity DataIC50: 48.2nMAssay Description:Human PDE4C1 coding sequence (amino acids 2 to 712 from the sequence with accession number NP_000914.2) was cloned into the baculovirus expression ve...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/4/2021
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 577170BDBM577170(US11472805, Example 74 | 10-(4-Chloro-3-fluorophen...)
Affinity DataIC50: 52nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/24/2022
Entry Details
US Patent

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