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Found 63 with Last Name = 'wills' and Initial = 'n'
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090249(3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfon...)
Affinity DataKi:  6nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090249(3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfon...)
Affinity DataKi:  6nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090222(CHEMBL39086 | MD805 Analogue)
Affinity DataKi:  26nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50077058(3,3-Dimethyl-1,2,3,4-tetrahydro-quinoline-8-sulfon...)
Affinity DataKi:  26nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090244(3,3-Dimethyl-6-[3-oxo-3-(4-pyridin-4-ylmethyl-pipe...)
Affinity DataKi:  27nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090222(CHEMBL39086 | MD805 Analogue)
Affinity DataKi:  28nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090250(3-(8-{(S)-1-Benzothiazol-2-ylmethyl-2-[4-(2-fluoro...)
Affinity DataKi:  34nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090247(6-[3-(4-Acetyl-piperazin-1-yl)-3-oxo-propyl]-3,3-d...)
Affinity DataKi:  34nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090243(6-(2-Hydroxy-ethyl)-3,3-dimethyl-1,2,3,4-tetrahydr...)
Affinity DataKi:  39nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090246(3,3-Dimethyl-6-(2-ureido-ethyl)-1,2,3,4-tetrahydro...)
Affinity DataKi:  47nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090238(3,3-Dimethyl-6-{3-[4-(2-morpholin-4-yl-2-oxo-ethyl...)
Affinity DataKi:  57nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090245(6-Hydroxymethyl-3,3-dimethyl-1,2,3,4-tetrahydro-qu...)
Affinity DataKi:  64nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090248(CHEMBL43397 | Methyl-carbamic acid 8-{(S)-1-benzot...)
Affinity DataKi:  77nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090241(3-(8-{(S)-1-Benzothiazol-2-ylmethyl-2-[4-(2-fluoro...)
Affinity DataKi:  82nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090242(4-(8-{(S)-1-Benzothiazol-2-ylmethyl-2-[4-(2-fluoro...)
Affinity DataKi:  94nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090226(3-Methyl-1,2,3,4-tetrahydro-quinoline-8-sulfonic a...)
Affinity DataKi:  118nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090226(3-Methyl-1,2,3,4-tetrahydro-quinoline-8-sulfonic a...)
Affinity DataKi:  118nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090253(6-(3-Hydroxy-propyl)-3,3-dimethyl-1,2,3,4-tetrahyd...)
Affinity DataKi:  119nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090251(6-(2-Methoxy-ethoxymethoxymethyl)-3,3-dimethyl-1,2...)
Affinity DataKi:  125nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50366643(CHEMBL1907778)
Affinity DataKi:  126nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090231(CHEMBL39375 | MD805 Analogue)
Affinity DataKi:  248nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50366642(CHEMBL1907779)
Affinity DataKi:  280nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090240(8-{(S)-1-Benzothiazol-2-ylmethyl-2-[4-(2-fluoro-et...)
Affinity DataKi:  359nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090236(CHEMBL418248 | MD805 Analogue)
Affinity DataKi:  452nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090239((8-{(S)-1-Benzothiazol-2-ylmethyl-2-[4-(2-fluoro-e...)
Affinity DataKi:  500nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090252(8-{(S)-1-Benzothiazol-2-ylmethyl-2-[4-(2-fluoro-et...)
Affinity DataKi:  723nMAssay Description:Evaluated for the binding affinity against thrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090235(CHEMBL38907 | MD805 Analogue)
Affinity DataKi:  760nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090237(CHEMBL43074 | MD805 Analogue)
Affinity DataKi:  780nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090220(CHEMBL289623 | MD805 Analogue)
Affinity DataKi:  810nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50366643(CHEMBL1907778)
Affinity DataKi:  1.32E+3nMAssay Description:Compound was evaluated for its inhibitory activity against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090234(CHEMBL40904 | MD805 Analogue)
Affinity DataKi:  1.57E+3nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSerine protease 1(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50366642(CHEMBL1907779)
Affinity DataKi:  1.78E+3nMAssay Description:Compound was evaluated for its inhibitory activity against TrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090230(CHEMBL38617 | MD805 Analogue)
Affinity DataKi:  2.19E+3nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090224(CHEMBL289493 | MD805 Analogue)
Affinity DataKi:  3.10E+3nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090227(CHEMBL288938 | MD805 Analogue)
Affinity DataKi:  3.28E+3nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50366643(CHEMBL1907778)
Affinity DataKi:  4.00E+3nMAssay Description:Compound was evaluated for its inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090228(CHEMBL289628 | MD805 Analogue)
Affinity DataKi:  4.56E+3nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090231(CHEMBL39375 | MD805 Analogue)
Affinity DataKi:  4.91E+3nMAssay Description:Compound was evaluated for its inhibitory activity against Serine protease chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50366642(CHEMBL1907779)
Affinity DataKi:  6.20E+3nMAssay Description:Compound was evaluated for its inhibitory activity against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090225(3-Methyl-1,2,3,4-tetrahydro-quinoline-8-sulfonic a...)
Affinity DataKi:  6.70E+3nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090226(3-Methyl-1,2,3,4-tetrahydro-quinoline-8-sulfonic a...)
Affinity DataKi:  7.55E+3nMAssay Description:Compound was evaluated for its inhibitory activity against Serine protease chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090222(CHEMBL39086 | MD805 Analogue)
Affinity DataKi:  8.40E+3nMAssay Description:Compound was evaluated for its inhibitory activity against Serine protease chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50366643(CHEMBL1907778)
Affinity DataKi:  1.20E+4nMAssay Description:Compound was evaluated for its inhibitory activity against Serine protease chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090238(3,3-Dimethyl-6-{3-[4-(2-morpholin-4-yl-2-oxo-ethyl...)
Affinity DataKi:  1.22E+4nMAssay Description:Inhibitory activity against Serine protease chymotrypsinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50366644(CHEMBL1907777)
Affinity DataKi:  1.96E+4nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090226(3-Methyl-1,2,3,4-tetrahydro-quinoline-8-sulfonic a...)
Affinity DataKi:  4.50E+4nMAssay Description:Compound was evaluated for its inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-1(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090226(3-Methyl-1,2,3,4-tetrahydro-quinoline-8-sulfonic a...)
Affinity DataKi:  4.50E+4nMAssay Description:Compound was evaluated for its inhibitory activity against kallikreinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090223(3-Methyl-1,2,3,4-tetrahydro-quinoline-8-sulfonic a...)
Affinity DataKi:  4.73E+4nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProthrombin(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50090232(CHEMBL40319 | MD805 Analogue)
Affinity DataKi:  5.99E+4nMAssay Description:Compound was evaluated for its inhibitory activity against ThrombinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCoagulation factor X(Homo sapiens (Human))
Novartis Horsham Research Centre

Curated by ChEMBL
LigandPNGBDBM50366642(CHEMBL1907779)
Affinity DataKi:  8.70E+4nMAssay Description:Compound was evaluated for its inhibitory activity against Coagulation factor XMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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