Compile Data Set for Download or QSAR
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Found 72 Enz. Inhib. hit(s) with all data for entry = 10642
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448940(N-(5-(4-Ethylpiperazin-1-yl)pyridin-2-yl)-5-fluoro...)
Affinity DataIC50:  0.0700nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448950(N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...)
Affinity DataIC50:  0.0800nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556330(N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...)
Affinity DataIC50:  0.100nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556335(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  0.110nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556334(3-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...)
Affinity DataIC50:  0.110nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448926(1-(2-((5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihyd...)
Affinity DataIC50:  0.120nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM50455050(CHEMBL4208172 | US10696678, Example 18 | US1135117...)
Affinity DataIC50:  0.140nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556329(N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...)
Affinity DataIC50:  0.160nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448950(N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...)
Affinity DataIC50:  0.170nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556328((S)—N-(5-(3-(dimethylamino)pyrrolidin-1-yl)py...)
Affinity DataIC50:  0.180nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556327((S)-(3-(dimethylamino)pyrrolidin-1-yl)(6-(5-fluoro...)
Affinity DataIC50:  0.200nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556336(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  0.25nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556337(2-(4-(6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dih...)
Affinity DataIC50:  0.25nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556331(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  0.260nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)
Affinity DataIC50:  0.260nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)
Affinity DataIC50:  0.260nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556326(1-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...)
Affinity DataIC50:  0.730nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448940(N-(5-(4-Ethylpiperazin-1-yl)pyridin-2-yl)-5-fluoro...)
Affinity DataIC50:  0.880nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556334(3-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...)
Affinity DataIC50:  1.02nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556327((S)-(3-(dimethylamino)pyrrolidin-1-yl)(6-(5-fluoro...)
Affinity DataIC50:  1.19nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448926(1-(2-((5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihyd...)
Affinity DataIC50:  1.87nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556335(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  1.89nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448950(N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...)
Affinity DataIC50:  1.93nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448950(N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...)
Affinity DataIC50:  2.42nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556331(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  2.46nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM50455050(CHEMBL4208172 | US10696678, Example 18 | US1135117...)
Affinity DataIC50:  2.71nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556337(2-(4-(6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dih...)
Affinity DataIC50:  2.72nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556330(N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...)
Affinity DataIC50:  2.90nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)
Affinity DataIC50:  3.41nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM50110183(Abemaciclib | LY-2835219 | US10626107, Example LY2...)
Affinity DataIC50:  3.41nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556336(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  3.92nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556328((S)—N-(5-(3-(dimethylamino)pyrrolidin-1-yl)py...)
Affinity DataIC50:  3.96nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556329(N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...)
Affinity DataIC50:  4.72nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 6(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556326(1-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...)
Affinity DataIC50:  8.84nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were respectively dissolved in ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 4(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556338(N-(5-((4-ethylpiperazin-1-yl)methyl)pyridin-2-yl)-...)
Affinity DataIC50:  9.46nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556330(N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...)
Affinity DataIC50:  11.3nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448926(1-(2-((5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihyd...)
Affinity DataIC50:  17.6nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556327((S)-(3-(dimethylamino)pyrrolidin-1-yl)(6-(5-fluoro...)
Affinity DataIC50:  19.1nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556327((S)-(3-(dimethylamino)pyrrolidin-1-yl)(6-(5-fluoro...)
Affinity DataIC50:  20.4nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556330(N-(5-((1-ethylpiperidin-4-yl)methoxy)pyridin-2-yl)...)
Affinity DataIC50:  24.7nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448926(1-(2-((5-Fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihyd...)
Affinity DataIC50:  36.8nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448950(N-(5-(1-Ethylpiperidine-4-yl)pyridin-2-yl)-5-fluor...)
Affinity DataIC50:  38.3nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556334(3-(4-((6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-di...)
Affinity DataIC50:  44.9nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM448940(N-(5-(4-Ethylpiperazin-1-yl)pyridin-2-yl)-5-fluoro...)
Affinity DataIC50:  46.8nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556328((S)—N-(5-(3-(dimethylamino)pyrrolidin-1-yl)py...)
Affinity DataIC50:  50.6nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM50455050(CHEMBL4208172 | US10696678, Example 18 | US1135117...)
Affinity DataIC50:  51.1nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556335(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  55.2nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556331(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dihydro-1H-b...)
Affinity DataIC50:  64.1nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556328((S)—N-(5-(3-(dimethylamino)pyrrolidin-1-yl)py...)
Affinity DataIC50:  65.5nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
Beijing Xuanyi Pharmasciences

US Patent
LigandPNGBDBM556337(2-(4-(6-(5-fluoro-4-(5-fluoro-1,1-dimethyl-2,3-dih...)
Affinity DataIC50:  70.3nMAssay Description:Test compounds (compound of the present invention, reference compound Abemaciclib, and comparative example compounds) were dissolved in DMSO at 10 mM...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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